Tuesday, July 3, 2012

Molecular Therapy - Table of Contents alert Volume 20 Issue 7


TABLE OF CONTENTS

Volume 20, Issue 7 (July 2012)

In this issue
Editorial
In This Issue
Research Highlights
Commentaries
Reviews
Original Articles

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Molecular Therapy-Nucleic Acids
Online. Open Access. High-Quality Research.

Molecular Therapy-Nucleic Acids is a peer-reviewed, fully open access, online journal. sibling journal to the well-established high impact journal, Molecular Therapy. The journal publishes high quality basic, translational, and clinical research and cutting edge reviews and commentaries targeted to the advances in oligonucleotide- and gene-based therapies.

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Editorial

Top

The ASGCT in 2012: Charting a Path to Bring Novel Biologic Therapies to the Clinic

Xandra O Breakefield

Mol Ther 2012 20: 1289-1290; 10.1038/mt.2012.122

Full Text

In This Issue

Top

In This Issue

Mol Ther 2012 20: 1292; 10.1038/mt.2012.123

Full Text

Research Highlights

Top

Research Highlights

Mol Ther 2012 20: 1293; 10.1038/mt.2012.124

Full Text

Commentaries

Top

Converting Scar to Muscle in the Injured Heart

Paul R Riley

Mol Ther 2012 20: 1294-1296; 10.1038/mt.2012.121

Full Text

Selectins for Cardiosphere Culture: The “E’s” Have It!

Darryl R Davis and Duncan J Stewart

Mol Ther 2012 20: 1296-1297; 10.1038/mt.2012.120

Full Text

Reviews

Top

In Vivo Gene Delivery by Nonviral Vectors: Overcoming Hurdles?

Yuan Zhang, Andrew Satterlee and Leaf Huang

Mol Ther 2012 20: 1298-1304; advance online publication, April 24, 2012; 10.1038/mt.2012.79

Abstract | Full Text

Original Articles

Top

Modulation of eIF5A Expression Using SNS01 Nanoparticles Inhibits NF-κB Activity and Tumor Growth in Murine Models of Multiple Myeloma

Catherine A Taylor, Zhongda Liu, Terence C Tang, Qifa Zheng, Sarah Francis, Tzann-Wei Wang, Bin Ye, John A Lust, Richard Dondero and John E Thompson

Mol Ther 2012 20: 1305-1314; advance online publication, May 15, 2012; 10.1038/mt.2012.94

Abstract | Full Text

Design of a Single AAV Vector for Coexpression of TH and GCH1 to Establish Continuous DOPA Synthesis in a Rat Model of Parkinson's Disease

Erik Cederfjäll, Gurdal Sahin, Deniz Kirik and Tomas Björklund

Mol Ther 2012 20: 1315-1326; advance online publication, January 31, 2012; 10.1038/mt.2012.1

Abstract | Full Text

Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease

Marina S Gorbatyuk, Arseniy Shabashvili, Weijun Chen, Craig Meyers, Layla F Sullivan, Max Salganik, Jonathan H Lin, Alfred S Lewin, Nicholas Muzyczka and Oleg S Gorbatyuk

Mol Ther 2012 20: 1327-1337; advance online publication, March 20, 2012; 10.1038/mt.2012.28

Abstract | Full Text

CNS-specific Therapy for Ongoing EAE by Silencing IL-17 Pathway in Astrocytes

Yaping Yan, Xiaoli Ding, Ke Li, Bogoljub Ciric, Shuai Wu, Hui Xu, Bruno Gran, Abdolmohamad Rostami and Guang-Xian Zhang

Mol Ther 2012 20: 1338-1348; advance online publication, March 20, 2012; 10.1038/mt.2012.12

Abstract | Full Text

Thymic Gene Transfer of Myelin Oligodendrocyte Glycoprotein Ameliorates the Onset but Not the Progression of Autoimmune Demyelination

Christopher Siatskas, Natalie Seach, Guizhi Sun, Ashley Emerson-Webber, Aude Silvain, Ban-Hock Toh, Frank Alderuccio, B Thomas Bäckström, Richard L Boyd and Claude C Bernard

Mol Ther 2012 20: 1349-1359; advance online publication, February 21, 2012; 10.1038/mt.2012.15

Abstract | Full Text

Human Erythropoietin Gene Delivery Using an Arginine-grafted Bioreducible Polymer System

Youngsook Lee, Hye Yeong Nam, Jaesung Kim, Minhyung Lee, James W Yockman, Sug Kyun Shin and Sung Wan Kim

Mol Ther 2012 20: 1360-1366; advance online publication, April 3, 2012; 10.1038/mt.2012.62

Abstract | Full Text

A Tubulin Binding Peptide Targets Glioma Cells Disrupting Their Microtubules, Blocking Migration, and Inducing Apoptosis

Raphael Berges, Julien Balzeau, Alan C Peterson and Joel Eyer

Mol Ther 2012 20: 1367-1377; advance online publication, April 10, 2012; 10.1038/mt.2012.45

Abstract | Full Text

Sustaining Cardiac Claudin-5 Levels Prevents Functional Hallmarks of Cardiomyopathy in a Muscular Dystrophy Mouse Model

Dawn A Delfín, Ying Xu, Kevin E Schill, Tessily A Mays, Benjamin D Canan, Kara E Zang, Jamie A Barnum, Paul ML Janssen and Jill A Rafael-Fortney

Mol Ther 2012 20: 1378-1383; advance online publication, May 1, 2012; 10.1038/mt.2012.81

Abstract | Full Text

Protein-anchoring Strategy for Delivering Acetylcholinesterase to the Neuromuscular Junction

Mikako Ito, Yumi Suzuki, Takashi Okada, Takayasu Fukudome, Toshiro Yoshimura, Akio Masuda, Shin'ichi Takeda, Eric Krejci and Kinji Ohno

Mol Ther 2012 20: 1384-1392; advance online publication, February 28, 2012; 10.1038/mt.2012.34

Abstract | Full Text

Sialic Acid Deposition Impairs the Utility of AAV9, but Not Peptide-modified AAVs for Brain Gene Therapy in a Mouse Model of Lysosomal Storage Disease

Yong Hong Chen, Kristin Claflin, James C Geoghegan and Beverly L Davidson

Mol Ther 2012 20: 1393-1399; advance online publication, May 15, 2012; 10.1038/mt.2012.100

Abstract | Full Text

The β-Globin Locus Control Region in Combination With the EF1α Short Promoter Allows Enhanced Lentiviral Vector-mediated Erythroid Gene Expression With Conserved Multilineage Activity

Claudia A Montiel-Equihua, Lin Zhang, Sean Knight, Heba Saadeh, Simone Scholz, Marlene Carmo, Maria E Alonso-Ferrero, Michael P Blundell, Aiste Monkeviciute, Reiner Schulz, Mary Collins, Yasuhiro Takeuchi, Manfred Schmidt, Lynette Fairbanks, Michael Antoniou, Adrian J Thrasher and H Bobby Gaspar

Mol Ther 2012 20: 1400-1409; advance online publication, March 20, 2012; 10.1038/mt.2012.50

Abstract | Full Text

Pharmacological Modulation of Humoral Immunity in a Nonhuman Primate Model of AAV Gene Transfer for Hemophilia B

Federico Mingozzi, Yifeng Chen, Samuel L Murphy, Shyrie C Edmonson, Alex Tai, Sandra D Price, Mark E Metzger, Shangzhen Zhou, J Fraser Wright, Robert E Donahue, Cynthia E Dunbar and Katherine A High

Mol Ther 2012 20: 1410-1416; advance online publication, May 8, 2012; 10.1038/mt.2012.84

Abstract | Full Text

RNA Interference Inhibits DUX4-induced Muscle Toxicity In Vivo: Implications for a Targeted FSHD Therapy

Lindsay M Wallace, Jian Liu, Jacqueline S Domire, Sara E Garwick-Coppens, Susan M Guckes, Jerry R Mendell, Kevin M Flanigan and Scott Q. Harper

Mol Ther 2012 20: 1417-1423; advance online publication, April 17, 2012; 10.1038/mt.2012.68

Abstract | Full Text

Spherical Bullet Formation via E-cadherin Promotes Therapeutic Potency of Mesenchymal Stem Cells Derived From Human Umbilical Cord Blood for Myocardial Infarction

Eun Ju Lee, Sung Jung Park, Soo Kyoung Kang, Gi-Hwan Kim, Hyun-Jae Kang, Sae-Won Lee, Hong Bae Jeon and Hyo-Soo Kim

Mol Ther 2012 20: 1424-1433; advance online publication, March 27, 2012; 10.1038/mt.2012.58

Abstract | Full Text

In Vivo Tracking of Mesechymal Stem Cells Using Fluorescent Nanoparticles in an Osteochondral Repair Model

Jong Min Lee, Byung-Soo Kim, Haeshin Lee and Gun-Il Im

Mol Ther 2012 20: 1434-1442; advance online publication, April 10, 2012; 10.1038/mt.2012.60

Abstract | Full Text

SCL/TAL1 Regulates Hematopoietic Specification From Human Embryonic Stem Cells

Pedro J Real, Gertrudis Ligero, Veronica Ayllon, Veronica Ramos-Mejia, Clara Bueno, Ivan Gutierrez-Aranda, Oscar Navarro-Montero, Majlinda Lako and Pablo Menendez

Mol Ther 2012 20: 1443-1453; advance online publication, April 10, 2012; 10.1038/mt.2012.49

Abstract | Full Text

Lentivector Transduction Improves Outcomes Over Transplantation of Human HSCs Alone in NOD/SCID/Fabry Mice

Natalia Pacienza, Makoto Yoshimitsu, Nobuo Mizue, Bryan CY Au, James CM Wang, Xin Fan, Toshihiro Takenaka and Jeffrey A Medin

Mol Ther 2012 20: 1454-1461; advance online publication, April 3, 2012; 10.1038/mt.2012.64

Abstract | Full Text

Off-the-shelf Adenoviral-mediated Immunotherapy via Bicistronic Expression of Tumor Antigen and iMyD88/CD40 Adjuvant

Jan Ole Kemnade, Mamatha Seethammagari, Priya Narayanan, Jonathan M Levitt, Alison A McCormick and David M Spencer

Mol Ther 2012 20: 1462-1471; advance online publication, March 20, 2012; 10.1038/mt.2012.48

Abstract | Full Text

DNA Vaccination in the Skin Using Microneedles Improves Protection Against Influenza

Jae-Min Song, Yeu-Chun Kim, Eunju O, Richard W Compans, Mark R Prausnitz and Sang-Moo Kang

Mol Ther 2012 20: 1472-1480; advance online publication, April 17, 2012; 10.1038/mt.2012.69

Abstract | Full Text

Molecular Therapy-Nucleic Acids
Online.Open Access.High-Quality Research.

Molecular Therapy-Nucleic Acidsis a peer-reviewed, fully open access, online journal. Sibling journal to the well-established high impact journal, Molecular Therapy. The journal publishes high quality basic, translational, and clinical research and cutting edge reviews and commentaries targeted to the advances in oligonucleotide- and gene-based therapies.
Submit your research TODAY!!
 

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