Clinical Pharmacology and Therapeutics - Table of Contents alert Volume 93 Issue 4

TABLE OF CONTENTS Volume 93, Issue 4 (April 2013) In this issue In This Issue Editorial News & Views Perspectives Translation Development Regulation & Use CPIC Update Clinical Trial Reviews Research Corrigenda Also new AOP Sign up for CPT: Pharmacometrics & Systems Pharmacology e-alerts Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement Clinical Pharmacology & Therapeutics Accepting: - Clinical trials - Original research articles - Letters to the Editor - Reviews   In This Issue Top In This Issue Clin Pharmacol Ther 2013 93: 283; 10.1038/clpt.2013.31 Full Text Editorial Top Systems-Based Discovery Advances Drug Development S A Waldman and A Terzic Clin Pharmacol Ther 2013 93: 285-287; 10.1038/clpt.2013.21 Abstract | Full Text News & Views Top Highlights Clin Pharmacol Ther 2013 93: 288-289; 10.1038/clpt.2013.30 Full Text ASCPT News Clin Pharmacol Ther 2013 93: 290-293; 10.1038/clpt.2013.18 Full Text Perspectives Top COMMENTARIES A Network-Heuristic Approach to Improve the Impact of Genomic Data on Drug Discovery A D Trister and E S Huang Clin Pharmacol Ther 2013 93: 295-297; 10.1038/clpt.2012.246 Abstract | Full Text It Is Important Research, but Why Is It Necessary? R L Woosley Clin Pharmacol Ther 2013 93: 297-299; 10.1038/clpt.2013.15 Abstract | Full Text Phenotypic vs. Target-Based Drug Discovery for First-in-Class Medicines D C Swinney Clin Pharmacol Ther 2013 93: 299-301; 10.1038/clpt.2012.236 Abstract | Full Text If You Don’t Know Where You Are Going, You Can’t Tell If You Have Arrived: Defining Goals for Drug Safety Announcements A J J Wood Clin Pharmacol Ther 2013 93: 302-303; 10.1038/clpt.2012.265 Abstract | Full Text Model-Based Drug Development in Oncology: What’s Next? R Bruno, F Mercier and L Claret Clin Pharmacol Ther 2013 93: 303-305; 10.1038/clpt.2013.8 Abstract | Full Text LETTERS TO THE EDITOR Pretransplantation Pharmacokinetic Assessments to Predict Posttransplantation Dosing Requirements in renal Transplant Recipients: What Is Known? E van Maarseveen and A D van Zuilen Clin Pharmacol Ther 2013 93: 306-307; advance online publication, October 24, 2012; 10.1038/clpt.2012.214 Full Text Response to “Pretransplantation Pharmacokinetic Assessments to Predict Posttransplantation Dosing Requirements in Renal Transplant Recipients: What Is Known?” H de Jonge and D R Kuypers Clin Pharmacol Ther 2013 93: 307-308; advance online publication, December 6, 2012; 10.1038/clpt.2012.234 Full Text Translation Top Functionalizing Genomic Data for Personalization of Medicine C H Benes Clin Pharmacol Ther 2013 93: 309-311; advance online publication, November 7, 2012; 10.1038/clpt.2012.219 Full Text Development Top Targeting Chromatin Readers L I James and S V Frye Clin Pharmacol Ther 2013 93: 312-314; advance online publication, January 17, 2013; 10.1038/clpt.2013.6 Abstract | Full Text The Continuum of Comparability Extends to Biosimilarity: How Much Is Enough and What Clinical Data Are Necessary? Open M McCamish and G Woollett Clin Pharmacol Ther 2013 93: 315-317; advance online publication, January 25, 2013; 10.1038/clpt.2013.17 Full Text Regulation & Use Top PRACTICE Patent Eligibility of Induced Pluripotent Stem Cell Theranostics K Triller Vrtovec and B Vrtovec Clin Pharmacol Ther 2013 93: 318-320; advance online publication, January 22, 2013; 10.1038/clpt.2013.11 Full Text Cardiovascular Disease Prevention: Matching Evidence-Based Algorithms With Individualized Care R Madanieh, R K Hasan, O F Anusionwu, R S Blumenthal and M J Blaha Clin Pharmacol Ther 2013 93: 321-323; advance online publication, January 16, 2013; 10.1038/clpt.2013.3 Abstract | Full Text CPIC Update Top Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing: 2013 Update M V Relling, E E Gardner, W J Sandborn, K Schmiegelow, C-H Pui, S W Yee, C M Stein, M Carrillo, W E Evans, J K Hicks, M Schwab and T E Klein Clin Pharmacol Ther 2013 93: 324-325; advance online publication, January 17, 2013; 10.1038/clpt.2013.4 Full Text Clinical Trial Top Contribution of Endogenous Bradykinin to Fibrinolysis, Inflammation, and Blood Product Transfusion Following Cardiac Surgery: A Randomized Clinical Trial J M Balaguer, C Yu, J G Byrne, S K Ball, M R Petracek, N J Brown and M Pretorius Clin Pharmacol Ther 2013 93: 326-334; advance online publication, December 24, 2012; 10.1038/clpt.2012.249 Abstract | Full Text Reviews Top Computational Drug Repositioning: From Data to Therapeutics M R Hurle, L Yang, Q Xie, D K Rajpal, P Sanseau and P Agarwal Clin Pharmacol Ther 2013 93: 335-341; advance online publication, January 15, 2013; 10.1038/clpt.2013.1 Abstract | Full Text Balancing Societal Needs and Regulatory Certainty: The Case Study of Peramivir in Japan T Tominaga, Y Ando, N Nagai, J Sato and T Kondo Clin Pharmacol Ther 2013 93: 342-344; advance online publication, January 15, 2013; 10.1038/clpt.2012.268 Abstract | Full Text Research Top ARTICLES Estimation of Renal Cell Carcinoma Treatment Effects From Disease Progression Modeling M L Maitland, K Wu, M R Sharma, Y Jin, S P Kang, W M Stadler, T G Karrison, M J Ratain and R R Bies Clin Pharmacol Ther 2013 93: 345-351; advance online publication, December 27, 2012; 10.1038/clpt.2012.263 Abstract | Full Text Clinical Proof-of-Concept Study With MSDC-0160, a Prototype mTOT-Modulating Insulin Sensitizer Open J R Colca, J T VanderLugt, W J Adams, A Shashlo, W G McDonald, J Liang, R Zhou and D G Orloff Clin Pharmacol Ther 2013 93: 352-359; advance online publication, January 18, 2013; 10.1038/clpt.2013.10 Abstract | Full Text When Direct Health-Care Professional Communications Have an Impact on Inappropriate and Unsafe Use of Medicines K C Reber, S Piening, J E Wieringa, S M J M Straus, J M Raine, P A de Graeff, F M Haaijer-Ruskamp and P G M Mol Clin Pharmacol Ther 2013 93: 360-365; advance online publication, December 27, 2012; 10.1038/clpt.2012.262 Abstract | Full Text Corrigenda Top Corrigendum: Economic and Technological Drivers of Generic Sterile Injectable Drug Shortages Clin Pharmacol Ther 2013 93: 366; 10.1038/clpt.2013.20 Full Text Corrigendum: Review of In Vitro Transporter Data in Recently Approved New Drug Applications Clin Pharmacol Ther 2013 93: 366; 10.1038/clpt.2013.25 Full Text Corrigendum: Prospects for Treatment of Latent HIV Clin Pharmacol Ther 2013 93: 366; 10.1038/clpt.2013.19 Full Text Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Clinical Pharmacology & Therapeutics. 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