Clinical Pharmacology and Therapeutics - Table of Contents alert Volume 93 Issue 2

Advertisement Myriad RBM's Comprehensive Protein Biomarker Solutions, helping turn biomarker studies into Biomarker Breakthroughs. From concept through clinical trial, Myriad RBM has the biomarkers, the platform and the expertise to guide your biomarker strategy. Click Here to learn more. TABLE OF CONTENTS Volume 93, Issue 2 (February 2013) In this issue In This Issue Editorial News & Views Perspectives Discovery & Development Clinical Trial State of the Art Research Also new AOP Sign up for CPT: Pharmacometrics & Systems Pharmacology e-alerts Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement Web Focus: Induced Pluripotent Stem Cells Congratulations Dr. Shinya Yamanaka on winning the 2012 Nobel Prize in Physiology or Medicine for the discovery that mature cells can be reprogrammed to become pluripotent. Get to know the outstanding research of Dr. Yamanaka and his colleagues, in this dedicated web focus featuring a collection of their articles on iPS technology.   In This Issue Top In This Issue Clin Pharmacol Ther 2013 93: 131; 10.1038/clpt.2012.239 Full Text Editorial Top Drug Shortages in the United States: A Critical Evaluation of Root Causes and the Need for Action D K Gupta and S-M Huang Clin Pharmacol Ther 2013 93: 133-135; 10.1038/clpt.2012.229 Abstract | Full Text News & Views Top Highlights Clin Pharmacol Ther 2013 93: 136-137; 10.1038/clpt.2012.238 Full Text ASCPT News Clin Pharmacol Ther 2013 93: 138-142; 10.1038/clpt.2012.226 Full Text Perspectives Top COMMENTARIES Pharmacy Benefit Managers and Their Obligations During Serious Prescription Drug Shortages J R Teagarden and R S Epstein Clin Pharmacol Ther 2013 93: 143-145; 10.1038/clpt.2012.224 Abstract | Full Text Call to Action: Finding Solutions for the Drug Shortage Crisis in the United States E R Fox and L S Tyler Clin Pharmacol Ther 2013 93: 145-147; 10.1038/clpt.2012.225 Abstract | Full Text LETTERS TO THE EDITOR Physiologically Based Pharmacokinetic Modeling at the Extremes of Age C Johnston, C M Kirkpatrick, A J McLachlan and S N Hilmer Clin Pharmacol Ther 2013 93: 148; advance online publication, November 21, 2012; 10.1038/clpt.2012.176 Full Text Response to “Physiologically Based Pharmacokinetic Modeling at the Extremes of Age” O Della Casa Alberighi, J S Barrett, S Läer and B Meibohm Clin Pharmacol Ther 2013 93: 149; advance online publication, November 28, 2012; 10.1038/clpt.2012.200 Full Text The Epigenome in Personalized Medicine J Peedicayil Clin Pharmacol Ther 2013 93: 149-150; advance online publication, December 12, 2012; 10.1038/clpt.2012.177 Full Text Drug Interactions Produced by Proton Pump Inhibitors: Not Simply a pH Effect J M Mullin and J J Schrogie Clin Pharmacol Ther 2013 93: 150; advance online publication, November 21, 2012; 10.1038/clpt.2012.182 Full Text Response to “Drug Interactions Produced by Proton Pump Inhibitors: Not Simply a pH Effect” N R Budha, L Z Benet and J A Ware Clin Pharmacol Ther 2013 93: 151; advance online publication, October 12, 2012; 10.1038/clpt.2012.206 Full Text The Link Between Pharmacodynamics and Physiologically Based Pharmacokinetic Models V Perera, M A Elmeliegy, G Rao and A Forrest Clin Pharmacol Ther 2013 93: 151-152; advance online publication, January 9, 2013; 10.1038/clpt.2012.178 Full Text Response to “The Link Between Pharmacodynamics and Physiologically Based Pharmacokinetic Models” A Rostami-Hodjegan Clin Pharmacol Ther 2013 93: 152; advance online publication, November 5, 2012; 10.1038/clpt.2012.216 Full Text Discovery & Development Top CPIC GUIDELINES Clinical Pharmacogenetics Implementation Consortium Guidelines for Human Leukocyte Antigen-B Genotype and Allopurinol Dosing M S Hershfield, J T Callaghan, W Tassaneeyakul, T Mushiroda, C F Thorn, T E Klein and M T M Lee Clin Pharmacol Ther 2013 93: 153-158; advance online publication, October 17, 2012; 10.1038/clpt.2012.209 Full Text DEVELOPMENT Is This the Dose for You?: The Role of Modeling S-M Huang, A Bhattaram, N Mehrotra and Y Wang Clin Pharmacol Ther 2013 93: 159-162; advance online publication, November 19, 2012; 10.1038/clpt.2012.228 Full Text Clinical Trial Top First-Time-in-Human Study With GSK249320, a Myelin-Associated Glycoprotein Inhibitor, in Healthy Volunteers B Abila, E Cunningham and M Simeoni Clin Pharmacol Ther 2013 93: 163-169; advance online publication, November 16, 2012; 10.1038/clpt.2012.227 Abstract | Full Text State of the Art Top Economic and Technological Drivers of Generic Sterile Injectable Drug Shortages J Woodcock and M Wosinska Clin Pharmacol Ther 2013 93: 170-176; advance online publication, November 7, 2012; 10.1038/clpt.2012.220 Abstract | Full Text Using Genetics to Enable Studies on the Prevention of Alzheimer’s Disease D G Crenshaw, W K Gottschalk, M W Lutz, I Grossman, A M Saunders, J R Burke, K A Welsh-Bohmer, S K Brannan, D K Burns and A D Roses Clin Pharmacol Ther 2013 93: 177-185; advance online publication, November 7, 2012; 10.1038/clpt.2012.222 Abstract | Full Text Research Top ARTICLES The Effect of Novel Promoter Variants in MATE1 and MATE2 on the Pharmacokinetics and Pharmacodynamics of Metformin S L Stocker, K M Morrissey, S W Yee, R A Castro, L Xu, A Dahlin, A H Ramirez, D M Roden, R A Wilke, C A McCarty, R L Davis, C M Brett and K M Giacomini Clin Pharmacol Ther 2013 93: 186-194; advance online publication, October 17, 2012; 10.1038/clpt.2012.210 Abstract | Full Text CYP2C19*17 Gain-of-Function Polymorphism Is Associated With Peptic Ulcer Disease C O Musumba, A Jorgensen, L Sutton, D Van Eker, E Zhang, N O’Hara, D F Carr, D M Pritchard and M Pirmohamed Clin Pharmacol Ther 2013 93: 195-203; advance online publication, October 26, 2012; 10.1038/clpt.2012.215 Abstract | Full Text Inclusion of Pediatric Samples in an Opt-Out Biorepository Linking DNA to De-Identified Medical Records: Pediatric BioVU T L McGregor, S L Van Driest, K B Brothers, E A Bowton, L J Muglia and D M Roden Clin Pharmacol Ther 2013 93: 204-211; advance online publication, November 21, 2012; 10.1038/clpt.2012.230 Abstract | Full Text   Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Clinical Pharmacology & Therapeutics. 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