chemistry@nature contents: 25 June 2012

Bringing you the latest and best in chemistry news and research from Nature Publishing Group For more information, see each journal's latest table of contents: Nature Nature Biotechnology Nature Chemical Biology Nature Chemistry Nature Materials Nature Methods Nature Nanotechnology Nature Protocols Nature Reviews Drug Discovery 25 June 2012 Primary Research Protocols Review Articles Blog Entries from The Sceptical Chymist Advertisement The Arab world has a rich history of scientific breakthroughs. Ensure you're part of the scientific and medical community gaining access to a regularly updated list of science jobs and local events in the Middle East. www.nature.com/nmiddleeast/ Follow us: Facebook, Twitter, & Google +   Primary Research top  Chemistry@nature JOBS of the week PhD fellowship Surface Chemistry Max Planck Institute for Chemical Ecology M.Sc. / Ph.D. Opportunities in Hydrothermal Chemistry University of Guelph Research Associate with Experience in Analytical Chemistry (m / f) Laimburg Research Centre for Agriculture and Forestry PhD Studentships in Organic Chemistry The University of Namur Research fellow in the Laboratories of AQUATIC TOXICOLOGY AND ICHTYOPATHOLOGY and ENVIRONMENTAL CHEMISTRY AND BIOCHEMISTRY University of South Bohemia in Ceské Budejovice, Faculty of Fisheries and Protection of Waters More Science jobs from Chemistry@nature EVENT 40th International Conference on Coordination Chemistry 09.-13.09.12 Valencia, Spain More science events from Chemical genetic discovery of targets and anti-targets for cancer polypharmacology Arvin C. Dar et al. Nature doi:10.1038/nature11127 Abstract Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch Aiming Ren et al. Nature doi:10.1038/nature11152 Abstract Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis Micheline N. Ngaki et al. Nature doi:10.1038/nature11009 Abstract Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing Timothy A Whitehead et al. Nature Biotechnology doi:10.1038/nbt.2214 Abstract KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry Karin Betz et al. Nature Chemical Biology doi:10.1038/nchembio.966 Abstract Divergence of multimodular polyketide synthases revealed by a didomain structure Jianting Zheng et al. Nature Chemical Biology doi:10.1038/nchembio.964 Abstract Deciphering biased-agonism complexity reveals a new active AT1 receptor entity Aude Sauliere et al. Nature Chemical Biology doi:10.1038/nchembio.961 Abstract A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer Stefanie Blattermann et al. Nature Chemical Biology doi:10.1038/nchembio.962 Abstract Direct and selective small-molecule activation of proapoptotic BAX Evripidis Gavathiotis et al. Nature Chemical Biology doi:10.1038/nchembio.995 Abstract ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53 Kelly D Sullivan et al. Nature Chemical Biology doi:10.1038/nchembio.965 Abstract Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization Karen Stanger et al. Nature Chemical Biology doi:10.1038/nchembio.967 Abstract Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome Cory D Rillahan et al. Nature Chemical Biology doi:10.1038/nchembio.999 Abstract Lys34 of translation elongation factor EF-P is hydroxylated by YfcM Lauri Peil et al. Nature Chemical Biology doi:10.1038/nchembio.1001 Abstract Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria Lihi Adler-Abramovich et al. Nature Chemical Biology doi:10.1038/nchembio.1002 Abstract Mechanically induced chemiluminescence from polymers incorporating a 1,2-dioxetane unit in the main chain Yulan Chen et al. Nature Chemistry doi:10.1038/nchem.1358 Abstract Single solvent molecules can affect the dynamics of substitution reactions R. Otto, J. Brox, S. Trippel, M. Stei, T. Best & R. Wester Nature Chemistry doi:10.1038/nchem.1362 Abstract An ultrasensitive universal detector based on neutralizer displacement Jagotamoy Das et al. Nature Chemistry doi:10.1038/nchem.1367 Abstract Closed-shell and open-shell square-planar iridium nitrido complexes Markus G. Scheibel et al. Nature Chemistry doi:10.1038/nchem.1368 Abstract Controlled homocatenation of boron on a transition metal Holger Braunschweig et al. Nature Chemistry doi:10.1038/nchem.1379 Abstract Crystal structure of δ-[Ru(bpy)2dppz]2+ bound to mismatched DNA reveals side-by-side metalloinsertion and intercalation Hang Song, Jens T. Kaiser & Jacqueline K. Barton Nature Chemistry doi:10.1038/nchem.1375 Abstract An improved high-performance lithium-air battery Hun-Gi Jung et al. Nature Chemistry doi:10.1038/nchem.1376 Abstract Non-Markovian polymer reaction kinetics T. Guerin, O. Benichou & R. Voituriez Nature Chemistry doi:10.1038/nchem.1378 Abstract The synthesis, crystal structure and charge-transport properties of hexacene Motonori Watanabe et al. Nature Chemistry doi:10.1038/nchem.1381 Abstract Enantioselective synthesis of a chiral nitrogen-doped buckybowl Qitao Tan, Shuhei Higashibayashi, Sangita Karanjit & Hidehiro Sakurai Nature Communications doi:10.1038/ncomms1896 Abstract Transmembrane anion transport mediated by halogen-bond donors Andreas Vargas Jentzsch et al. Nature Communications doi:10.1038/ncomms1902 Abstract A partially interpenetrated metal-organic framework for selective hysteretic sorption of carbon dioxide Sihai Yang et al. Nature Materials doi:10.1038/nmat3343 Abstract Plasmonic nanosensors with inverse sensitivity by means of enzyme-guided crystal growth Laura Rodriguez-Lorenzo et al. Nature Materials doi:10.1038/nmat3337 Abstract In silico screening of carbon-capture materials Li-Chiang Lin et al. Nature Materials doi:10.1038/nmat3336 Abstract Al13Fe4 as a low-cost alternative for palladium in heterogeneous hydrogenation M. Armbruster et al. Nature Materials doi:10.1038/nmat3347 Abstract Extraordinarily complex crystal structure with mesoscopic patterning in barium at high pressure I. Loa, R. J. Nelmes, L. F. Lundegaard & M. I. McMahon Nature Materials doi:10.1038/nmat3342 Abstract Single-cell systems biology by super-resolution imaging and combinatorial labeling Eric Lubeck & Long Cai Nature Methods doi:10.1038/nmeth.2069 Abstract Protein-inorganic hybrid nanoflowers Ge, J., Lei, J. & Zare, R. N. Nature Nanotechnology doi:10.1038/nnano.2012.80 Abstract Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery Lee, H. et al. Nature Nanotechnology doi:10.1038/nnano.2012.73 Abstract An oxygen reduction electrocatalyst based on carbon nanotube-graphene complexes Li, Y. et al. Nature Nanotechnology doi:10.1038/nnano.2012.72 Abstract Self-orienting nanocubes for the assembly of plasmonic nanojunctions Gao, B., Arya, G. & Tao, A. R. Nature Nanotechnology doi:10.1038/nnano.2012.83 Abstract   Protocols top  Synthesis of oligo(poly(ethylene glycol) fumarate) Lucas A Kinard, F Kurtis Kasper & Antonios G Mikos Nature Protocols doi:10.1038/nprot.2012.055 Abstract Synthesis of polystyrene microspheres and functionalization with Pd0 nanoparticles to perform bioorthogonal organometallic chemistry in living cells Asier Unciti-Broceta et al. Nature Protocols doi:10.1038/nprot.2012.052 Abstract Microwave-assisted preparation of the quorum-sensing molecule 2-heptyl-3-hydroxy-4(1H)-quinolone and structurally related analogs James T Hodgkinson, Warren R J D Galloway, Martin Welch & David R Spring Nature Protocols doi:10.1038/nprot.2012.054 Abstract Copper(I)/TEMPO-catalyzed aerobic oxidation of primary alcohols to aldehydes with ambient air Jessica M Hoover, Janelle E Steves & Shannon S Stahl Nature Protocols doi:10.1038/nprot.2012.057 Abstract Convergent synthesis of aminomethylene peptidomimetics Naila Assem & Andrei K Yudin Nature Protocols doi:10.1038/nprot.2012.066 Abstract   Review Articles top  The gold-sulfur interface at the nanoscale Hannu Hakkinen Nature Chemistry doi:10.1038/nchem.1352 Abstract   Blog Entries from The Sceptical Chymist top  Reactions: Stephane Roche Stephane Roche is in the Department of Chemistry and Biochemistry at Florida Atlantic University, and works on chemical synthesis, peptide assembly and total synthesis of bioactive natural products. Read Now Blogroll: Space dinosaurs! Highly respected organic chemist publishes a Perspective in JACS, chaos ensues. Read Now Reactions: Tiberiu Moga Tiberiu Moga is an undergraduate student in Medical Education at the University of Toronto Faculty of Medicine, studying to complete a medical degree - and is also one of the winners of our In Your Element essay competition (we’ll be featuring the winners on Reactions over the coming months). Read Now A new focal point for industry-academia networking Anyone who is watching the slow-motion train wreck that is the Eurozone can see that we are in trouble. 'National emergency'-type trouble... Read Now Goodbye and thanks As Stu announced about 3 months ago, I'm leaving Nature Chemistry today! It's been a real privilege to be involved right from the start... Read Now Reactions: Paul Clarke Paul Clarke is in the Department of Chemistry at The University of York, and works on the total synthesis of natural products and the prebiotic genesis of carbohydrates. Read Now Ambiguous bromine At first sight bromine seems to be 'just another halogen', a helpful counter-anion or leaving group in SN2 or cross-coupling reactions. Of course this isn’t the whole story, as Matt Rattley - a chemistry student at the University of Oxford and the author of the winning essay on bromine for last year's contest - points out in his article.... Read Now Reactions: Katharina Fromm Katharina M. Fromm is in the Department of Chemistry at the University of Fribourg, Switzerland, and works on coordination chemistry, in particular on mixed metal precursors for oxidic materials as well as coordination polymers with applications in materials science as well as medicine. Read Now Advertisement The June special issue of Polymer Journal on Self-Assembled Materials covers a variety of materials, including polymers, polymer/inorganic hybrids, assemblies of low molecular weight compounds, and nanoparticles. Access the Self-Assembled Materials special issue today! You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/nams/svc/myaccount (You will need to log in to be recognised as a nature.com registrant). 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