Nature Reviews Microbiology contents November 2011 Volume 9 Number 11 pp 761-828

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TABLE OF CONTENTS
November 2011 Volume 9 Number 11
Impact Factor 20.686 * Subscribe to Nature Reviews Microbiology Recommend to your library	In this issue Comment Research Highlights News and Analysis Progress Reviews Also this month  Featured article: Regulation of growth and death in Escherichia coli by toxin–antitoxin systems Yoshihiro Yamaguchi & Masayori Inouye
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In this issue p761 | doi:10.1038/nrmicro2685 Full Text
Comment: Virophages or satellite viruses? Mart Krupovic & Virginija Cvirkaite-Krupovic p762 | doi:10.1038/nrmicro2676 Abstract | Full Text | PDF
RESEARCH HIGHLIGHTS Top Innate immunity: NAIPs give pathogens a warm reception p765 | doi:10.1038/nrmicro2678 Two research groups have now identified NAIP proteins as substrate-specific receptors for the NLRC4 inflammasome. PDF Fungal pathogenesis: Hungry fungus eats nematode p766 | doi:10.1038/nrmicro2674 The genome sequence and subsequent transcriptomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insight into the carnivorous lifestyle of such nematophagous fungi. PDF IN BRIEF Fungal genetics: Killer sought in case of missing RNA interference p766 | doi:10.1038/nrmicro2681 PDF Host response: Probiotic ingestion alters mood p766 | doi:10.1038/nrmicro2686 PDF Structural biology: Gamers solve monkey virus puzzle p766 | doi:10.1038/nrmicro2687 PDF Virology: Unusual escape for HCMV p766 | doi:10.1038/nrmicro2682 A new paper reveals that HCMV can escape a neutralizing antibody by incorporating it into assembling virions. PDF Antimicrobials: Disruption of quorum sensing meets resistance p767 | doi:10.1038/nrmicro2679 Targeting virulence mechanisms rather than growth does not prevent resistance in bacterial pathogens. PDF Bacterial toxins: Breaking the barrier p768 | doi:10.1038/nrmicro2672 Binding of α-haemolysin to ADAM10 leads to epithelial barrier disruption during S. aureus infection. PDF Bacterial physiology: LCP proteins take the final step p768 | doi:10.1038/nrmicro2684 A recent paper identifies a new protein family involved in bacterial cell wall assembly. PDF Microbiology JOBS of the week Junior Fellows Program Howard Hughes Medical Institute Ashburn, US Faculty and Post-Doctoral Research Associates Kyushu University Fukuoka Shi, JP Faculty Appointment in Neurobiology Duke University Durham, US W3-Professur fur Vaskulare Neurologie Universitat Heidelberg Heidelberg, DE Lab Heads Howard Hughes Medical Institute Ashburn, US More Science jobs from Microbiology EVENT Innate Immunity: Sensing the Microbes and Damage Signals (Q7) joint with The Microbiome (Q8) 04.-09.03.12 Colorado, US More science events from
NEWS AND ANALYSIS		Top
GENOME WATCH A new piece of the eukaryotic puzzle Alejandro Sanchez-Flores p769 | doi:10.1038/nrmicro2680 This month's Genome Watch discusses the genome of the free-living amoeboflagellate protist Naegleria gruberi. PDF
DISEASE WATCH In the news p770 | doi:10.1038/nrmicro2683 Our monthly round-up of infectious diseases news, which this month includes the Lasker Award for the discovery of artemisinin, the discovery of a new tick-borne disease and the development of a new tuberculosis vaccine. PDF
PROGRESS		Top
De novo generation of prion strains David W. Colby & Stanley B. Prusiner p771 | doi:10.1038/nrmicro2650 Prions are infectious self-replicating proteins that can cause neurodegenerative disorders such as bovine spongiform encephalopathy. Here, Colby and Prusiner discuss recent advances in the generation of synthetic prion strains that may lead to new insights into the structure of prions and the mechanisms by which they originate and propagate. Abstract | Full Text | PDF
REVIEWS		Top
Regulation of growth and death in Escherichia coli by toxin–antitoxin systems Yoshihiro Yamaguchi & Masayori Inouye p779 | doi:10.1038/nrmicro2651 Under normal conditions, the components of a toxin–antitoxin (TA) system form a stable complex, blocking toxin activity. However, when the cell is stressed, the antitoxin is degraded, freeing the toxin to cause damage. Here, Yamaguchi and Inouye describe the TA systems found in Escherichia coli and their role in regulating cell growth and death. Abstract | Full Text | PDF
Microbial ultraviolet sunscreens Qunjie Gao & Ferran Garcia-Pichel p791 | doi:10.1038/nrmicro2649 Many microorganisms produce secondary metabolites to protect their molecular constituents from the damaging effects of ultraviolet radiation. Here, Gao and Garcia-Pichel describe our current understanding of the best known examples of these microbial ultraviolet sunscreens, including their biosynthesis, regulation and potential applications. Abstract | Full Text | PDF | Supplementary information
Microbial degradation of aromatic compounds — from one strategy to four Georg Fuchs, Matthias Boll & Johann Heider p803 | doi:10.1038/nrmicro2652 Until recently, it was thought that the microbial degradation of aromatic compounds was absolutely dependent on the use of molecular oxygen for ring cleavage. However, as described here by Fuchs and colleagues, microorganisms have other ways of breaking down these compounds when oxygen is scarce or absent. Abstract | Full Text | PDF
Non-transcriptional regulatory processes shape transcriptional network dynamics J. Christian J. Ray, Jeffrey J. Tabor & Oleg A. Igoshin p817 | doi:10.1038/nrmicro2667 Non-transcriptional events can have a large effect on the dynamics of regulatory processes. Here, Ray, Tabor and Igoshin describe how post-transcriptional and post-translational events can affect the performance of regulatory processes in bacteria. Abstract | Full Text | PDF | Supplementary information
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*2010 Journal Citation Report (Thomson Reuters, 2011)

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