TABLE OF CONTENTS
|  |  |  | Volume 20, Issue 6 (June 2012) |  | In this issue Editorial In This Issue Research Highlights Meeting Report commentaries Reviews Original Articles Corrigendum
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| |  |  |  | | Advertisement |  | Molecular Therapy-Nucleic Acids Online. Open Access. High-Quality Research. Molecular Therapy-Nucleic Acids is a peer-reviewed, fully open access, online journal. sibling journal to the well-established high impact journal, Molecular Therapy. The journal publishes high quality basic, translational, and clinical research and cutting edge reviews and commentaries targeted to the advances in oligonucleotide- and gene-based therapies. Submit your research TODAY!! | |  | | | Editorial | Top |  | The Challenge of Using Gene- or Cell-Based Therapies to Treat Lung DiseaseRonald G Crystal Mol Ther 2012 20: 1077-1078; 10.1038/mt.2012.91 Full Text |  |  |  | It’s Time to End RAC Review of Gene Therapy ProtocolsGerard J McGarrity Mol Ther 2012 20: 1079-1080; 10.1038/mt.2012.92 Full Text |  | In This Issue | Top |  | In This IssueMol Ther 2012 20: 1082; 10.1038/mt.2012.105 Full Text |  | Research Highlights | Top |  | Research HighlightsMol Ther 2012 20: 1083; 10.1038/mt.2012.104 Full Text |  | Meeting Report | Top |  | Challenges in Vector and Trial Design Using Retroviral Vectors for Long-Term Gene Correction in Hematopoietic Stem Cell Gene TherapyJacqueline Corrigan-Curay, Odile Cohen-Haguenauer, Marina O’Reilly, Susan R. Ross, Hung Fan, Naomi Rosenberg, Nikunj Somia, Nancy King, Theodore Friedmann, Cynthia Dunbar, Alessandro Aiuti, Luigi Naldini, Christopher Baum, Christof von Kalle, Hans-Peter Kiem, Eugenio Montini, Frederic Bushman, Brian P Sorrentino, Manuel Carrondo, Harry Malech, Gösta Gahrton, Robyn Shapiro, Linda Wolff, Eugene Rosenthal, Robert Jambou, John Zaia and Donald B Kohn Mol Ther 2012 20: 1084-1094; 10.1038/mt.2012.93 Full Text |  | commentaries | Top |  | Novel Therapies, High-Risk Pediatric Research, and the Prospect of Benefit: Learning from the Ethical DisagreementsInmaculada de Melo-Martín, Dolan Sondhi and Ronald G Crystal Mol Ther 2012 20: 1095-1102; 10.1038/mt.2012.90 Full Text |  |  |  | Myocardial Repair and Regeneration: Bone Marrow or Cardiac Stem Cells?Keith G Oldroyd, Colin Berry and Jozef Bartunek Mol Ther 2012 20: 1102-1105; 10.1038/mt.2012.99 Full Text |  |  |  | Advances in Foamy Virus Vector Technology and Disease Correction Could Speed the Path to Clinical ApplicationEls Verhoeyen Mol Ther 2012 20: 1105-1107; 10.1038/mt.2012.97 Full Text |  | Reviews | Top |  | Advances in Cell and Gene-based Therapies for Cystic Fibrosis Lung DiseaseMayumi Oakland, Patrick L Sinn and Paul B McCray Jr Mol Ther 2012 20: 1108-1115; advance online publication, February 28, 2012; 10.1038/mt.2012.32 Abstract | Full Text |  |  |  | Stem Cells and Regenerative Medicine in Lung Biology and DiseasesAllison N Lau, Meagan Goodwin, Carla F Kim and Daniel J Weiss Mol Ther 2012 20: 1116-1130; advance online publication, March 6, 2012; 10.1038/mt.2012.37 Abstract | Full Text |  | Original Articles | Top |  | Long-term Correction of Very Long-chain Acyl-CoA Dehydrogenase Deficiency in Mice Using AAV9 Gene TherapyAllison M Keeler, Thomas Conlon, Glenn Walter, Huadong Zeng, Scott A Shaffer, Fu Dungtao, Kirsten Erger, Travis Cossette, Qiushi Tang, Christian Mueller and Terence R Flotte Mol Ther 2012 20: 1131-1138; advance online publication, March 6, 2012; 10.1038/mt.2012.39 Abstract | Full Text |  |  |  | Expression of Immunomodulatory Neutrophil-activating Protein of Helicobacter pylori Enhances the Antitumor Activity of Oncolytic Measles VirusIanko D Iankov, Cory Allen, Mark J Federspiel, Rae M Myers, Kah Whye Peng, James N Ingle, Stephen J Russell and Evanthia Galanis Mol Ther 2012 20: 1139-1147; advance online publication, February 14, 2012; 10.1038/mt.2012.4 Abstract | Full Text |  |  |  | ORFV: A Novel Oncolytic and Immune Stimulating Parapoxvirus TherapeuticJulia L Rintoul, Chantal G Lemay, Lee-Hwa Tai, Marianne M Stanford, Theresa J Falls, Christiano T de Souza, Byram W Bridle, Manijeh Daneshmand, Pamela S Ohashi, Yonghong Wan, Brian D Lichty, Andrew A Mercer, Rebecca C Auer, Harold L Atkins and John C Bell Mol Ther 2012 20: 1148-1157; advance online publication, January 24, 2012; 10.1038/mt.2011.301 Abstract | Full Text |  |  |  | Cell Membrane–associated Heparan Sulfate Is a Receptor for Prototype Foamy Virus in Human, Monkey, and Rodent CellsMd Nasimuzzaman and Derek A Persons Mol Ther 2012 20: 1158-1166; advance online publication, March 20, 2012; 10.1038/mt.2012.41 Abstract | Full Text |  |  |  | A Small-molecule-controlled System for Efficient Pseudotyping of Prototype Foamy Virus VectorsYu-Ping Ho, Viktor Schnabel, Anka Swiersy, Kristin Stirnnagel and Dirk Lindemann Mol Ther 2012 20: 1167-1176; advance online publication, April 3, 2012; 10.1038/mt.2012.61 Abstract | Full Text |  |  |  | Integration Frequency and Intermolecular Recombination of rAAV Vectors in Non-human Primate Skeletal Muscle and LiverAli Nowrouzi, Magalie Penaud-Budloo, Christine Kaeppel, Uwe Appelt, Caroline Le Guiner, Philippe Moullier, Christof von Kalle, Richard O Snyder and Manfred Schmidt Mol Ther 2012 20: 1177-1186; advance online publication, March 27, 2012; 10.1038/mt.2012.47 Abstract | Full Text |  |  |  | Lentiviral Vector Induced Insertional Haploinsufficiency of Ebf1 Causes Murine LeukemiaDirk Heckl, Adrian Schwarzer, Reinhard Haemmerle, Doris Steinemann, Cornelia Rudolph, Britta Skawran, Sabine Knoess, Johanna Krause, Zhixiong Li, Brigitte Schlegelberger, Christopher Baum and Ute Modlich Mol Ther 2012 20: 1187-1195; advance online publication, April 3, 2012; 10.1038/mt.2012.59 Abstract | Full Text |  |  |  | PEGylated Polyplex With Optimized PEG Shielding Enhances Gene Introduction in Lungs by Minimizing Inflammatory ResponsesSatoshi Uchida, Keiji Itaka, Qixian Chen, Kensuke Osada, Takehiko Ishii, Masa-Aki Shibata, Mariko Harada-Shiba and Kazunori Kataoka Mol Ther 2012 20: 1196-1203; advance online publication, February 14, 2012; 10.1038/mt.2012.20 Abstract | Full Text |  |  |  | Ex Vivo Adenoviral Vector Gene Delivery Results in Decreased Vector-associated Inflammation Pre- and Post–lung Transplantation in the PigJonathan C Yeung, Dirk Wagnetz, Marcelo Cypel, Matthew Rubacha, Terumoto Koike, Yi-Min Chun, Jim Hu, Thomas K Waddell, David M Hwang, Mingyao Liu and Shaf Keshavjee Mol Ther 2012 20: 1204-1211; advance online publication, March 27, 2012; 10.1038/mt.2012.57 Abstract | Full Text |  |  |  | Engineering Multiple U7snRNA Constructs to Induce Single and Multiexon-skipping for Duchenne Muscular DystrophyAurélie Goyenvalle, Jordan Wright, Arran Babbs, Vivienne Wilkins, Luis Garcia and Kay E Davies Mol Ther 2012 20: 1212-1221; advance online publication, February 21, 2012; 10.1038/mt.2012.26 Abstract | Full Text |  |  |  | Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle PathogenesisLijun Wang, Liang Zhou, Peiyong Jiang, Leina Lu, Xiaona Chen, Huiyao Lan, Denis C Guttridge, Hao Sun and Huating Wang Mol Ther 2012 20: 1222-1233; advance online publication, March 20, 2012; 10.1038/mt.2012.35 Abstract | Full Text |  |  |  | A New Therapeutic Approach Using a Schizophyllan-based Drug Delivery System for Inflammatory Bowel DiseaseHidetoshi Takedatsu, Keiichi Mitsuyama, Shinichi Mochizuki, Teppei Kobayashi, Kazuo Sakurai, Hiroshi Takeda, Yoshihide Fujiyama, Yoshikazu Koyama, Jun Nishihira and Michio Sata Mol Ther 2012 20: 1234-1241; advance online publication, February 14, 2012; 10.1038/mt.2012.24 Abstract | Full Text |  |  |  | Isolation and Optimization of Murine IL-10 Receptor Blocking Oligonucleotide Aptamers Using High-throughput SequencingAlexey Berezhnoy, C. Andrew Stewart, James O. Mcnamara II, William Thiel, Paloma Giangrande, Giorgio Trinchieri and Eli Gilboa Mol Ther 2012 20: 1242-1250; advance online publication, March 20, 2012; 10.1038/mt.2012.18 Abstract | Full Text |  |  |  | miR-29 Inhibits Bleomycin-induced Pulmonary Fibrosis in MiceJun Xiao, Xiao-Ming Meng, Xiao R Huang, Arthur CK Chung, Yu-Lin Feng, David SC Hui, Cheuk-Man Yu, Joseph JY Sung and Hui Y Lan Mol Ther 2012 20: 1251-1260; advance online publication, March 6, 2012; 10.1038/mt.2012.36 Abstract | Full Text |  |  |  | Lipid-based Nanoparticle Delivery of Pre-miR-107 Inhibits the Tumorigenicity of Head and Neck Squamous Cell CarcinomaLongzhu Piao, Manchao Zhang, Jharna Datta, Xiujie Xie, Tizhi Su, Hong Li, Theodoros N Teknos and Quintin Pan Mol Ther 2012 20: 1261-1269; advance online publication, April 10, 2012; 10.1038/mt.2012.67 Abstract | Full Text |  |  |  | Foamy Virus Vector-mediated Gene Correction of a Mouse Model of Wiskott–Aldrich SyndromeToru Uchiyama, Marsilio Adriani, G Jayashree Jagadeesh, Adam Paine and Fabio Candotti Mol Ther 2012 20: 1270-1279; advance online publication, January 3, 2012; 10.1038/mt.2011.282 Abstract | Full Text |  |  |  | Cellular Therapy With Ixmyelocel-T to Treat Critical Limb Ischemia: The Randomized, Double-blind, Placebo-controlled RESTORE-CLI TrialRichard J Powell, William A Marston, Scott A Berceli, Raul Guzman, Timothy D Henry, Amy T Longcore, Theresa P Stern, Sharon Watling and Ronnda L Bartel Mol Ther 2012 20: 1280-1286; advance online publication, March 27, 2012; 10.1038/mt.2012.52 Abstract | Full Text |  | Corrigendum | Top |  | Long-term Correction of Very Long-chain Acyl-CoA Dehydrogenase Deficiency in Mice Using AAV9 Gene TherapyMol Ther 2012 20: 1287; 10.1038/mt.2012.106 Full Text |  |  |  |  |  | Pediatric Research Reviews Highlights Cell-based therapies in 2012 Published in April 2012 as a special supplemental issue of Pediatric Research, the annual review issue highlights cell-based therapies in pediatrics. The articles in this issue examine developments in cell-based therapies used for treating neonatal/pediatric neuronal damage, hematologic diseases, chronic inflammatory diseases and cancers. Visit www.nature.com/pr and gain access to these articles before they are published in print. | |  | | | Please note that you need to be a subscriber or site-license holder to enjoy full-text access to Molecular Therapy. In order to do so, please purchase a subscription. You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department. For print subscription enquiries, please contact our subscription department. 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