Molecular Therapy - Table of Contents alert Volume 21 Issue 4

TABLE OF CONTENTS Volume 21, Issue 4 (April 2013) In this issue Editorial In This Issue Research Highlights Commentaries Reviews Original Articles Corrigendum Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement FREE 91 page eBook: Key Advances in Medicine An essential resource for anyone with an interest in medicine, 45 articles summarise the groundbreaking clinical studies of 2012 and highlight trends to watch out for in 2013. Download FREE PDF now!   Editorial Top Moving Forward on Shifting Sands: Ethical Regulation of Gene Therapy Clinical Trials in the United Kingdom Emma Morris, Martin Gore, Andrew Baker and Adrian J Thrasher Mol Ther 2013 21: 715-716; 10.1038/mt.2013.43 Full Text In This Issue Top In This Issue Mol Ther 2013 21: 718; 10.1038/mt.2013.44 Full Text Research Highlights Top Research Highlights Mol Ther 2013 21: 719; 10.1038/mt.2013.45 Full Text Commentaries Top A Crisper Look at Genome Editing: RNA-guided Genome Modification Mara Damian and Matthew H Porteus Mol Ther 2013 21: 720-722; 10.1038/mt.2013.46 Full Text “Infectious” Optimism for Treatment of Hepatocellular Carcinoma Kenneth K Tanabe and E Antonio Chiocca Mol Ther 2013 21: 722-724; 10.1038/mt.2013.47 Full Text Reviews Top Mechanistic, Technical, and Clinical Perspectives in Therapeutic Stimulation of Coronary Collateral Development by Angiogenic Growth Factors Gabor M Rubanyi Mol Ther 2013 21: 725-738; advance online publication, February 12, 2013; 10.1038/mt.2013.13 Abstract | Full Text Baculovirus: an Insect-derived Vector for Diverse Gene Transfer Applications Kari J Airenne, Yu-Chen Hu, Thomas A Kost, Richard H Smith, Robert M Kotin, Chikako Ono, Yoshiharu Matsuura, Shu Wang and Seppo Ylä-Herttuala Mol Ther 2013 21: 739-749; advance online publication, February 26, 2013; 10.1038/mt.2012.286 Abstract | Full Text Original Articles Top Microdystrophin Ameliorates Muscular Dystrophy in the Canine Model of Duchenne Muscular Dystrophy Jin-Hong Shin, Xiufang Pan, Chady H Hakim, Hsiao T Yang, Yongping Yue, Keqing Zhang, Ronald L Terjung and Dongsheng Duan Mol Ther 2013 21: 750-757; advance online publication, January 15, 2013; 10.1038/mt.2012.283 Abstract | Full Text Insulin-like Growth Factor-binding Protein-7 (IGFBP7): A Promising Gene Therapeutic for Hepatocellular Carcinoma (HCC) Dong Chen, Ayesha Siddiq, Luni Emdad, Devaraja Rajasekaran, Rachel Gredler, Xue-Ning Shen, Prasanna K Santhekadur, Jyoti Srivastava, Chadia L Robertson, Igor Dmitriev, Elena A Kashentseva, David T Curiel, Paul B Fisher and Devanand Sarkar Mol Ther 2013 21: 758-766; advance online publication, January 15, 2013; 10.1038/mt.2012.282 Abstract | Full Text SR-A and SREC-I Are Kupffer and Endothelial Cell Receptors for Helper-dependent Adenoviral Vectors Pasquale Piccolo, Francesco Vetrini, Pratibha Mithbaokar, Nathan C Grove, Terry Bertin, Donna Palmer, Philip Ng and Nicola Brunetti-Pierri Mol Ther 2013 21: 767-774; advance online publication, January 29, 2013; 10.1038/mt.2012.287 Abstract | Full Text Proteomic and Functional Analyses of Protein–DNA Complexes During Gene Transfer Melissa A Badding, John D Lapek, Alan E Friedman and David A Dean Mol Ther 2013 21: 775-785; advance online publication, November 20, 2012; 10.1038/mt.2012.231 Abstract | Full Text Generation of an HIV Resistant T-cell Line by Targeted “Stacking” of Restriction Factors Richard A Voit, Moira A McMahon, Sara L Sawyer and Matthew H Porteus Mol Ther 2013 21: 786-795; advance online publication, January 29, 2013; 10.1038/mt.2012.284 Abstract | Full Text Differential Type I Interferon-dependent Transgene Silencing of Helper-dependent Adenoviral vs. Adeno-associated Viral Vectors In Vivo Masataka Suzuki, Terry K Bertin, Geoffrey L Rogers, Racel G Cela, Irene Zolotukhin, Donna J Palmer, Philip Ng, Roland W Herzog and Brendan Lee Mol Ther 2013 21: 796-805; advance online publication, January 15, 2013; 10.1038/mt.2012.277 Abstract | Full Text Gene Therapy Researchers' Assessments Of Risks And Perceptions Of Risk Acceptability In Clinical Trials Claire T. Deakin, Ian E. Alexander, Cliff A. Hooker and Ian H. Kerridge Mol Ther 2013 21: 806-815; advance online publication, January 22, 2013; 10.1038/mt.2012.230 Abstract | Full Text Enhanced Intrapulmonary Delivery of Anticancer siRNA for Lung Cancer Therapy Using Cationic Ethylphosphocholine-based Nanolipoplexes Gayong Shim, Hyun-woo Choi, Sangbin Lee, Junhyeok Choi, Yong Hee Yu, Da-Eui Park, Yongseok Choi, Chan-Wha Kim and Yu-Kyoung Oh Mol Ther 2013 21: 816-824; advance online publication, February 5, 2013; 10.1038/mt.2013.10 Abstract | Full Text Lentiviral Delivery of RNAi for In Vivo Lineage-Specific Modulation of Gene Expression in Mouse Lung Macrophages Andrew A Wilson, Letty W Kwok, Emily L Porter, Julie G Payne, Gregory S McElroy, Sarah J Ohle, Sara R Greenhill, Matthew T Blahna, Kazuko Yamamoto, Jyh C Jean, Joseph P Mizgerd and Darrell N Kotton Mol Ther 2013 21: 825-833; advance online publication, February 12, 2013; 10.1038/mt.2013.19 Abstract | Full Text siRNA Targeting Hes5 Augments Hair Cell Regeneration in Aminoglycoside-damaged Mouse Utricle Jae Yun Jung, Matt R. Avenarius, Swetlana Adamsky, Evgenia Alpert, Elena Feinstein and Yehoash Raphael Mol Ther 2013 21: 834-841; advance online publication, February 26, 2013; 10.1038/mt.2013.18 Abstract | Full Text Targeting and Killing of Metastatic Cells in the Transgenic Adenocarcinoma of Mouse Prostate Model With Vesicular Stomatitis Virus Maryam Moussavi, Howard Tearle, Ladan Fazli, John C Bell, William Jia and Paul S Rennie Mol Ther 2013 21: 842-848; advance online publication, January 22, 2013; 10.1038/mt.2012.285 Abstract | Full Text DARPin-targeting of Measles Virus: Unique Bispecificity, Effective Oncolysis, and Enhanced Safety Katrin Friedrich, Jan RH Hanauer, Steffen Prüfer, Robert C Münch, Iris Völker, Christodoulos Filippis, Christian Jost, Kay-Martin Hanschmann, Roberto Cattaneo, Kah-Whye Peng, Andreas Plückthun, Christian J Buchholz, Klaus Cichutek and Michael D Mühlebach Mol Ther 2013 21: 849-859; advance online publication, February 5, 2013; 10.1038/mt.2013.16 Abstract | Full Text The Use of Scaffold-free Cell Sheet Technique to Refine Mesenchymal Stromal Cell-based Therapy for Heart Failure Takuya Narita, Yasunori Shintani, Chiho Ikebe, Masahiro Kaneko, Niall G Campbell, Steven R Coppen, Rakesh Uppal, Yoshiki Sawa, Kenta Yashiro and Ken Suzuki Mol Ther 2013 21: 860-867; advance online publication, January 29, 2013; 10.1038/mt.2013.9 Abstract | Full Text Busulfan Conditioning Enhances Engraftment of Hematopoietic Donor-derived Cells in the Brain Compared With Irradiation Fiona L Wilkinson, Ana Sergijenko, Kia J Langford-Smith, Marcela Malinowska, Rob F Wynn and Brian W Bigger Mol Ther 2013 21: 868-876; advance online publication, February 19, 2013; 10.1038/mt.2013.29 Abstract | Full Text Generation and Preclinical Characterization of a Fc-optimized GITR-Ig Fusion Protein for Induction of NK Cell Reactivity Against Leukemia Benjamin Joachim Schmiedel, Antje Werner, Julia Steinbacher, Tina Nuebling, Corina Buechele, Ludger Grosse-Hovest and Helmut Rainer Salih Mol Ther 2013 21: 877-886; advance online publication, February 5, 2013; 10.1038/mt.2013.11 Abstract | Full Text HDAC Inhibition Suppresses Primary Immune Responses, Enhances Secondary Immune Responses, and Abrogates Autoimmunity During Tumor Immunotherapy Byram W Bridle, Lan Chen, Chantal G Lemay, Jean-Simon Diallo, Jonathan Pol, Andrew Nguyen, Alfredo Capretta, Rongqiao He, Jonathan L Bramson, John C Bell, Brian D Lichty and Yonghong Wan Mol Ther 2013 21: 887-894; advance online publication, January 8, 2013; 10.1038/mt.2012.265 Abstract | Full Text Rescue of Impaired NK Cell Activity in Hodgkin Lymphoma With Bispecific Antibodies In Vitro and in PatientsMTOpen Katrin S. Reiners, Jörg Kessler, Maike Sauer, Achim Rothe, Hinrich P. Hansen, Uwe Reusch, Christian Hucke, Ulrike Köhl, Horst Dürkop, Andreas Engert and Elke Pogge von Strandmann Mol Ther 2013 21: 895-903; advance online publication, March 5, 2013; 10.1038/mt.2013.14 Abstract | Full Text Treatment of Metastatic Renal Cell Carcinoma With CAIX CAR-engineered T cells: Clinical Evaluation and Management of On-target Toxicity Cor HJ Lamers, Stefan Sleijfer, Sabine van Steenbergen, Pascal van Elzakker, Brigitte van Krimpen, Corrien Groot, Arnold Vulto, Michael den Bakker, Egbert Oosterwijk, Reno Debets and Jan W Gratama Mol Ther 2013 21: 904-912; advance online publication, February 19, 2013; 10.1038/mt.2013.17 Abstract | Full Text Corrigendum Top The Efficacy Versus Toxicity Profile of Combination Virotherapy and TLR Immunotherapy Highlights the Danger of Administering TLR Agonists to Oncolytic Virus-treated Mice Mol Ther 2013 21: 913; 10.1038/mt.2013.48 Full Text Submit to Molecular Therapy Molecular Therapy (MT) is dedicated to publishing important peer-reviewed research and cutting-edge reviews and promoting the sciences in genetics, medicine and biotechnology.  Find out more about MT and the benefits of submitting to the journal.   Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Molecular Therapy. 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