The EDGE

Exploiting inflammation for therapeutic gain in pancreatic cancer

C W Steele, N B Jamieson, T R J Evans, C J McKay, O J Sansom, J P Morton and C R Carter

Br J Cancer 2013 108: 997-1003; advance online publication, February 5, 2013; 10.1038/bjc.2013.24

Clinical Studies

Implications of sperm banking for health-related quality of life up to 1 year after cancer diagnosis

A Pacey, H Merrick, E Arden-Close, K Morris, R Rowe, D Stark and C Eiser

Br J Cancer 2013 108: 1004-1011; advance online publication, March 7, 2013; 10.1038/bjc.2013.57

Short-term psychological impact of the BRCA1/2 test result in women with breast cancer according to their perceived probability of genetic predisposition to cancer

A Brédart, J L Kop, A DePauw, O Caron, S Sultan, D Leblond, A Fajac, B Buecher, M Gauthier-Villars, C Noguès, C Flahault, D Stoppa-Lyonnet and S Dolbeault

Br J Cancer 2013 108: 1012-1020; advance online publication, March 5, 2013; 10.1038/bjc.2012.599

Ridaforolimus as a single agent in advanced endometrial cancer: results of a single-arm, phase 2 trial

N Colombo, D S McMeekin, P E Schwartz, C Sessa, P A Gehrig, R Holloway, P Braly, D Matei, A Morosky, P F Dodion, M H Einstein and F Haluska

Br J Cancer 2013 108: 1021-1026; advance online publication, February 12, 2013; 10.1038/bjc.2013.59

A randomised double-blind placebo-controlled phase II study of AGI004 for control of chemotherapy-induced diarrhoea

V M Coyle, D Lungulescu, C Toganel, A Niculescu, S Pop, T Ciuleanu, C Cebotaru, J Devane, M Martin and R H Wilson

Br J Cancer 2013 108: 1027-1033; advance online publication, March 5, 2013; 10.1038/bjc.2013.35

Sarcopenia and body mass index predict sunitinib-induced early dose-limiting toxicities in renal cancer patients

O Huillard, O Mir, M Peyromaure, C Tlemsani, J Giroux, P Boudou-Rouquette, S Ropert, N Barry Delongchamps, M Zerbib and F Goldwasser

Br J Cancer 2013 108: 1034-1041; advance online publication, March 5, 2013; 10.1038/bjc.2013.58

Biology of primary breast cancer in older women treated by surgery: with correlation with long-term clinical outcome and comparison with their younger counterparts

B M Syed, A R Green, E C Paish, D Soria, J Garibaldi, L Morgan, D A L Morgan, I O Ellis and K L Cheung

Br J Cancer 2013 108: 1042-1051; advance online publication, March 5, 2013; 10.1038/bjc.2012.601

Biomarker results from the AVADO phase 3 trial of first-line bevacizumab plus docetaxel for HER2-negative metastatic breast cancer

D W Miles, S L de Haas, L Y Dirix, G Romieu, A Chan, X Pivot, P Tomczak, L Provencher, J Cortés, P R Delmar and S J Scherer

Br J Cancer 2013 108: 1052-1060; advance online publication, February 19, 2013; 10.1038/bjc.2013.69

A first-in-class, first-in-human, phase I trial of p28, a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in patients with advanced solid tumours

M A Warso, J M Richards, D Mehta, K Christov, C Schaeffer, L Rae Bressler, T Yamada, D Majumdar, S A Kennedy, C W Beattie and T K Das Gupta

Br J Cancer 2013 108: 1061-1070; advance online publication, February 28, 2013; 10.1038/bjc.2013.74

Translational Therapeutics

Prevalence of potential drug–drug interactions in cancer patients treated with oral anticancer drugs

R W F van Leeuwen, D H S Brundel, C Neef, T van Gelder, R H J Mathijssen, D M Burger and F G A Jansman

Br J Cancer 2013 108: 1071-1078; advance online publication, February 14, 2013; 10.1038/bjc.2013.48

Marked improvement of cytotoxic effects induced by docetaxel on highly metastatic and androgen-independent prostate cancer cells by downregulating macrophage inhibitory cytokine-1

M Mimeault, S L Johansson and S K Batra

Br J Cancer 2013 108: 1079-1091; advance online publication, February 28, 2013; 10.1038/bjc.2012.484

Early immunisation with dendritic cells after allogeneic bone marrow transplantation elicits graft vs tumour reactivity

V Gigi, J Stein, N Askenasy, I Yaniv and S Ash

Br J Cancer 2013 108: 1092-1099; 10.1038/bjc.2013.39

Molecular Diagnostics

High MET expression is an adverse prognostic factor in patients with triple-negative breast cancer

F Zagouri, Z Bago-Horvath, F Rössler, A Brandstetter, R Bartsch, C A Papadimitriou, C Dimitrakakis, A Tsigginou, I Papaspyrou, A Giannos, M-A Dimopoulos and M Filipits

Br J Cancer 2013 108: 1100-1105; advance online publication, February 19, 2013; 10.1038/bjc.2013.31

Radiation-induced non-targeted response in vivo: role of the TGFβ-TGFBR1-COX-2 signalling pathway

Y Chai, R K K Lam, G M Calaf, H Zhou, S Amundson and T K Hei

Br J Cancer 2013 108: 1106-1112; advance online publication, February 14, 2013; 10.1038/bjc.2013.53

Apical MUC1 expression revealed on the foveolar epithelium in H. pylori gastritis

M Rashid, A S Teixeira, U Qureshi, S P Pereira, M R Novelli and D M Swallow

Br J Cancer 2013 108: 1113-1118; advance online publication, February 14, 2013; 10.1038/bjc.2013.54

NY-ESO-1 antibody as a novel tumour marker of gastric cancer

S Fujiwara, H Wada, J Kawada, R Kawabata, T Takahashi, J Fujita, T Hirao, K Shibata, Y Makari, S Iijima, H Nishikawa, A A Jungbluth, Y Nakamura, Y Kurokawa, M Yamasaki, H Miyata, K Nakajima, S Takiguchi, E Nakayama, M Mori and Y Doki

Br J Cancer 2013 108: 1119-1125; advance online publication, February 12, 2013; 10.1038/bjc.2013.51

VEGF and VEGFR polymorphisms affect clinical outcome in advanced renal cell carcinoma patients receiving first-line sunitinib

M Scartozzi, M Bianconi, L Faloppi, C Loretelli, A Bittoni, M Del Prete, R Giampieri, E Maccaroni, S Nicoletti, L Burattini, D Minardi, G Muzzonigro, R Montironi and S Cascinu

Br J Cancer 2013 108: 1126-1132; advance online publication, November 29, 2012; 10.1038/bjc.2012.501

miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis

R I McCormick, C Blick, J Ragoussis, J Schoedel, D R Mole, A C Young, P J Selby, R E Banks and A L Harris

Br J Cancer 2013 108: 1133-1142; advance online publication, February 28, 2013; 10.1038/bjc.2013.56

ING1b-inducible microRNA203 inhibits cell proliferation

J Chen, U M Tran, U Rajarajacholan, S Thalappilly and K Riabowol

Br J Cancer 2013 108: 1143-1148; advance online publication, March 5, 2013; 10.1038/bjc.2013.50

Assessing the value of matrix metalloproteinase 9 (MMP9) in improving the appropriateness of referrals for colorectal cancer

S Damery, L Nichols, R Holder, S T Ward, S Warmington, S Wilson, M J Wakelam, J James and T Ismail

Br J Cancer 2013 108: 1149-1156; advance online publication, February 7, 2013; 10.1038/bjc.2013.49

HPV infection in squamous cell carcinomas arising from different mucosal sites of the head and neck region. Is p16 immunohistochemistry a reliable surrogate marker?

F Bussu, M Sali, R Gallus, V G Vellone, G F Zannoni, R Autorino, N Dinapoli, R Santangelo, R Martucci, C Graziani, F Miccichè, G Almadori, J Galli, G Delogu, M Sanguinetti, G Rindi, V Valentini and G Paludetti

Br J Cancer 2013 108: 1157-1162; advance online publication, February 12, 2013; 10.1038/bjc.2013.55

Epidemiology

Fecal microbiota diversity in survivors of adolescent/young adult Hodgkin lymphoma: a study of twins

W Cozen, G Yu, M H Gail, V K Ridaura, B N Nathwani, A E Hwang, A S Hamilton, T M Mack, J I Gordon and J J Goedert

Br J Cancer 2013 108: 1163-1167; advance online publication, February 26, 2013; 10.1038/bjc.2013.60

Flavonoid intake and risk of pancreatic cancer in the National Institutes of Health-AARP Diet and Health Study Cohort

H Arem, G Bobe, J Sampson, A F Subar, Y Park, H Risch, A Hollenbeck, S T Mayne and R Z Stolzenberg-Solomon

Br J Cancer 2013 108: 1168-1172; advance online publication, January 8, 2013; 10.1038/bjc.2012.584

The interaction between smoking status and highly active antiretroviral therapy (HAART) use on the risk of Kaposi’s sarcoma (KS) in a cohort of HIV-infected men

H N Luu, E S Amirian and M E Scheurer

Br J Cancer 2013 108: 1173-1177; advance online publication, February 19, 2013; 10.1038/bjc.2013.75

Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer

J C Wilson, L J Murray, C M Hughes, A Black and L A Anderson

Br J Cancer 2013 108: 1178-1181; advance online publication, February 28, 2013; 10.1038/bjc.2013.73

Diabetes mellitus and risk of hepatocellular carcinoma: findings from the Singapore Chinese Health Study

W-P Koh, R Wang, A Jin, M C Yu and J-M Yuan

Br J Cancer 2013 108: 1182-1188; advance online publication, January 31, 2013; 10.1038/bjc.2013.25

Use of low-dose aspirin and non-aspirin nonsteroidal anti-inflammatory drugs and risk of glioma: a case–control study

D Gaist, L A García-Rodríguez, H T Sørensen, J Hallas and S Friis

Br J Cancer 2013 108: 1189-1194; advance online publication, February 28, 2013; 10.1038/bjc.2013.87

Breast cancer survival and stage at diagnosis in Australia, Canada, Denmark, Norway, Sweden and the UK, 2000-2007: a population-based study

S Walters, C Maringe, J Butler, B Rachet, P Barrett-Lee, J Bergh, J Boyages, P Christiansen, M Lee, F Wärnberg, C Allemani, G Engholm, T Fornander, M L Gjerstorff, T B Johannesen, G Lawrence, C E McGahan, R Middleton, J Steward, E Tracey, D Turner, M A Richards and M P Coleman The ICBP Module 1 Working Group²⁰

Br J Cancer 2013 108: 1195-1208; advance online publication, February 28, 2013; 10.1038/bjc.2013.6

Letters to the Editor

Cost-effectiveness of population-based screening for colorectal cancer

J F O'Mahony

Br J Cancer 2013 108: 1209-1210; advance online publication, February 7, 2013; 10.1038/bjc.2012.490

Reply: cost-effectiveness of population-based screening for colorectal cancer

L Sharp, C Walsh, S Whyte, L Tilson, A O'Ceilleachair, C Usher, P Tappenden, J Chilcott, A Staines, M Barry and H Comber

Br J Cancer 2013 108: 1211-1212; advance online publication, February 7, 2013; 10.1038/bjc.2012.491

Comment on ‘cancer incidence in the United Kingdom: projections to the year 2030’

S E Oliver, E Roman, S Crouch, E Bolton and B Ferguson

Br J Cancer 2013 108: 1213-1214; advance online publication, February 21, 2013; 10.1038/bjc.2013.71

Reply to ‘Comment on Cancer incidence in the United Kingdom: projections to the year 2030’

A S Ahmad, D M Parkin and P D Sasieni

Br J Cancer 2013 108: 1215-1217; advance online publication, February 21, 2013; 10.1038/bjc.2013.72

Misunderstandings in the misconception on the use of pack-years in analysis of smoking

J H Lubin and N E Caporaso

Br J Cancer 2013 108: 1218-1220; advance online publication, February 28, 2013; 10.1038/bjc.2013.76

Reply: Misunderstandings in the misconception on the use of pack-years in analysis of smoking

J Peto

Br J Cancer 2013 108: 1221; advance online publication, February 28, 2013; 10.1038/bjc.2013.77

Corrigenda

An examination, with a meta-analysis, of studies of childhood leukaemia in relation to population mixing

L J Kinlen

Br J Cancer 2013 108: 1222; 10.1038/bjc.2013.110

Cancer incidence among the south Asian and non-south Asian population under 30 years of age in Yorkshire, UK

M van Laar, P A McKinney, R C Parslow, A Glaser, S E Kinsey, I J Lewis, S V Picton, M Richards, G Shenton, D Stark, P Norman and R G Feltbower

Br J Cancer 2013 108: 1223-1224; 10.1038/bjc.2013.67