Molecular Therapy - Table of Contents alert Volume 19 Issue 12

TABLE OF CONTENTS Volume 19, Issue 12 (December 2011) In this issue Editorial In This Issue Research Highlights Commentaries Original Articles Also new AOP Sign up for e-alerts Recommend to your library Web feed Subscribe Advertisement New to NPG: Molecular Therapy-Nucleic Acids Online. Open Access. High-Quality Research. Molecular Therapy-Nucleic Acids is a sibling journal to the well-established high impact journal, Molecular Therapy. The journal will publish high quality basic, translational, and clinical research and cuttingedge reviews and commentaries targeted to the advances in oligonucleotide- and gene-based therapies. Molecular Therapy-Nucleic Acids is a peer-reviewed, fully open access, online journal. Molecular Therapy-Nucleic Acids is published on behalf of the American Society of Gene & Cell Therapy and NPG. Sign up today for a Molecular Therapy-Nucleic Acids alert.   Editorial Top Gene Therapy for SCID-X1: Focus on Clinical Data Christopher Baum Mol Ther 2011 19: 2103-2104; 10.1038/mt.2011.252 Full Text In This Issue Top In This Issue Mol Ther 2011 19: 2106; 10.1038/mt.2011.246 Full Text Research Highlights Top Research Highlights Mol Ther 2011 19: 2107; 10.1038/mt.2011.247 Full Text Commentaries Top Interfering With Tumor Pathways That Augment Viral Oncolysis John C Bell Mol Ther 2011 19: 2108-2109; 10.1038/mt.2011.253 Full Text lncRNAs: Finding the Forest Among the Trees? Marcel E Dinger Mol Ther 2011 19: 2109-2111; 10.1038/mt.2011.251 Full Text Gene Transfer Using HACs: A Key Step Closer to Ex Vivo Gene Therapy Using Autologous Gene–Corrected Cells to Treat Muscular Dystrophy Jacques P Tremblay and Robert M Frederickson Mol Ther 2011 19: 2111-2113; 10.1038/mt.2011.254 Full Text Original Articles Top ATP7A Gene Addition to the Choroid Plexus Results in Long-term Rescue of the Lethal Copper Transport Defect in a Menkes Disease Mouse Model Anthony Donsante, Ling Yi, Patricia M Zerfas, Lauren R Brinster, Patricia Sullivan, David S Goldstein, Joseph Prohaska, Jose A Centeno, Elisabeth Rushing and Stephen G Kaler Mol Ther 2011 19: 2114-2123; advance online publication, August 30, 2011; 10.1038/mt.2011.143 Abstract | Full Text Co-operative Membrane Disruption Between Cell-penetrating Peptide and Cargo: Implications for the Therapeutic Use of the Bcl-2 Converter Peptide D-NuBCP-9-r8 Catherine L Watkins, Edward J Sayers, Chris Allender, David Barrow, Christopher Fegan, Paul Brennan and Arwyn T Jones Mol Ther 2011 19: 2124-2132; advance online publication, September 20, 2011; 10.1038/mt.2011.175 Abstract | Full Text PiggyBac-mediated Cancer Immunotherapy Using EBV-specific Cytotoxic T-cells Expressing HER2-specific Chimeric Antigen Receptor Yozo Nakazawa, Leslie E Huye, Vita S Salsman, Ann M Leen, Nabil Ahmed, Lisa Rollins, Gianpietro Dotti, Stephen M Gottschalk, Matthew H Wilson and Cliona M Rooney Mol Ther 2011 19: 2133-2143; advance online publication, July 19, 2011; 10.1038/mt.2011.131 Abstract | Full Text Microarray Analysis of Gene Expression Profiles in Cells Transfected With Nonviral Vectors Sarah A Plautz, Gina Boanca, Jean-Jack M Riethoven and Angela K Pannier Mol Ther 2011 19: 2144-2151; advance online publication, August 9, 2011; 10.1038/mt.2011.161 Abstract | Full Text Preclinical Safety of RNAi-Mediated HTT Suppression in the Rhesus Macaque as a Potential Therapy for Huntington's Disease Jodi L McBride, Mark R Pitzer, Ryan L Boudreau, Brett Dufour, Theodore Hobbs, Sergio R Ojeda and Beverly L Davidson Mol Ther 2011 19: 2152-2162; advance online publication, October 25, 2011; 10.1038/mt.2011.219 Abstract | Full Text Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense Sterghios A Moschos, Manfred Frick, Bruce Taylor, Paul Turnpenny, Helen Graves, Karen G Spink, Kevin Brady, David Lamb, David Collins, Thomas D Rockel, Markus Weber, Ovadia Lazari, Luis Perez-Tosar, Sally A Fancy, Chris Lapthorn, Martin X Green, Steve Evans, Matthew Selby, Gareth Jones, Lyn Jones, Sarah Kearney, Houria Mechiche, Diana Gikunju, Romesh Subramanian, Eugen Uhlmann, Marion Jurk, Jörg Vollmer, Giuseppe Ciaramella and Michael Yeadon Mol Ther 2011 19: 2163-2168; advance online publication, October 4, 2011; 10.1038/mt.2011.206 Abstract | Full Text Rational Design of Therapeutic siRNAs: Minimizing Off-targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease Ryan L Boudreau, Ryan M Spengler and Beverly L Davidson Mol Ther 2011 19: 2169-2177; advance online publication, September 27, 2011; 10.1038/mt.2011.185 Abstract | Full Text Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin Jeffrey B Carroll, Simon C Warby, Amber L Southwell, Crystal N Doty, Sarah Greenlee, Niels Skotte, Gene Hung, C Frank Bennett, Susan M Freier and Michael R Hayden Mol Ther 2011 19: 2178-2185; advance online publication, October 4, 2011; 10.1038/mt.2011.201 Abstract | Full Text Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells Genc Basha, Tatiana I Novobrantseva, Nicole Rosin, Yuen Yi C Tam, Ismail M Hafez, Matthew K Wong, Tsukasa Sugo, Vera M Ruda, June Qin, Boris Klebanov, Marco Ciufolini, Akin Akinc, Ying K Tam, Michael J Hope and Pieter R Cullis Mol Ther 2011 19: 2186-2200; advance online publication, October 4, 2011; 10.1038/mt.2011.190 Abstract | Full Text Selective Therapeutic Targeting of the Anaplastic Lymphoma Kinase With Liposomal siRNA Induces Apoptosis and Inhibits Angiogenesis in Neuroblastoma Daniela Di Paolo, Chiara Ambrogio, Fabio Pastorino, Chiara Brignole, Cinzia Martinengo, Roberta Carosio, Monica Loi, Gabriella Pagnan, Laura Emionite, Michele Cilli, Domenico Ribatti, Theresa M Allen, Roberto Chiarle, Mirco Ponzoni and Patrizia Perri Mol Ther 2011 19: 2201-2212; advance online publication, August 9, 2011; 10.1038/mt.2011.142 Abstract | Full Text Efficient In Vivo Delivery of siRNA Into Brain Capillary Endothelial Cells Along With Endogenous Lipoprotein Hiroya Kuwahara, Kazutaka Nishina, Kie Yoshida, Tomoko Nishina, Mariko Yamamoto, Yukari Saito, Wenying Piao, Masayuki Yoshida, Hidehiro Mizusawa and Takanori Yokota Mol Ther 2011 19: 2213-2221; advance online publication, September 13, 2011; 10.1038/mt.2011.186 Abstract | Full Text Stabilization of Expanded (CTG)•(CAG) Repeats by Antisense Oligonucleotides Masayuki Nakamori, Geneviève Gourdon and Charles A Thornton Mol Ther 2011 19: 2222-2227; advance online publication, October 4, 2011; 10.1038/mt.2011.191 Abstract | Full Text Systemic Administration of Combinatorial dsiRNAs via Nanoparticles Efficiently Suppresses HIV-1 Infection in Humanized Mice Jiehua Zhou, C Preston Neff, Xiaoxuan Liu, Jane Zhang, Haitang Li, David D Smith, Piotr Swiderski, Tawfik Aboellail, Yuanyu Huang, Quan Du, Zicai Liang, Ling Peng, Ramesh Akkina and John J Rossi Mol Ther 2011 19: 2228-2238; advance online publication, September 27, 2011; 10.1038/mt.2011.207 Abstract | Full Text Combining mTor Inhibitors With Rapamycin-resistant T Cells: A Two-pronged Approach to Tumor Elimination Leslie E Huye, Yozo Nakazawa, Mayuri P Patel, Eric Yvon, Jiali Sun, Barbara Savoldo, Matthew H Wilson, Gianpietro Dotti and Cliona M Rooney Mol Ther 2011 19: 2239-2248; advance online publication, August 30, 2011; 10.1038/mt.2011.179 Abstract | Full Text The Development of a Novel Cancer Immunotherapeutic Platform Using Tumor-targeting Mesenchymal Stem Cells and a Protein Vaccine Hon-Jian Wei, Alexander TH Wu, Chung-Huei Hsu, Yi-Ping Lin, Wen-Fang Cheng, Ching-Hua Su, Wen-Ta Chiu, Jacqueline Whang-Peng, Frank L Douglas and Win-Ping Deng Mol Ther 2011 19: 2249-2257; advance online publication, July 26, 2011; 10.1038/mt.2011.152 Abstract | Full Text Cytotoxic T Lymphocytes Simultaneously Targeting Multiple Tumor-associated Antigens to Treat EBV Negative Lymphoma Ulrike Gerdemann, Usha Katari, Anne S Christin, Conrad R Cruz, Tamara Tripic, Alexandra Rousseau, Stephen M Gottschalk, Barbara Savoldo, Juan F Vera, Helen E Heslop, Malcolm K Brenner, Catherine M Bollard, Cliona M Rooney and Ann M Leen Mol Ther 2011 19: 2258-2268; advance online publication, September 13, 2011; 10.1038/mt.2011.167 Abstract | Full Text Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors Susanne H Sheehy, Christopher JA Duncan, Sean C Elias, Katharine A Collins, Katie J Ewer, Alexandra J Spencer, Andrew R Williams, Fenella D Halstead, Samuel E Moretz, Kazutoyo Miura, Christian Epp, Matthew DJ Dicks, Ian D Poulton, Alison M Lawrie, Eleanor Berrie, Sarah Moyle, Carole A Long, Stefano Colloca, Riccardo Cortese, Sarah C Gilbert, Alfredo Nicosia, Adrian VS Hill and Simon J Draper Mol Ther 2011 19: 2269-2276; advance online publication, August 23, 2011; 10.1038/mt.2011.176 Abstract | Full Text Advertisement Be part of the research that is changing the course of medicine! 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