News: Carbon's neighbour By Patrick Mahony  | | Another use of boron is in borosilicate glass, often used in laboratory glassware. | Carbon is often called the 'element of life'. It can be found in proteins that make up living cells and in sugars and fats that power them. Carbon combines with hydrogen, as well as other elements, to form millions of different compounds with different uses. What about carbon's neighbour? Boron sits next-door, just left of carbon on the periodic table. Given their close proximity, how come carbon seems so important, yet many haven't even heard of boron? Carbon and boron are similar, but not the same. A key difference is that carbon has four 'spare' electrons easily used to form chemical bonds, while boron only has three. Carbon can form many stable compounds, while boron's 'electron deficiency' means many of its compounds react very easily. One of the simplest boron compounds, diborane, is so unstable it spontaneously combusts in air. Boron has potential medical applications. While simple boron and hydrogen compounds are highly unstable, boron is able to form large molecules called clusters that contain many boron atoms. These clusters form highly stable structures that can act as 'cages' for other molecules. Most pharmaceuticals are based on carbon. One problem for these drugs is selectivity making sure they only affect the target and not healthy cells. In many cases, this isn't a problem, but with diseases such as cancer, doctors only want to kill tumour cells. Many carbon-based drugs aren't very selective. Chemists hope to use boron-based drugs that are more selective to treat a range of diseases, including various cancers, Alzheimer's disease and depression. The boron-based drugs could be used directly, or as a 'cage' to protect and transport another drug. While it might not be as common or as popular as its famous neighbour, it appears there is a place for boron in our medical future. More information Careers link |
No comments:
Post a Comment