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|  | | 03 July 2012 |  | | Featured image: |  |  |  | | Dawson et al. reveal the structure of acid-sensing ion channel 1 bound to psalmotoxin 1. |
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|  | | | | | Latest Articles | View all Articles | | | |  | ER-localized auxin transporter PIN8 regulates auxin homeostasis and male gametophyte development in Arabidopsis OPEN |  | | Zhaojun Ding, Bangjun Wang, Ignacio Moreno, Nikoleta Dupláková, Sibu Simon, Nicola Carraro, Jesica Reemmer, Aleš Pěnčík, Xu Chen, Ricardo Tejos, Petr Skůpa, Stephan Pollmann, Jozef Mravec, Jan Petrášek, Eva Zažímalová, David Honys, Jakub Rolčík, Angus Murphy, Ariel Orellana, Markus Geisler and Jiří Friml |  | | Plant hormones, such as auxin, coordinate plant development. In this study, an auxin transporter—PIN8—that is expressed in the male gametophyte of Arabidopsis thaliana, is found to regulate cellular homoeostasis and maintain optimal levels of auxin for pollen development. |  | | 03 Jul | Nat Commun 3:941 doi:10.1038/ncomms1941 (2012) |  | | Biological sciences Plant sciences |  | Abstract | Full Text | PDF (1,033 kB) | Supplementary Information |

 | Stereoselectivity and electrostatics in charge-transfer Mn- and Cs-TCNQ4 networks on Ag(100) |  | | Nasiba Abdurakhmanova, Andrea Floris, Tzu-Chun Tseng, Alessio Comisso, Sebastian Stepanow, Alessandro De Vita and Klaus Kern |  | | The crystallization of a racemate on a surface can lead to crystals with a unit cell containing both enantiomers, or to the separation of enantiomers into crystals of single-handedness. This study shows that manganese co-absorbed with a quinone derivative leads to achiral islands, while co-absorption with caesium gives chiral islands. |  | | 03 Jul | Nat Commun 3:940 doi:10.1038/ncomms1942 (2012) |  | | Chemical sciences Nanotechnology Physical chemistry |  | |  | Abstract | Full Text | PDF (1,176 kB) | Supplementary Information |

 | A halictid bee with sympatric solitary and eusocial nests offers evidence for Hamilton's rule |  | | Norihiro Yagi and Eisuke Hasegawa |  | | Theory states that sterile worker bees compensate for a lack of direct fitness by contributing to the nest, but testing this has been difficult. Here, for the solitary and eusocial bee L. baleicum, the inclusive fitness of an eusocial worker is higher than that of a solitary female, satisfying the rule in the field. |  | | 03 Jul | Nat Commun 3:939 doi:10.1038/ncomms1939 (2012) |  | | Biological sciences Ecology Evolution |  | | Zoology |  | | Abstract | Full Text | PDF (480 kB) |

 | Robust spin crossover and memristance across a single molecule OPEN |  | | Toshio Miyamachi, Manuel Gruber, Vincent Davesne, Martin Bowen, Samy Boukari, Loïc Joly, Fabrice Scheurer, Guillaume Rogez, Toyo Kazu Yamada, Philippe Ohresser, Eric Beaurepaire and Wulf Wulfhekel |  | | Switches made up of single molecules form the basis for the concept of molecular electronics. Miyamachi et al. demonstrate that an iron-based spin crossover molecule can be switched between different spin states, provided it is decoupled from a metallic substrate by a thin insulating layer. |  | | 03 Jul | Nat Commun 3:938 doi:10.1038/ncomms1940 (2012) |  | | Physical sciences Materials science |  | | Nanotechnology |  | Abstract | Full Text | PDF (907 kB) | Supplementary Information |

 | Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins |  | | Clement T.Y. Chan, Yan Ling Joy Pang, Wenjun Deng, I. Ramesh Babu, Madhu Dyavaiah, Thomas J. Begley and Peter C. Dedon |  | | In response to stress, yeast cells selectively translate proteins that can enhance cell survival. In this study, the authors find that tRNALEU(CAA) in yeast cells is modified in response to oxidative stress by a methyltransferase and this results in the selective translation of the mRNA for these genes. |  | | 03 Jul | Nat Commun 3:937 doi:10.1038/ncomms1938 (2012) |  | | Biological sciences Biochemistry |  | | Molecular biology |  | Abstract | Full Text | PDF (806 kB) | Supplementary Information |

 | Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1 OPEN |  | | Roger J.P. Dawson, Jörg Benz, Peter Stohler, Tim Tetaz, Catherine Joseph, Sylwia Huber, Georg Schmid, Daniela Hügin, Pascal Pflimlin, Gerd Trube, Markus G. Rudolph, Michael Hennig and Armin Ruf |  | | The activity of the Acid sensing ion channel 1, ASIC1, can be modulated by the gating modifier Psalmotoxin 1 but the molecular mechanism is unclear. Dawson et al. report the structure of chicken ASIC1 bound to Psalmotoxin 1 and find that the toxin locks two regulatory regions of the channel into a desensitized conformation. |  | | 03 Jul | Nat Commun 3:936 doi:10.1038/ncomms1917 (2012) |  | | Biological sciences Biochemistry |  | | Molecular biology |  | Abstract | Full Text | PDF (620 kB) | Supplementary Information |

 | Field-directed sputter sharpening for tailored probe materials and atomic-scale lithography |  | | S.W. Schmucker, N. Kumar, J.R. Abelson, S.R. Daly, G.S. Girolami, M.R. Bischof, D.L. Jaeger, R.F. Reidy, B.P. Gorman, J. Alexander, J.B. Ballard, J.N. Randall and J.W. Lyding |  | | Scanning probe microscopy and related techniques rely on the availability of very sharp tips. Here, a sharpening technique based on field-directed sputtering is demonstrated, resulting in ultrasharp metallic tips for use in scanning tunnelling microscopy as well as atomic-scale lithographic experiments. |  | | 03 Jul | Nat Commun 3:935 doi:10.1038/ncomms1907 (2012) |  | | Physical sciences Applied physics |  | | Atomic and molecular physics Nanotechnology |  | |  | Abstract | Full Text | PDF (718 kB) | Supplementary Information |

 
 | Absorption imaging of a single atom |  | | Erik W. Streed, Andreas Jechow, Benjamin G. Norton and David Kielpinski |  | | Absorption imaging relies on the capture of photons by an object to create intensity contrasts, allowing for the visualization of small quantum systems. Streed et al. demonstrate the first absorption imaging of an isolated ytterbium ion, with contrast at the limit of semiclassical theory. |  | | 03 Jul | Nat Commun 3:933 doi:10.1038/ncomms1944 (2012) |  | | Physical sciences Atomic and molecular physics |  | | Optical physics |  | | Abstract | Full Text | PDF (661 kB) |

 | Tunable conductivity threshold at polar oxide interfaces |  | | M.L. Reinle-Schmitt, C. Cancellieri, D. Li, D. Fontaine, M. Medarde, E. Pomjakushina, C.W. Schneider, S. Gariglio, Ph. Ghosez, J.-M. Triscone and P.R. Willmott |  | | The SrTiO3/LaAlO3 system is widely studied because it forms a two-dimensional electron gas at the interface. This study investigates the effects of diluting the LaAlO3 layer with SrTiO3, and finds that the threshold thickness required for the onset of conductivity scales inversely with the fraction of LaAlO3, suggesting an intrinsic origin for the electron gas. |  | | 03 Jul | Nat Commun 3:932 doi:10.1038/ncomms1936 (2012) |  | | Physical sciences Condensed matter |  | | Materials science |  | | Abstract | Full Text | PDF (602 kB) |

 | Electronic origin of high-temperature superconductivity in single-layer FeSe superconductor |  | | Defa Liu, Wenhao Zhang, Daixiang Mou, Junfeng He, Yun-Bo Ou, Qing-Yan Wang, Zhi Li, Lili Wang, Lin Zhao, Shaolong He, Yingying Peng, Xu Liu, Chaoyu Chen, Li Yu, Guodong Liu, Xiaoli Dong, Jun Zhang, Chuangtian Chen, Zuyan Xu, Jiangping Hu, Xi Chen, Xucun Ma, Qikun Xue and X.J. Zhou |  | | The exact mechanism for superconductivity in iron-based superconductors remains elusive, but is thought to involve complex interactions between many orbitals. Using angle-resolved photoelectron spectroscopy, Liu et al. report the electronic structure of the single-layer parent compound FeSe. |  | | 03 Jul | Nat Commun 3:931 doi:10.1038/ncomms1946 (2012) |  | | Physical sciences Condensed matter |  | | Materials science |  | |  | | Abstract | Full Text | PDF (605 kB) |

 | Towards a quantum representation of the ampere using single electron pumps |  | | S.P. Giblin, M. Kataoka, J.D. Fletcher, P. See, T.J.B.M. Janssen, J.P. Griffiths, G.A.C. Jones, I. Farrer and D.A. Ritchie |  | | Single electron pumps have been proposed as potential candidates for redefining the ampere. This study reports measurements of the quantized current flowing through a semiconductor electron pump with a precision that makes a substantial step towards establishing a direct metric for electrical currents. |  | | 03 Jul | Nat Commun 3:930 doi:10.1038/ncomms1935 (2012) |  | | Physical sciences Condensed matter |  | | Nanotechnology |  | Abstract | Full Text | PDF (682 kB) | Supplementary Information |

 | In silico method for modelling metabolism and gene product expression at genome scale OPEN |  | | Joshua A. Lerman, Daniel R. Hyduke, Haythem Latif, Vasiliy A. Portnoy, Nathan E. Lewis, Jeffrey D. Orth, Alexandra C. Schrimpe-Rutledge, Richard D. Smith, Joshua N. Adkins, Karsten Zengler and Bernhard O. Palsson |  | | To describe the biochemical composition of an organism multiple data sets must be combined and this information can then be used for in silico analysis. By combining metabolism and transcription data, Lerman et al. discovered new regulons and improved the gene annotation for the simple organism Thermotoga maritima. |  | | 03 Jul | Nat Commun 3:929 doi:10.1038/ncomms1928 (2012) |  | | Biological sciences Bioinformatics |  | | Systems biology |  | Abstract | Full Text | PDF (988 kB) | Supplementary Information |
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