Friday, June 1, 2012

Molecular Therapy - Table of Contents alert Volume 20 Issue 6


TABLE OF CONTENTS

Volume 20, Issue 6 (June 2012)

In this issue
Editorial
In This Issue
Research Highlights
Meeting Report
commentaries
Reviews
Original Articles
Corrigendum

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Molecular Therapy-Nucleic Acids
Online. Open Access. High-Quality Research.

Molecular Therapy-Nucleic Acids is a peer-reviewed, fully open access, online journal. sibling journal to the well-established high impact journal, Molecular Therapy. The journal publishes high quality basic, translational, and clinical research and cutting edge reviews and commentaries targeted to the advances in oligonucleotide- and gene-based therapies.

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Editorial

Top

The Challenge of Using Gene- or Cell-Based Therapies to Treat Lung Disease

Ronald G Crystal

Mol Ther 2012 20: 1077-1078; 10.1038/mt.2012.91

Full Text

It’s Time to End RAC Review of Gene Therapy Protocols

Gerard J McGarrity

Mol Ther 2012 20: 1079-1080; 10.1038/mt.2012.92

Full Text

In This Issue

Top

In This Issue

Mol Ther 2012 20: 1082; 10.1038/mt.2012.105

Full Text

Research Highlights

Top

Research Highlights

Mol Ther 2012 20: 1083; 10.1038/mt.2012.104

Full Text

Meeting Report

Top

Challenges in Vector and Trial Design Using Retroviral Vectors for Long-Term Gene Correction in Hematopoietic Stem Cell Gene Therapy

Jacqueline Corrigan-Curay, Odile Cohen-Haguenauer, Marina O’Reilly, Susan R. Ross, Hung Fan, Naomi Rosenberg, Nikunj Somia, Nancy King, Theodore Friedmann, Cynthia Dunbar, Alessandro Aiuti, Luigi Naldini, Christopher Baum, Christof von Kalle, Hans-Peter Kiem, Eugenio Montini, Frederic Bushman, Brian P Sorrentino, Manuel Carrondo, Harry Malech, Gösta Gahrton, Robyn Shapiro, Linda Wolff, Eugene Rosenthal, Robert Jambou, John Zaia and Donald B Kohn

Mol Ther 2012 20: 1084-1094; 10.1038/mt.2012.93

Full Text

commentaries

Top

Novel Therapies, High-Risk Pediatric Research, and the Prospect of Benefit: Learning from the Ethical Disagreements

Inmaculada de Melo-Martín, Dolan Sondhi and Ronald G Crystal

Mol Ther 2012 20: 1095-1102; 10.1038/mt.2012.90

Full Text

Myocardial Repair and Regeneration: Bone Marrow or Cardiac Stem Cells?

Keith G Oldroyd, Colin Berry and Jozef Bartunek

Mol Ther 2012 20: 1102-1105; 10.1038/mt.2012.99

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Advances in Foamy Virus Vector Technology and Disease Correction Could Speed the Path to Clinical Application

Els Verhoeyen

Mol Ther 2012 20: 1105-1107; 10.1038/mt.2012.97

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Reviews

Top

Advances in Cell and Gene-based Therapies for Cystic Fibrosis Lung Disease

Mayumi Oakland, Patrick L Sinn and Paul B McCray Jr

Mol Ther 2012 20: 1108-1115; advance online publication, February 28, 2012; 10.1038/mt.2012.32

Abstract | Full Text

Stem Cells and Regenerative Medicine in Lung Biology and Diseases

Allison N Lau, Meagan Goodwin, Carla F Kim and Daniel J Weiss

Mol Ther 2012 20: 1116-1130; advance online publication, March 6, 2012; 10.1038/mt.2012.37

Abstract | Full Text

Original Articles

Top

Long-term Correction of Very Long-chain Acyl-CoA Dehydrogenase Deficiency in Mice Using AAV9 Gene Therapy

Allison M Keeler, Thomas Conlon, Glenn Walter, Huadong Zeng, Scott A Shaffer, Fu Dungtao, Kirsten Erger, Travis Cossette, Qiushi Tang, Christian Mueller and Terence R Flotte

Mol Ther 2012 20: 1131-1138; advance online publication, March 6, 2012; 10.1038/mt.2012.39

Abstract | Full Text

Expression of Immunomodulatory Neutrophil-activating Protein of Helicobacter pylori Enhances the Antitumor Activity of Oncolytic Measles Virus

Ianko D Iankov, Cory Allen, Mark J Federspiel, Rae M Myers, Kah Whye Peng, James N Ingle, Stephen J Russell and Evanthia Galanis

Mol Ther 2012 20: 1139-1147; advance online publication, February 14, 2012; 10.1038/mt.2012.4

Abstract | Full Text

ORFV: A Novel Oncolytic and Immune Stimulating Parapoxvirus Therapeutic

Julia L Rintoul, Chantal G Lemay, Lee-Hwa Tai, Marianne M Stanford, Theresa J Falls, Christiano T de Souza, Byram W Bridle, Manijeh Daneshmand, Pamela S Ohashi, Yonghong Wan, Brian D Lichty, Andrew A Mercer, Rebecca C Auer, Harold L Atkins and John C Bell

Mol Ther 2012 20: 1148-1157; advance online publication, January 24, 2012; 10.1038/mt.2011.301

Abstract | Full Text

Cell Membrane–associated Heparan Sulfate Is a Receptor for Prototype Foamy Virus in Human, Monkey, and Rodent Cells

Md Nasimuzzaman and Derek A Persons

Mol Ther 2012 20: 1158-1166; advance online publication, March 20, 2012; 10.1038/mt.2012.41

Abstract | Full Text

A Small-molecule-controlled System for Efficient Pseudotyping of Prototype Foamy Virus Vectors

Yu-Ping Ho, Viktor Schnabel, Anka Swiersy, Kristin Stirnnagel and Dirk Lindemann

Mol Ther 2012 20: 1167-1176; advance online publication, April 3, 2012; 10.1038/mt.2012.61

Abstract | Full Text

Integration Frequency and Intermolecular Recombination of rAAV Vectors in Non-human Primate Skeletal Muscle and Liver

Ali Nowrouzi, Magalie Penaud-Budloo, Christine Kaeppel, Uwe Appelt, Caroline Le Guiner, Philippe Moullier, Christof von Kalle, Richard O Snyder and Manfred Schmidt

Mol Ther 2012 20: 1177-1186; advance online publication, March 27, 2012; 10.1038/mt.2012.47

Abstract | Full Text

Lentiviral Vector Induced Insertional Haploinsufficiency of Ebf1 Causes Murine Leukemia

Dirk Heckl, Adrian Schwarzer, Reinhard Haemmerle, Doris Steinemann, Cornelia Rudolph, Britta Skawran, Sabine Knoess, Johanna Krause, Zhixiong Li, Brigitte Schlegelberger, Christopher Baum and Ute Modlich

Mol Ther 2012 20: 1187-1195; advance online publication, April 3, 2012; 10.1038/mt.2012.59

Abstract | Full Text

PEGylated Polyplex With Optimized PEG Shielding Enhances Gene Introduction in Lungs by Minimizing Inflammatory Responses

Satoshi Uchida, Keiji Itaka, Qixian Chen, Kensuke Osada, Takehiko Ishii, Masa-Aki Shibata, Mariko Harada-Shiba and Kazunori Kataoka

Mol Ther 2012 20: 1196-1203; advance online publication, February 14, 2012; 10.1038/mt.2012.20

Abstract | Full Text

Ex Vivo Adenoviral Vector Gene Delivery Results in Decreased Vector-associated Inflammation Pre- and Post–lung Transplantation in the Pig

Jonathan C Yeung, Dirk Wagnetz, Marcelo Cypel, Matthew Rubacha, Terumoto Koike, Yi-Min Chun, Jim Hu, Thomas K Waddell, David M Hwang, Mingyao Liu and Shaf Keshavjee

Mol Ther 2012 20: 1204-1211; advance online publication, March 27, 2012; 10.1038/mt.2012.57

Abstract | Full Text

Engineering Multiple U7snRNA Constructs to Induce Single and Multiexon-skipping for Duchenne Muscular Dystrophy

Aurélie Goyenvalle, Jordan Wright, Arran Babbs, Vivienne Wilkins, Luis Garcia and Kay E Davies

Mol Ther 2012 20: 1212-1221; advance online publication, February 21, 2012; 10.1038/mt.2012.26

Abstract | Full Text

Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle Pathogenesis

Lijun Wang, Liang Zhou, Peiyong Jiang, Leina Lu, Xiaona Chen, Huiyao Lan, Denis C Guttridge, Hao Sun and Huating Wang

Mol Ther 2012 20: 1222-1233; advance online publication, March 20, 2012; 10.1038/mt.2012.35

Abstract | Full Text

A New Therapeutic Approach Using a Schizophyllan-based Drug Delivery System for Inflammatory Bowel Disease

Hidetoshi Takedatsu, Keiichi Mitsuyama, Shinichi Mochizuki, Teppei Kobayashi, Kazuo Sakurai, Hiroshi Takeda, Yoshihide Fujiyama, Yoshikazu Koyama, Jun Nishihira and Michio Sata

Mol Ther 2012 20: 1234-1241; advance online publication, February 14, 2012; 10.1038/mt.2012.24

Abstract | Full Text

Isolation and Optimization of Murine IL-10 Receptor Blocking Oligonucleotide Aptamers Using High-throughput Sequencing

Alexey Berezhnoy, C. Andrew Stewart, James O. Mcnamara II, William Thiel, Paloma Giangrande, Giorgio Trinchieri and Eli Gilboa

Mol Ther 2012 20: 1242-1250; advance online publication, March 20, 2012; 10.1038/mt.2012.18

Abstract | Full Text

miR-29 Inhibits Bleomycin-induced Pulmonary Fibrosis in Mice

Jun Xiao, Xiao-Ming Meng, Xiao R Huang, Arthur CK Chung, Yu-Lin Feng, David SC Hui, Cheuk-Man Yu, Joseph JY Sung and Hui Y Lan

Mol Ther 2012 20: 1251-1260; advance online publication, March 6, 2012; 10.1038/mt.2012.36

Abstract | Full Text

Lipid-based Nanoparticle Delivery of Pre-miR-107 Inhibits the Tumorigenicity of Head and Neck Squamous Cell Carcinoma

Longzhu Piao, Manchao Zhang, Jharna Datta, Xiujie Xie, Tizhi Su, Hong Li, Theodoros N Teknos and Quintin Pan

Mol Ther 2012 20: 1261-1269; advance online publication, April 10, 2012; 10.1038/mt.2012.67

Abstract | Full Text

Foamy Virus Vector-mediated Gene Correction of a Mouse Model of Wiskott–Aldrich Syndrome

Toru Uchiyama, Marsilio Adriani, G Jayashree Jagadeesh, Adam Paine and Fabio Candotti

Mol Ther 2012 20: 1270-1279; advance online publication, January 3, 2012; 10.1038/mt.2011.282

Abstract | Full Text

Cellular Therapy With Ixmyelocel-T to Treat Critical Limb Ischemia: The Randomized, Double-blind, Placebo-controlled RESTORE-CLI Trial

Richard J Powell, William A Marston, Scott A Berceli, Raul Guzman, Timothy D Henry, Amy T Longcore, Theresa P Stern, Sharon Watling and Ronnda L Bartel

Mol Ther 2012 20: 1280-1286; advance online publication, March 27, 2012; 10.1038/mt.2012.52

Abstract | Full Text

Corrigendum

Top

Long-term Correction of Very Long-chain Acyl-CoA Dehydrogenase Deficiency in Mice Using AAV9 Gene Therapy

Mol Ther 2012 20: 1287; 10.1038/mt.2012.106

Full Text

Pediatric Research Reviews
Highlights Cell-based therapies in 2012

Published in April 2012 as a special supplemental issue of Pediatric Research, the annual review issue highlights cell-based therapies in pediatrics. The articles in this issue examine developments in cell-based therapies used for treating neonatal/pediatric neuronal damage, hematologic diseases, chronic inflammatory diseases and cancers.

Visit www.nature.com/pr and gain access to these articles before they are published in print.
 

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