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View Table of Contents http://links.ealert.nature.com/ctt?kn=31&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
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---THIS WEEK'S HIGHLIGHTS:
--Biological Sciences
-Impacts of biodiversity on the emergence and transmission of
infectious diseases
Ecosystem biodiversity reduces the incidence of infectious disease
in plants and animals - including humans.
[ http://links.ealert.nature.com/ctt?kn=73&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0 ]
--Physical Sciences
-A ground-based transmission spectrum of the super-Earth exoplanet GJ 1214b
A team using the Very Large Telescope in Chile has obtained a transmission
spectrum for a 'super-Earth' planet, revealing details of its atmosphere.
Their new observing technique will make observation of extrasolar planets
a much more practical proposition in future.
[ http://links.ealert.nature.com/ctt?kn=76&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0 ]
--Biological Sciences
-Acid sensing by the Drosophila olfactory system
We all know that acids produce an irritating odour, but until now no
acid sensing neurons have been found in the olfactory system. Now they
have been discovered - in the olfactory system of the fruitfly.
[ http://links.ealert.nature.com/ctt?kn=70&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0 ]
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=====================================================================
--Podcast & Video
-In this weeks podcast: we reverse the ageing process, study the
blueprints of an underwater electricity grid and round up Nature's
most important protein structures from 2010. Plus, our pick of
what's hot from this week's Nature
[ http://links.ealert.nature.com/ctt?kn=103&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0 ]
======================== NEWS AND COMMENT ========================
Read daily news coverage http://links.ealert.nature.com/ctt?kn=90&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
EDITORIALS
** An end to gridlock?
Europe says it is embarking on an unprecedented overhaul of its
electricity system. But it must do more to convince the private
sector that it is serious.
http://links.ealert.nature.com/ctt?kn=72&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** A long way to go
Overpriced and underused, the International Space Station could
still be a research asset.
http://links.ealert.nature.com/ctt?kn=80&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Undue obstruction
Republican opposition to the US-Russia arms-control treaty is based
on politics, not science.
http://links.ealert.nature.com/ctt?kn=81&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
WORLD VIEW
** A sustainable planet needs scientists to think ahead
Globalization means that Earth's life-support system can no longer
be treated as separate from the socio–economic system,
says Sybil Seitzinger.
http://links.ealert.nature.com/ctt?kn=104&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
SEVEN DAYS
** Seven days: 2 December 2010
The week in science
http://links.ealert.nature.com/ctt?kn=111&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
NEWS
** Iranian nuclear scientists attacked
Murder and cyber-assault target nuclear programme.
http://links.ealert.nature.com/ctt?kn=122&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Complex synthesis yields breast-cancer therapy
Drug approval marks culmination of a marathon trek from sea sponges
to clinic.
http://links.ealert.nature.com/ctt?kn=112&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Physics centre plans rapid growth
Perimeter Institute steps up drive to attract top talent.
http://links.ealert.nature.com/ctt?kn=118&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Partners wanted to run research lab in space
NASA seeks wider research-community involvement in the International
Space Station.
http://links.ealert.nature.com/ctt?kn=109&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** India blocks nuclear meeting
Fission group is 'hostile to India', government claims.
http://links.ealert.nature.com/ctt?kn=110&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Chemists help archaeologists to probe biblical history
Collaboration establishes a new approach for teasing out clues hidden
in the soil.
http://links.ealert.nature.com/ctt?kn=107&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
FEATURES
** Stem cells: The impatient advocate
Bob Klein founded the California Institute for Regenerative Medicine,
the biggest state-run research project in US history. What legacy
will he leave behind?
http://links.ealert.nature.com/ctt?kn=108&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Energy: Supergrid
Is a vast undersea grid bringing wind-generated electricity from the
North Sea to Europe a feasible proposition or an overpriced fantasy?
http://links.ealert.nature.com/ctt?kn=105&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
COMMENT
** Follow the money
What was the impact of the nanotechnology funding boom of the past
ten years? Philip Shapira and Jue Wang have scrutinized the
literature to find out.
http://links.ealert.nature.com/ctt?kn=77&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
BOOKS AND ARTS
** Biography: Envy and power
A balanced biography brings out the many contradictions of nuclear
physicist Edward Teller, finds Robert P. Crease.
http://links.ealert.nature.com/ctt?kn=79&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Neuroscience: Patterns from the brain
Vincent A. Billock recommends an introduction to the mathematics of
geometric hallucinations.
http://links.ealert.nature.com/ctt?kn=67&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Books in brief
http://links.ealert.nature.com/ctt?kn=55&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** History: How to behave beyond the grave
Instructions for the afterlife from Ancient Egypt reveal a step
change in moral psychology, discovers Andrew Robinson.
http://links.ealert.nature.com/ctt?kn=54&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Technology: Libraries of the future
A hands-on exhibition shows how online tools are shaping the way
we use knowledge, says Aleks Krotoski.
http://links.ealert.nature.com/ctt?kn=58&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
CORRESPONDENCE
** Archiving lessons from radiobiology
Paul N. Schofield, Soile Tapio and Bernd Grosche
http://links.ealert.nature.com/ctt?kn=57&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** The politics of climate (dis)belief
Francis Nicholson
http://links.ealert.nature.com/ctt?kn=60&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** How to conserve the tropics as they warm
Jedediah Brodie, Eric Post and William Laurance
http://links.ealert.nature.com/ctt?kn=59&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Faraday on the fiscal benefits of science
Michael Polymenis
http://links.ealert.nature.com/ctt?kn=62&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
=========================== ADVERTISEMENT ===========================
Royal Society medals and awards 2011 - Call for nominations open
http://links.ealert.nature.com/ctt?kn=17&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
The Royal Society's medals, awards and prize lectureships provide an
opportunity to celebrate excellence in science. We invite you to
nominate scientists who have made outstanding achievements.
The deadline for nominations is Monday 14 February 2011.
For more information please visit:
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=====================================================================
======================== BIOLOGICAL SCIENCES ========================
RESEARCH
** Lkb1 regulates cell cycle and energy metabolism in haematopoietic
stem cells
Daisuke Nakada, Thomas L. Saunders and Sean J. Morrison
Little is known about metabolic regulation in stem cells and how
this modulates...
http://links.ealert.nature.com/ctt?kn=61&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
Sushma Gurumurthy, Stephanie Z. Xie, Brinda Alagesan, Judith Kim,
Rushdia Z. Yusuf et al.
Haematopoietic stem cells (HSCs) can convert between growth states
that have ma...
http://links.ealert.nature.com/ctt?kn=97&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation
Daisuke Kaida, Michael G. Berg, Ihab Younis, Mumtaz Kasim,
Larry N. Singh et al.
In eukaryotes, U1 small nuclear ribonucleoprotein (snRNP) forms s
pliceosomes in...
http://links.ealert.nature.com/ctt?kn=98&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** A dimorphic pheromone circuit in Drosophila from sensory input to
descending output
Vanessa Ruta, Sandeep Robert Datta, Maria Luisa Vasconcelos,
Jessica Freeland, Loren L. Looger et al.
Drosophila show innate olfactory-driven behaviours that are observed
in naive a...
http://links.ealert.nature.com/ctt?kn=78&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Acid sensing by the Drosophila olfactory system
Minrong Ai, Soohong Min, Yael Grosjean, Charlotte Leblanc,
Rati Bell et al.
The odour of acids has a distinct quality that is perceived as sharp,
pungent a...
http://links.ealert.nature.com/ctt?kn=70&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Oxidant stress evoked by pacemaking in dopaminergic neurons is
attenuated by DJ-1
Jaime N. Guzman, Javier Sanchez-Padilla, David Wokosin,
Jyothisri Kondapalli, Ema Ilijic et al.
Parkinson's disease is a pervasive, ageing-related neurodegenerative ...
http://links.ealert.nature.com/ctt?kn=89&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic
stem cells
Boyi Gan, Jian Hu, Shan Jiang, Yingchun Liu, Ergun Sahin et al.
The capacity to fine-tune cellular bioenergetics with the demands of
stem-cell ...
http://links.ealert.nature.com/ctt?kn=86&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Structural changes of envelope proteins during alphavirus fusion
Long Li, Joyce Jose, Ye Xiang, Richard J. Kuhn and Michael G. Rossmann
Alphaviruses are enveloped RNA viruses that have a diameter of about ...
http://links.ealert.nature.com/ctt?kn=84&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Glycoprotein organization of Chikungunya virus particles revealed
by X-ray crystallography
James E. Voss, Marie-Christine Vaney, Stephane Duquerroy,
Clemens Vonrhein, Christine Girard-Blanc et al.
Chikungunya virus (CHIKV) is an emerging mosquito-borne alphavirus
that has cau...
http://links.ealert.nature.com/ctt?kn=82&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Head swivel on the ribosome facilitates translocation by means of
intra-subunit tRNA hybrid sites
Andreas H. Ratje, Justus Loerke, Aleksandra Mikolajka, Matthias Brunner,
Peter W. Hildebrand et al.
The elongation cycle of protein synthesis involves the delivery of
aminoacyl-tr...
http://links.ealert.nature.com/ctt?kn=95&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Structure and mechanism of the S component of a bacterial ECF
transporter
Peng Zhang, Jiawei Wang and Yigong Shi
The energy-coupling factor (ECF) transporters, responsible for
vitamin uptake i...
http://links.ealert.nature.com/ctt?kn=93&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Crystal structure of bacterial RNA polymerase bound with a
transcription inhibitor protein
Shunsuke Tagami, Shun-ichi Sekine, Thirumananseri Kumarevel,
Nobumasa Hino, Yuko Murayama et al.
The multi-subunit DNA-dependent RNA polymerase (RNAP) is the principal
enzyme o...
http://links.ealert.nature.com/ctt?kn=92&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Integrative genomics identifies LMO1 as a neuroblastoma oncogene
Kai Wang, Sharon J. Diskin, Haitao Zhang, Edward F. Attiyeh,
Cynthia Winter et al.
Neuroblastoma is a childhood cancer of the sympathetic nervous system
that acco...
http://links.ealert.nature.com/ctt?kn=91&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou, Amir S. Yazdi, Philippe Menu and Jurg Tschopp
An inflammatory response initiated by the NLRP3 inflammasome is
triggered by a ...
http://links.ealert.nature.com/ctt?kn=33&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Reversing EphB2 depletion rescues cognitive functions in Alzheimer
model
Moustapha Cisse, Brian Halabisky, Julie Harris, Nino Devidze,
Dena B. Dubal et al.
Amyloid-[beta] oligomers may cause cognitive deficits in Alzheimer's d...
http://links.ealert.nature.com/ctt?kn=29&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Telomerase reactivation reverses tissue degeneration in aged
telomerase-deficient mice
Mariela Jaskelioff, Florian L. Muller, Ji-Hye Paik, Emily Thomas,
Shan Jiang et al.
An ageing world population has fuelled interest in regenerative
remedies that m...
http://links.ealert.nature.com/ctt?kn=30&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Paneth cells constitute the niche for Lgr5 stem cells in intestinal
crypts
Toshiro Sato, Johan H. van Es, Hugo J. Snippert, Daniel E. Stange,
Robert G. Vries et al.
Homeostasis of self-renewing small intestinal crypts results from
neutral compe...
http://links.ealert.nature.com/ctt?kn=24&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Cancer: Chemotherapy counteracted
Urban Emmenegger and Robert S. Kerbel
Resistance of tumour cells to chemotherapy can severely affect the
efficacy of this anticancer treatment. The non-tumour cells of the organ
in which the tumour resides may aid the emergence of such resistance.
http://links.ealert.nature.com/ctt?kn=26&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Neuroscience: Sexy circuits
Richard Benton
As in humans, the actions and reactions of male and female fruitflies
during courtship are quite distinct. The differences seem to lie in
gender-specific neural interpretations of the same sensory signals.
http://links.ealert.nature.com/ctt?kn=27&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Analytical biochemistry: Weighing up protein folding
Martin Gruebele
Labelling molecules by fast oxidation allows mass spectrometry to study
protein folding at submillisecond time resolution. The method also brings
a wealth of structural information about protein folding within reach.
http://links.ealert.nature.com/ctt?kn=28&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Parasitology: Nematode debt to bacteria
Noah K. Whiteman and Andrew D. Gloss
The transition by certain nematode worms to plant parasitism, and
possibly more generally to herbivory, is illuminated by an
investigation into how nematodes acquired the protein weapons to
penetrate the plant cell wall.
http://links.ealert.nature.com/ctt?kn=20&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Stem cells: The blood balance
Ellen M. Durand and Leonard I. Zon
Blood cells are generated from haematopoietic stem cells on demand.
The protein Lkb1, which lies at the crossroad of energy metabolism
and cell growth, seems to regulate these stem cells' dynamics.
http://links.ealert.nature.com/ctt?kn=21&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Structural biology: An alphavirus puzzle solved
Margaret Kielian
Alphaviruses infect their host by binding to cellular receptors and
fusing with cell membranes. New studies define the receptor-binding
protein of these viruses and its regulation of the membrane-fusion
reaction.
http://links.ealert.nature.com/ctt?kn=22&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Impacts of biodiversity on the emergence and transmission of
infectious diseases
Felicia Keesing, Lisa K. Belden, Peter Daszak, Andrew Dobson,
C. Drew Harvell et al.
Current unprecedented declines in biodiversity reduce the ability of
ecological...
http://links.ealert.nature.com/ctt?kn=73&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
NEWS & COMMENT
** Zoology: Showcasing the sea's strange secrets
http://links.ealert.nature.com/ctt?kn=23&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Geoscience: How plants check global warming
http://links.ealert.nature.com/ctt?kn=46&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Chemistry: Tiny molecular 'water bottle'
http://links.ealert.nature.com/ctt?kn=43&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Medicine: Profiling for blood pressure
http://links.ealert.nature.com/ctt?kn=44&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Stem cells: Platelets get a boost
http://links.ealert.nature.com/ctt?kn=41&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Developmental biology: Placenta key to fetal growth rate
http://links.ealert.nature.com/ctt?kn=42&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Neurobiology: The source of sour taste
http://links.ealert.nature.com/ctt?kn=39&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Cell biology: Genes that make cells move
http://links.ealert.nature.com/ctt?kn=40&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** A long way to go
Overpriced and underused, the International Space Station could still
be a research asset.
http://links.ealert.nature.com/ctt?kn=80&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Neuroscience: Patterns from the brain
Vincent A. Billock recommends an introduction to the mathematics of g
eometric hallucinations.
http://links.ealert.nature.com/ctt?kn=67&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Books in brief
http://links.ealert.nature.com/ctt?kn=55&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** History: How to behave beyond the grave
Instructions for the afterlife from Ancient Egypt reveal a step change
in moral psychology, discovers Andrew Robinson.
http://links.ealert.nature.com/ctt?kn=54&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Archiving lessons from radiobiology
Paul N. Schofield, Soile Tapio and Bernd Grosche
http://links.ealert.nature.com/ctt?kn=57&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** More News & Comment on BIOLOGICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=90&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
=========================== ADVERTISEMENT ===========================
Eppendorf Awards
Nature is the partner for the Eppendorf Award for Young European
Investigators. We invite biological and biomedical researchers of
35 years or under, working in Europe, to apply for the 2011
Eppendorf Award.
The closing date is 15th January 2011.
Apply at http://links.ealert.nature.com/ctt?kn=45&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
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======================== CHEMICAL SCIENCES ========================
RESEARCH
** U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation
Daisuke Kaida, Michael G. Berg, Ihab Younis, Mumtaz Kasim,
Larry N. Singh et al.
In eukaryotes, U1 small nuclear ribonucleoprotein (snRNP) forms
spliceosomes in...
http://links.ealert.nature.com/ctt?kn=98&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Head swivel on the ribosome facilitates translocation by means of
intra-subunit tRNA hybrid sites
Andreas H. Ratje, Justus Loerke, Aleksandra Mikolajka, Matthias Brunner,
Peter W. Hildebrand et al.
The elongation cycle of protein synthesis involves the delivery of
aminoacyl-tr...
http://links.ealert.nature.com/ctt?kn=95&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Structure and mechanism of the S component of a bacterial ECF
transporter
Peng Zhang, Jiawei Wang and Yigong Shi
The energy-coupling factor (ECF) transporters, responsible for
vitamin uptake i...
http://links.ealert.nature.com/ctt?kn=93&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Crystal structure of bacterial RNA polymerase bound with a
transcription inhibitor protein
Shunsuke Tagami, Shun-ichi Sekine, Thirumananseri Kumarevel,
Nobumasa Hino, Yuko Murayama et al.
The multi-subunit DNA-dependent RNA polymerase (RNAP) is the
principal enzyme o...
http://links.ealert.nature.com/ctt?kn=92&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou, Amir S. Yazdi, Philippe Menu and Jurg Tschopp
An inflammatory response initiated by the NLRP3 inflammasome is
triggered by a ...
http://links.ealert.nature.com/ctt?kn=33&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Analytical biochemistry: Weighing up protein folding
Martin Gruebele
Labelling molecules by fast oxidation allows mass spectrometry to
study protein folding at submillisecond time resolution. The method
also brings a wealth of structural information about protein folding
within reach.
http://links.ealert.nature.com/ctt?kn=28&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
NEWS & COMMENT
** Chemistry: Tiny molecular 'water bottle'
http://links.ealert.nature.com/ctt?kn=43&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Optical physics: A peek at a molecule's guts
http://links.ealert.nature.com/ctt?kn=38&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Stem cells: Platelets get a boost
http://links.ealert.nature.com/ctt?kn=41&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** More News & Comment on CHEMICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=90&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
======================== PHYSICAL SCIENCES ========================
RESEARCH
** A ground-based transmission spectrum of the super-Earth exoplanet
GJ 1214b
Jacob L. Bean, Eliza Miller-Ricci Kempton and Derek Homeier
In contrast to planets with masses similar to that of Jupiter and
higher, the b...
http://links.ealert.nature.com/ctt?kn=76&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Trapped antihydrogen
G. B. Andresen, M. D. Ashkezari, M. Baquero-Ruiz, W. Bertsche,
P. D. Bowe et al.
Antimatter was first predicted in 1931, by Dirac. Work with
high-energy antipar...
http://links.ealert.nature.com/ctt?kn=34&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Fluctuating stripes at the onset of the pseudogap in the high-T c
superconductor Bi2Sr2CaCu2O8+x
Colin V. Parker, Pegor Aynajian, Eduardo H. da Silva Neto,
Aakash Pushp, Shimpei Ono et al.
Doped Mott insulators have a strong propensity to form patterns of
holes and sp...
http://links.ealert.nature.com/ctt?kn=9&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** A substantial population of low-mass stars in luminous elliptical
galaxies
Pieter G. van Dokkum and Charlie Conroy
The stellar initial mass function (IMF) describes the mass distribution
of star...
http://links.ealert.nature.com/ctt?kn=10&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Planetary science: A cloudy view of exoplanets
Drake Deming
The lack of absorption features in the transmission spectrum of
exoplanet GJ 1214b rules out a hydrogen-rich atmosphere for the
planet. It is consistent with an atmosphere rich in water vapour
or abundant in clouds.
http://links.ealert.nature.com/ctt?kn=11&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** High-temperature superconductivity: How the cuprates hid their
stripes
Kathryn A. Moler
Extensive mapping of local electronic structure in copper oxide
superconductors reveals fluctuating stripe-like electron patterns
that appear as a high-temperature precursor to superconductivity.
http://links.ealert.nature.com/ctt?kn=12&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
NEWS & COMMENT
** Geoscience: How plants check global warming
http://links.ealert.nature.com/ctt?kn=46&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Optical physics: A peek at a molecule's guts
http://links.ealert.nature.com/ctt?kn=38&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Materials: Controlling water on synthetic silk
http://links.ealert.nature.com/ctt?kn=1&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** An end to gridlock?
Europe says it is embarking on an unprecedented overhaul of its
electricity system. But it must do more to convince the private
sector that it is serious.
http://links.ealert.nature.com/ctt?kn=72&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** A long way to go
Overpriced and underused, the International Space Station could
still be a research asset.
http://links.ealert.nature.com/ctt?kn=80&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Undue obstruction
Republican opposition to the US-Russia arms-control treaty is based
on politics, not science.
http://links.ealert.nature.com/ctt?kn=81&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Follow the money
What was the impact of the nanotechnology funding boom of the past
ten years? Philip Shapira and Jue Wang have scrutinized the
literature to find out.
http://links.ealert.nature.com/ctt?kn=77&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Biography: Envy and power
A balanced biography brings out the many contradictions of nuclear
physicist Edward Teller, finds Robert P. Crease.
http://links.ealert.nature.com/ctt?kn=79&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Books in brief
http://links.ealert.nature.com/ctt?kn=55&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** The politics of climate (dis)belief
Francis Nicholson
http://links.ealert.nature.com/ctt?kn=60&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** More News & Comment on PHYSICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=90&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
======================== EARTH AND ENVIRONMENTAL SCIENCES ========================
RESEARCH
** A ground-based transmission spectrum of the super-Earth exoplanet
GJ 1214b
Jacob L. Bean, Eliza Miller-Ricci Kempton and Derek Homeier
In contrast to planets with masses similar to that of Jupiter and
higher, the b...
http://links.ealert.nature.com/ctt?kn=76&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** The redox state of arc mantle using Zn/Fe systematics
Cin-Ty A. Lee, Peter Luffi, Veronique Le Roux, Rajdeep Dasgupta,
Francis Albarede et al.
Many arc lavas are more oxidized than mid-ocean-ridge basalts and
subduction in...
http://links.ealert.nature.com/ctt?kn=3&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Planetary science: A cloudy view of exoplanets
Drake Deming
The lack of absorption features in the transmission spectrum of
exoplanet GJ 1214b rules out a hydrogen-rich atmosphere for the
planet. It is consistent with an atmosphere rich in water vapour
or abundant in clouds.
http://links.ealert.nature.com/ctt?kn=11&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Impacts of biodiversity on the emergence and transmission of
infectious diseases
Felicia Keesing, Lisa K. Belden, Peter Daszak, Andrew Dobson,
C. Drew Harvell et al.
Current unprecedented declines in biodiversity reduce the ability
of ecological...
http://links.ealert.nature.com/ctt?kn=73&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
NEWS & COMMENT
** Geoscience: How plants check global warming
http://links.ealert.nature.com/ctt?kn=46&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** The politics of climate (dis)belief
Francis Nicholson
http://links.ealert.nature.com/ctt?kn=60&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** How to conserve the tropics as they warm
Jedediah Brodie, Eric Post and William Laurance
http://links.ealert.nature.com/ctt?kn=59&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** More News & Comment on EARTH AND ENVIRONMENTAL SCIENCES
http://links.ealert.nature.com/ctt?kn=90&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
=========================== ADVERTISEMENT ===========================
The Natureevents Directory 2011
http://links.ealert.nature.com/ctt?kn=121&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
Inform a potential 1 million scientists about your scientific events.
Contact us now to be included in the 12th edition of the Natureevents
directory: c.paulsen@us.nature.com
T: +1 202 626 2522
=====================================================================
======================== CAREERS & JOBS ========================
** Publishing: A helping hand
Manuscript-editing services are growing. Can they turn a mediocre
paper into a publishable one? And at what cost?
http://links.ealert.nature.com/ctt?kn=119&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Postdoc unions
Canadian universities seek better working conditions.
http://links.ealert.nature.com/ctt?kn=87&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Awards for biomedicine
Grants aim to foster collaboration.
http://links.ealert.nature.com/ctt?kn=85&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Academic jobs safe
Scottish universities try to preserve research posts in the face of
cuts.
http://links.ealert.nature.com/ctt?kn=83&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Complex synthesis yields breast-cancer therapy
Drug approval marks culmination of a marathon trek from sea sponges
to clinic.
http://links.ealert.nature.com/ctt?kn=112&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Partners wanted to run research lab in space
NASA seeks wider research-community involvement in the International
Space Station.
http://links.ealert.nature.com/ctt?kn=106&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
** Follow the money
What was the impact of the nanotechnology funding boom of the past
ten years? Philip Shapira and Jue Wang have scrutinized the
literature to find out.
http://links.ealert.nature.com/ctt?kn=77&m=36041314&r=MjA1NzcwMjE4MQS2&b=2&j=ODg2MDYwMDQS1&mt=1&rt=0
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