TABLE OF CONTENTS
|  |  |  | Volume 19, Issue 10 (October 2011) |  | In this issue
Editorial
In This Issue
Research Highlights
Commentaries
Reviews
Original Articles
Also new
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|  | | | Editorial | Top |  | Cell Phones and Landlines: The Impact of Gene Therapy on the Cost and Availability of Treatment for HemophiliaKatherine A High and Mark W Skinner Mol Ther 2011 19: 1749-1750; 10.1038/mt.2011.203 Full Text |  | In This Issue | Top |  | In This IssueMol Ther 2011 19: 1752; 10.1038/mt.2011.199 Full Text |  | Research Highlights | Top |  | Research HighlightsMol Ther 2011 19: 1753; 10.1038/mt.2011.200 Full Text |  | Commentaries | Top |  | Intranasal Exosomes for Treatment of Neuroinflammation?: Prospects and LimitationsSamira Lakhal and Matthew JA Wood Mol Ther 2011 19: 1754-1756; 10.1038/mt.2011.198 Full Text |  |  |  | Bridge Over Troubled stem cellsGrant A Challen and Margaret A Goodell Mol Ther 2011 19: 1756-1758; 10.1038/mt.2011.184 Full Text |  | Reviews | Top |  | Insulin-producing Surrogate β-cells From Embryonic Stem Cells: Are We There Yet?Ortwin Naujok, Chris Burns, Peter M Jones and Sigurd Lenzen Mol Ther 2011 19: 1759-1768; advance online publication, August 9, 2011; 10.1038/mt.2011.165 Abstract | Full Text |  | Original Articles | Top |  | Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the BrainXiaoying Zhuang, Xiaoyu Xiang, William Grizzle, Dongmei Sun, Shuangqin Zhang, Robert C Axtell, Songwen Ju, Jiangyao Mu, Lifeng Zhang, Lawrence Steinman, Donald Miller and Huang-Ge Zhang Mol Ther 2011 19: 1769-1779; advance online publication, September 13, 2011; 10.1038/mt.2011.164 Abstract | Full Text |  |  |  | Perturbing PSD-95 Interactions With NR2B-subtype Receptors Attenuates Spinal Nociceptive Plasticity and Neuropathic PainRichard D'Mello, Fabien Marchand, Sophie Pezet, Stephen B McMahon and Anthony H Dickenson Mol Ther 2011 19: 1780-1792; advance online publication, March 22, 2011; 10.1038/mt.2011.42 Abstract | Full Text |  |  |  | Combined Flt3L/TK Gene Therapy Induces Immunological Surveillance Which Mediates an Immune Response Against a Surrogate Brain Tumor NeoantigenGwendalyn D King, AKM Ghulam Muhammad, Daniel Larocque, Kyle R Kelson, Weidong Xiong, Chunyan Liu, Nicholas SR Sanderson, Kurt M Kroeger, Maria G Castro and Pedro R Lowenstein Mol Ther 2011 19: 1793-1801; advance online publication, April 19, 2011; 10.1038/mt.2011.77 Abstract | Full Text |  |  |  | Precise Scheduling of Chemotherapy Primes VEGF-producing Tumors for Successful Systemic Oncolytic VirotherapyTimothy Kottke, John Chester, Elizabeth Ilett, Jill Thompson, Rosa Diaz, Matt Coffey, Peter Selby, Gerard Nuovo, Jose Pulido, Debabrata Mukhopadhyay, Hardev Pandha, Kevin Harrington, Alan Melcher and Richard Vile Mol Ther 2011 19: 1802-1812; advance online publication, July 26, 2011; 10.1038/mt.2011.147 Abstract | Full Text |  |  |  | Envelope-chimeric Entry-targeted Measles Virus Escapes Neutralization and Achieves OncolysisTanner S Miest, Koon-Chu Yaiw, Marie Frenzke, Johanna Lampe, Andrew W Hudacek, Christoph Springfeld, Veronika von Messling, Guy Ungerechts and Roberto Cattaneo Mol Ther 2011 19: 1813-1820; advance online publication, May 24, 2011; 10.1038/mt.2011.92 Abstract | Full Text |  |  |  | Age-dependent Dystrophin Loss and Genetic Reconstitution Establish a Molecular Link Between Dystrophin and Heart Performance During AgingDeWayne Townsend, Michael Daly, Jeffrey S Chamberlain and Joseph M Metzger Mol Ther 2011 19: 1821-1825; advance online publication, July 5, 2011; 10.1038/mt.2011.120 Abstract | Full Text |  |  |  | AAV-microdystrophin Therapy Improves Cardiac Performance in Aged Female mdx MiceBrian Bostick, Jin-Hong Shin, Yongping Yue and Dongsheng Duan Mol Ther 2011 19: 1826-1832; advance online publication, August 2, 2011; 10.1038/mt.2011.154 Abstract | Full Text |  |  |  | Expression of Apolipoprotein A-I in Rabbit Carotid Endothelium Protects Against AtherosclerosisRowan Flynn, Kun Qian, Chongren Tang, Nagadhara Dronadula, Joshua M Buckler, Bo Jiang, Shan Wen, Helén L Dichek and David A Dichek Mol Ther 2011 19: 1833-1841; advance online publication, July 19, 2011; 10.1038/mt.2011.133 Abstract | Full Text |  |  |  | Large-volume Intrathecal Enzyme Delivery Increases Survival of a Mouse Model of Late Infantile Neuronal Ceroid LipofuscinosisSu Xu, Lingling Wang, Mukarram El-Banna, Istvan Sohar, David E Sleat and Peter Lobel Mol Ther 2011 19: 1842-1848; advance online publication, July 5, 2011; 10.1038/mt.2011.130 Abstract | Full Text |  |  |  | A Cell-penetrating Peptide Suppresses Inflammation by Inhibiting NF-κB SignalingYu Fu Wang, Xiang Xu, Xia Fan, Chun Zhang, Qiang Wei, Xi Wang, Wei Guo, Wei Xing, Jian Yu, Jing-Long Yan and Hua-Ping Liang Mol Ther 2011 19: 1849-1857; advance online publication, May 10, 2011; 10.1038/mt.2011.82 Abstract | Full Text |  |  |  | Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic AdenovirusIlkka Liikanen, Vladia Monsurrò, Laura Ahtiainen, Mari Raki, Tanja Hakkarainen, Iulia Diaconu, Sophie Escutenaire, Otto Hemminki, João D Dias, Vincenzo Cerullo, Anna Kanerva, Sari Pesonen, Daniela Marzioni, Marco Colombatti and Akseli Hemminki Mol Ther 2011 19: 1858-1866; advance online publication, July 26, 2011; 10.1038/mt.2011.144 Abstract | Full Text |  |  |  | Correction of Murine SCID-X1 by Lentiviral Gene Therapy Using a Codon-optimized IL2RG Gene and Minimal Pretransplant ConditioningMarshall W Huston, Niek P van Til, Trudi P Visser, Shazia Arshad, Martijn H Brugman, Claudia Cattoglio, Ali Nowrouzi, Yuedan Li, Axel Schambach, Manfred Schmidt, Christopher Baum, Christof von Kalle, Fulvio Mavilio, Fang Zhang, Mike P Blundell, Adrian J Thrasher, Monique MA Verstegen and Gerard Wagemaker Mol Ther 2011 19: 1867-1877; advance online publication, July 12, 2011; 10.1038/mt.2011.127 Abstract | Full Text |  |  |  | Targeting 4-1BB Costimulation to Disseminated Tumor Lesions With Bi-specific Oligonucleotide AptamersFernando Pastor, Despina Kolonias, James O McNamara II and Eli Gilboa Mol Ther 2011 19: 1878-1886; advance online publication, August 9, 2011; 10.1038/mt.2011.145 Abstract | Full Text |  |  |  | Alternative for Anti-TNF Antibodies for Arthritis TreatmentJoseph Paquet, Christel Henrionnet, Astrid Pinzano, Jean-Baptiste Vincourt, Pierre Gillet, Patrick Netter, Isabelle Chary-Valckenaere, Damien Loeuille, Jacques Pourel and Laurent Grossin Mol Ther 2011 19: 1887-1895; advance online publication, August 2, 2011; 10.1038/mt.2011.156 Abstract | Full Text |  |  |  | Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic Dendritic CellsRui-Jun Su, Angela Epp, Junli Feng, Jackie Roy, Yvette Latchman, Xiaoping Wu, Doug Bolgiano and Neil C Josephson Mol Ther 2011 19: 1896-1904; advance online publication, July 19, 2011; 10.1038/mt.2011.134 Abstract | Full Text |  |  |  | Rapid and Efficient Generation of Functional Motor Neurons From Human Pluripotent Stem Cells Using Gene Delivered Transcription Factor CodesMark E Hester, Matthew J Murtha, SungWon Song, Meghan Rao, Carlos J Miranda, Kathrin Meyer, Jinbin Tian, Gabriella Boulting, David V Schaffer, Michael X Zhu, Samuel L Pfaff, Fred H Gage and Brian K Kaspar Mol Ther 2011 19: 1905-1912; advance online publication, July 19, 2011; 10.1038/mt.2011.135 Abstract | Full Text |  |  |  | A Mechanistic Proof-of-concept Clinical Trial With JX-594, a Targeted Multi-mechanistic Oncolytic Poxvirus, in Patients With Metastatic MelanomaTae-Ho Hwang, Anne Moon, James Burke, Antoni Ribas, Joe Stephenson, Caroline J Breitbach, Manijeh Daneshmand, Naomi De Silva, Kelley Parato, Jean-Simon Diallo, Yeon-Sook Lee, Ta-Chiang Liu, John C Bell and David H Kirn Mol Ther 2011 19: 1913-1922; advance online publication, July 19, 2011; 10.1038/mt.2011.132 Abstract | Full Text |  |  |  |  |  | Be part of the research that is changing the course of medicine! 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