Thursday, November 20, 2014

Nature Reviews Neuroscience contents December 2014 Volume 15 Number 12 pp 765-834

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Nature Reviews Neuroscience

 
TABLE OF CONTENTS
 
December 2014 Volume 15 Number 12
Nature Reviews Neuroscience cover
Impact Factor 31.376 *
In this issue
Research Highlights
Reviews
Perspectives

Also this month
Article series:
The endocannabinoid system

 Featured article:
Neuroscience and education: myths and messages
Paul A. Howard-Jones


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RESEARCH HIGHLIGHTS
Top

Neurodegenerative disease: New dimensions in Alzheimer's modelling
p765 | doi:10.1038/nrn3860
A three-dimensional human cell culture model of Alzheimer's disease recapitulates both amyloid-β and tau pathology.

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GLIA: Oligodendrocytes rev up motor learning
p766 | doi:10.1038/nrn3864
New oligodendrocytes that are derived from oligodendrocyte-precursor cells and express myelin regulatory factor are important for the learning of novel motor skills.

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Dendrites: Regenerating space
p766 | doi:10.1038/nrn3870
Place-cell firing in mice can be accompanied by regenerative dendritic events, which predict some of the properties of place fields.

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Learning and memory: A memorable double act
p767 | doi:10.1038/nrn3859
During memory retrieval the hippocampus is required for the reactivation of cortical activity patterns that occurred during encoding, but artificial reactivation of the cortical representation of a memory alone is sufficient to drive recall.

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Behavioural neuroscience: Socially interactive interneurons
p768 | doi:10.1038/nrn3861
A subpopulation of cortical neurons that express oxytocin receptors mediates female sociosexual behaviour in mice.

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Psychiatric disorders: A feat of epigenetic engineering
p768 | doi:10.1038/nrn3869
Study uses in vivo gene-specific chromatin remodelling to elucidate the role of Fosb in addiction- and depression-related changes in the brain.

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IN BRIEF

Synaptic physiology: No clathrin required | Neurodegenerative disorders: Tangled up | Synaptic plasticity: Opening a closed window | Neurobiology of reward: Great expectations | Psychiatric disorders: GluN2B mediates ketamine's antidepressant effect | Glia: Glial ankyrins function at the junction | Neurogenesis: Fat cells send messages to the brain
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REVIEWS
Top
Polyunsaturated fatty acids and their metabolites in brain function and disease
Richard P. Bazinet & Sophie Layé
p771 | doi:10.1038/nrn3820
Polyunsaturated fatty acids (PUFAs) and their biologically active derivatives regulate many processes in the brain, including neurotransmission, cell survival and inflammation. Bazinet and Layé review PUFA metabolism and functions in the brain and discuss the potential for PUFA supplementation in psychiatric and neurodegenerative disorders.
Abstract | Full Text | PDF

Article series: The endocannabinoid system
Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies
Mauro Maccarrone, Manuel Guzmán, Ken Mackie, Patrick Doherty & Tibor Harkany
p786 | doi:10.1038/nrn3846
Endocannabinoids are involved in regulating neural progenitor cell proliferation, as well as neuronal and glial differentiation. In this Review, Maccarrone, Harkany and colleagues discuss mechanisms of endocannabinoid signalling, the action of plant cannabinoids in the foetal brain, and their exploitation to modulate diseases associated with defective cell cycle control, particularly cancer.
Abstract | Full Text | PDF

The molecular bases of the suicidal brain
Gustavo Turecki
p802 | doi:10.1038/nrn3839
Suicide is one of the leading causes of death for people of all ages in the developed world and is associated with various risk factors. Here, Gustavo Turecki reviews the molecular processes that may predispose individuals to suicide, mediate suicidal ideation and behaviour, and trigger suicidal events.
Abstract | Full Text | PDF | Supplementary information

Corrigendum: The role of orexin in motivated behaviours
Takeshi Sakurai
p816 | doi:10.1038/nrn3862
Full Text | PDF
Erratum: Expectation in perceptual decision making: neural and computational mechanisms
Christopher Summerfield & Floris P. de Lange
p816 | doi:10.1038/nrn3863
Full Text | PDF
 
PERSPECTIVES
Top
SCIENCE AND SOCIETY
Neuroscience and education: myths and messages
Paul A. Howard-Jones
p817 | doi:10.1038/nrn3817
Myths about the brain — neuromyths — have established themselves among teachers worldwide, often contributing to poor practice. Paul Howard-Jones shows how fact became distorted into popular neuromyth by biases and cultural conditions that largely remain, threatening current attempts at authentic dialogue between neuroscience and education.
Abstract | Full Text | PDF

SCIENCE AND SOCIETY
The warrior in the machine: neuroscience goes to war
Irene Tracey & Rod Flower
p825 | doi:10.1038/nrn3835
In this Science and Society article, Tracey and Flower examine how insights and techniques from neuroscience have been and might be used by the military. They also highlight some of the ethical issues raised by the use of neuroscientific knowledge in this context.
Abstract | Full Text | PDF

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