SPECIAL FEATURE: The role of type I interferons in regulating innate and adaptive immune responses |
|  | The innate immune response recognises pathogens and sterile danger signals to generate effector cytokines, such as type I interferons (IFNs), with a high degree of sophistication. The May/June 2012 issue provides a series of reviews of the role of type I IFNs in regulating immune responses. Topics to be covered include the reason for the induction of IFNs, type I IFNs interactions with and regulation of target cells (e.g. T cells, B cells and Th10 cells) in the immune system, and the roles and mechanisms of IFNs in specific organs or diseases. The accompanying web focus presents links to related articles from across Nature Publishing Group to provide more background information about these proteins. |  | TABLE OF CONTENTS
|  |  |  | Volume 90, Issue 5 (May/June 2012) |  | In this issue News And Commentary Editorial Reviews Original Articles Short Communication Corrigendum
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| |  |  |  | | Advertisement |  | Immunology and Cell Biology is proud to present a Special Feature and web focus on the role of type I IFNs in regulating immune responses, which include the reasons for the presence of IFNs, type I IFNs interactions with target cells in the immune system, and the roles and mechanisms of IFNs in specific organs or diseases. Access the Web Focus today! | |  | | | News And Commentary | Top |  | Stromal cells put the brakes on T-cell responsesTroy D Randall Immunol Cell Biol 2012 90: 469-470; advance online publication, November 29, 2011; 10.1038/icb.2011.106 Full Text |  | Editorial | Top |  | Overview. Type I interferons as primers, activators and inhibitors of innate and adaptive immune responsesPaul J Hertzog Immunol Cell Biol 2012 90: 471-473; 10.1038/icb.2012.15 Full Text | PDF |  | Reviews | Top |  | Induction of type I IFNs by intracellular DNA-sensing pathwaysTaner Cavlar, Andrea Ablasser and Veit Hornung Immunol Cell Biol 2012 90: 474-482; advance online publication, March 27, 2012; 10.1038/icb.2012.11 Abstract | Full Text |  |  |  | The interferons and their receptors—distribution and regulationNicole A de Weerd and Thao Nguyen Immunol Cell Biol 2012 90: 483-491; advance online publication, March 13, 2012; 10.1038/icb.2012.9 Abstract | Full Text |  |  |  | Modulation of T-cell function by type I interferonDavid F Tough Immunol Cell Biol 2012 90: 492-497; advance online publication, March 6, 2012; 10.1038/icb.2012.7 Abstract | Full Text |  |  |  | Role of type I interferons in the activation of autoreactive B cellsKerstin Kiefer, Michael A Oropallo, Michael P Cancro and Ann Marshak-Rothstein Immunol Cell Biol 2012 90: 498-504; advance online publication, March 20, 2012; 10.1038/icb.2012.10 Abstract | Full Text |  |  |  | Endogenous, or therapeutically induced, type I interferon responses differentially modulate Th1/Th17-mediated autoimmunity in the CNSUlrich Kalinke and Marco Prinz Immunol Cell Biol 2012 90: 505-509; advance online publication, March 20, 2012; 10.1038/icb.2012.8 Abstract | Full Text |  |  |  | Type I interferons in regulation of mucosal immunityNiamh E Mangan and Ka Yee Fung Immunol Cell Biol 2012 90: 510-519; advance online publication, March 20, 2012; 10.1038/icb.2012.13 Abstract | Full Text |  |  |  | Interferon signatures in immune disorders and diseaseSamuel Forster Immunol Cell Biol 2012 90: 520-527; advance online publication, April 10, 2012; 10.1038/icb.2012.12 Abstract | Full Text |  | Original Articles | Top |  | Immunoglobulin light chain, Blimp-1 and cytochrome P4501B1 peptides as potential vaccines for AL amyloidosisAmanda Flies, Tahamtan Ahmadi, Ashley J Parks, Tatiana Prokaeva, Liangping Weng, Sandra Solomon Rolfe, David C Seldin and David H Sherr Immunol Cell Biol 2012 90: 528-539; advance online publication, September 6, 2011; 10.1038/icb.2011.73 Abstract | Full Text |  |  |  | ISCOMATRIX vaccines mediate CD8+ T-cell cross-priming by a MyD88-dependent signaling pathwayNicholas S Wilson, Becky Yang, Adriana Baz Morelli, Sandra Koernig, Annie Yang, Stefanie Loeser, Denise Airey, Larissa Provan, Phil Hass, Hal Braley, Suzana Couto, Debbie Drane, Jeff Boyle, Gabrielle T Belz, Avi Ashkenazi and Eugene Maraskovsky Immunol Cell Biol 2012 90: 540-552; advance online publication, September 6, 2011; 10.1038/icb.2011.71 Abstract | Full Text |  |  |  | Protection against Nippostrongylus brasiliensis infection in mice is independent of GM-CSFDoris S C Shim, Heidi C Schilter, Michelle L Knott, Ranni A Almeida, Robert P Short, Charles R Mackay, Lindsay A Dent and William A Sewell Immunol Cell Biol 2012 90: 553-558; advance online publication, August 16, 2011; 10.1038/icb.2011.69 Abstract | Full Text |  | Short Communication | Top |  | LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signalingClaire J Greenhill, Jodee Gould, Matthias Ernst, Andrew Jarnicki, Paul J Hertzog, Ashley Mansell and Brendan J Jenkins Immunol Cell Biol 2012 90: 559-563; advance online publication, June 14, 2011; 10.1038/icb.2011.56 Abstract | Full Text |  | Corrigendum | Top |  | LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signalingClaire J Greenhill, Jodee Gould, Matthias Ernst, Andrew Jarnicki, Paul J Hertzog, Ashley Mansell and Brendan J Jenkins Immunol Cell Biol 2012 90: 564; 10.1038/icb.2012.25 Full Text |  |  |  |  |  | | Advertisement |  | |
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