Nature Communications - 10 July 2012

Weekly Content Alert 10 July 2012 Featured image: Zhang et al. build chiral metamaterials whose handedness can be switched between left and right using laser pulses. Latest content: Articles Journal homepage Recommend to library Web feed   Advertisement Nature Structural & Molecular Biology FOCUS ON TRANSLATIONAL CONTROL Translational control has become a major focus of attention and research activity. The identification of a myriad of new factors and genome-wide targets as well as recent insights into eukaryotic ribosomes, translation initiation and control mechanisms will be discussed in four Reviews and one Perspective by leaders in the field. Access the Focus online: http://www.nature.com/nsmb/focus/translation     Latest Articles View all Articles     The CD4+ T-cell help signal is transmitted from APC to CD8+ T-cells via CD27–CD70 interactions Sonia Feau, Zacarias Garcia, Ramon Arens, Hideo Yagita, Jannie Borst and Stephen P. Schoenberger CD8+ memory cytotoxic T lymphocytes need help from CD4+ T cells to undergo secondary expansion but the mechanisms of help are not fully understood. Here, it is shown that, after activation by CD4+ T cells, antigen-presenting cells activate CD8+ T cells via the CD70/CD27 co-stimulatory pathway. 10 Jul | Nat Commun 3:948 doi:10.1038/ncomms1948 (2012) Biological sciences Immunology  Abstract | Full Text | PDF (848 kB) Exploring the wavefront of hard X-ray free-electron laser radiation Simon Rutishauser, Liubov Samoylova, Jacek Krzywinski, Oliver Bunk, Jan Grünert, Harald Sinn, Marco Cammarata, David M. Fritz and Christian David X-ray free-electron lasers offer a wealth of possibilities for future diffraction studies, but variations in successive pulses mean the wavefront is not well defined. Rutishauser et al. use grating interferometry to characterize the wavefronts shot to shot, both in situ and under operating conditions. 10 Jul | Nat Commun 3:947 doi:10.1038/ncomms1950 (2012) Physical sciences Optical physics  Abstract | Full Text | PDF (645 kB) | Supplementary Information The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity Kehui Xiang, James L. Manley and Liang Tong Regulator of transcription 1, Rtr1, has been proposed to function as an RNA polymerase II phosphatase. Here, the lack of phosphatase activity in purified Rtr1 and the absence of an active site in the structure of the yeast protein suggest that Rtr1 does not dephosphorylate RNA polymerase II. 10 Jul | Nat Commun 3:946 doi:10.1038/ncomms1947 (2012) Biological sciences Biochemistry  Molecular biology  Abstract | Full Text | PDF (525 kB) | Supplementary Information Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system OPEN Kirill A. Datsenko, Ksenia Pougach, Anton Tikhonov, Barry L. Wanner, Konstantin Severinov and Ekaterina Semenova The clustered regularly interspaced short palindromic repeats (CRISPR) system protects prokaryotes from foreign DNA. Here, bacteriophage DNA containing mutations that can circumvent this response are shown to be incorporated into the CRISPR locus, allowing bacteria to remember previous infections in an adaptive manner. 10 Jul | Nat Commun 3:945 doi:10.1038/ncomms1937 (2012) Biological sciences Biochemistry  Microbiology Molecular biology Abstract | Full Text | PDF (711 kB) | Supplementary Information Dynamics of multiple phases in a colossal-magnetoresistive manganite as revealed by dielectric spectroscopy Zhigao Sheng, Masao Nakamura, Fumitaka Kagawa, Masashi Kawasaki and Yoshinori Tokura Correlated electron oxide materials have rich phase diagrams with magnetic or electronic properties. Using a p-n junction configuration, Sheng et al. explore the dielectric response of different phases in manganite thin films and uncover their dynamic transport properties. 10 Jul | Nat Commun 3:944 doi:10.1038/ncomms1943 (2012) Physical sciences Applied physics  Condensed matter Materials science Abstract | Full Text | PDF (1,090 kB) | Supplementary Information Two-dome structure in electron-doped iron arsenide superconductors OPEN Soshi Iimura, Satoru Matuishi, Hikaru Sato, Taku Hanna, Yoshinori Muraba, Sung Wng Kim, Jung Eun Kim, Masaki Takata and Hideo Hosono The iron pnictides are a class of superconductors that have received widespread interest in recent years. By doping the prototypical material LaFeAsO with hydrogen, this study reveals the existence of a second superconducting dome at higher doping ranges, which arises due to orbital fluctuations. 10 Jul | Nat Commun 3:943 doi:10.1038/ncomms1913 (2012) Physical sciences Condensed matter  Materials science  Abstract | Full Text | PDF (1,114 kB) | Supplementary Information Photoinduced handedness switching in terahertz chiral metamolecules Shuang Zhang, Jiangfeng Zhou, Yong-Shik Park, Junsuk Rho, Ranjan Singh, Sunghyun Nam, Abul K. Azad, Hou-Tong Chen, Xiaobo Yin, Antoinette J. Taylor and Xiang Zhang Chiral metamaterials present interesting ways to manipulate and distinguish between different circular polarizations of light. Zhang et al. realize chiral metamaterials that exhibit photoinduced switching between left- and right-handed circular polarization interactions at terahertz frequencies. 10 Jul | Nat Commun 3:942 doi:10.1038/ncomms1908 (2012) Physical sciences  Materials science  Nanotechnology  Optical physics Abstract | Full Text | PDF (962 kB)   Nature Communications JOBS of the week Translational Cardiovascular Medicine Scientific teams and research staff Barts and the London School of Medicine and Dentistry 8 PhD Positions in Computational Biology European School of Molecular Medicine (SEMM) Immunologist Institute of Food Research Opportunities in Marine Geoscience National Oceanography Centre Postdoctoral Fellowship Lund University, Department of Laboratory Medicine Postdoctoral Position in Molecular Plasmonics Université de Bourgogne / University of Burgundy (France) Platform Support Officer - Colloidal Characterisation University of Melbourne, Australia Laboratory Manager / Research Assistant University of Texas Medical School at Houston Postdoctoral fellow Louisiana State University Health Science Center- New Orleans Bioinformatician / Web Developer European Bioinformatics Institute (EMBL-EBI) More Science jobs from Nature Communications EVENT 7th World Congress on Prevention of Diabetes and its Complications 12.-14.11.12 Madrid, Spain More science events from     Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. 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