The EDGE: Nature contents: 25 November 2010

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A*STAR Research - Highlighting the best of research at the Agency
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Recent Highlights
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Photonics: Optimizing the design of a compact coupler | Medical genetics:
Many a little makes a mickle | Stem cells: Brighten up | Cell biology:
A new player in protein secretion Microfluidics: A small mix-up |
Cell biology: Taking wraps off mammalian Rap1

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---THIS WEEK'S HIGHLIGHTS:

--Physical Sciences
-A geometric measure of dark energy with pairs of galaxies
One of cosmology's trickiest problems - how to measure the curvature
of the Universe - has been solved using the basic rules of geometry.
And what emerges is a flat Universe.
[ http://links.ealert.nature.com/ctt?kn=74&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0 ]

--Biological Sciences
-Direct conversion of human fibroblasts to multilineage blood progenitors
The direct conversion of human dermal fibroblasts to multipotent blood
progenitors has been achieved in vitro with the aid of just one
transcription factor, Oct-4. Cells made in this way could be of use
in cell replacement therapies and the treatment of haematopoietic
disorders.
[ http://links.ealert.nature.com/ctt?kn=77&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0 ]

--Physical Sciences
-Growth of graphene from solid carbon sources
Efforts to produce large sheets of monolayer (or few-layer) graphene
could receive a welcome boost from simple new procedure. Just by
baking solid carbon deposited on a metal catalyst substrate at 800 C,
it is possible to produce graphene in a single step.
[ http://links.ealert.nature.com/ctt?kn=70&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0 ]

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We are looking for innovations that offer a potential new
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These Awards cover: diagnostics; enabling technologies;
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UK-based academic researchers and companies are invited to apply by 7
January 2011
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--Podcast & Video
-This week, the origins of the world's first computer, sweet news on
how cells export sugars and how to measure dark energy. Plus, the
best of the rest from this week's Nature.
[ http://links.ealert.nature.com/ctt?kn=109&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0 ]

======================== NEWS AND COMMENT ========================
Read daily news coverage http://links.ealert.nature.com/ctt?kn=92&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

EDITORIALS
** The party's over
Caffeinated alcoholic drinks, popular with students, are now being
targeted by US regulators. But if government is serious about
addressing alcohol abuse, it must confront more powerful foes.
http://links.ealert.nature.com/ctt?kn=71&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Treated fairly?
Moves to price new pharmaceuticals sensibly shouldn't damage the
industry's health.
http://links.ealert.nature.com/ctt?kn=81&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Citizen scientists
Scientists should speak out on the environmental effects of ventures
such as tar-sands mining.
http://links.ealert.nature.com/ctt?kn=82&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

WORLD VIEW
** Copenhagen shows we need caution in Cancun
Next week's climate meeting in Mexico should avoid talk of more
ambitious targets, says Yvo de Boer. First, we need people to
believe in green growth.
http://links.ealert.nature.com/ctt?kn=122&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

SEVEN DAYS
** Seven days: 25 November 2010
The week in science
http://links.ealert.nature.com/ctt?kn=117&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

NEWS
** Cholera tightens grip on Haiti
Those tackling the epidemic are struggling to keep pace with an
escalating crisis.
http://links.ealert.nature.com/ctt?kn=118&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Korean deaths spark inquiry
Cases highlight the challenge of policing multinational trade in
stem-cell treatments.
http://links.ealert.nature.com/ctt?kn=115&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Nobel document triggers debate
Critics say that explanation of the 2010 award in physics slights
other contributions to graphene research.
http://links.ealert.nature.com/ctt?kn=116&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Drug giants turn their backs on RNA interference
A once much-touted technique faces a difficult transition to the clinic.
http://links.ealert.nature.com/ctt?kn=112&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Climate talks focus on lesser goals
With nations in gridlock over emissions, UN negotiators are
concentrating on side deals to revive an ailing process.
http://links.ealert.nature.com/ctt?kn=114&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** The roots of resistance
Learning how melanoma fights back may yield new therapies.
http://links.ealert.nature.com/ctt?kn=110&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

FEATURES
** Microbiology: The new germ theory
What can microbiologists who study human bowels learn from those who
study the bowels of Earth?
http://links.ealert.nature.com/ctt?kn=111&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Ancient astronomy: Mechanical inspiration
The ancient Greeks' vision of a geometrical Universe seemed to come
out of nowhere. Could their ideas have come from the internal
gearing of an ancient mechanism?
http://links.ealert.nature.com/ctt?kn=108&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

COMMENT
** Tar sands need solid science
As Canada exploits its oil sands ever faster, David Schindler calls
for industry-independent environmental monitoring to back up better
water-quality regulation.
http://links.ealert.nature.com/ctt?kn=78&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Call in the women
A critical mass of female voices changes the tenor of political and
corporate decisions -- and should be used to galvanize climate policy,
says Susan Buckingham.
http://links.ealert.nature.com/ctt?kn=80&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

BOOKS AND ARTS
** Conservation: China's national treasure
The panda's plight shows how protection often vies with economic
necessity, finds Jane Qiu.
http://links.ealert.nature.com/ctt?kn=67&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** History: Catching up with the Sun
Douglas Gough enjoys a wide-ranging tour of the many influences of
our nearest star.
http://links.ealert.nature.com/ctt?kn=55&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=54&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Sculpture: Terrible wonder
Alfred Keller's fastidious models of insects highlight his skill as
an observer and a sculptor, finds Martin Kemp.
http://links.ealert.nature.com/ctt?kn=58&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Innovation: The ideas lab
Jascha Hoffman reads about some creative research environments that
led to unexpected discoveries.
http://links.ealert.nature.com/ctt?kn=57&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

CORRESPONDENCE
** IPCC yet to assess geoengineering
Ottmar Edenhofer
http://links.ealert.nature.com/ctt?kn=60&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** An intellectual black hole
Larry Gilman
http://links.ealert.nature.com/ctt?kn=59&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Space telescope is worth the effort
Matt Mountain, John Grunsfeld and Heidi Hammel
http://links.ealert.nature.com/ctt?kn=62&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

CORRECTION
** Correction
http://links.ealert.nature.com/ctt?kn=125&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

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======================== BIOLOGICAL SCIENCES ========================
RESEARCH
** Direct conversion of human fibroblasts to multilineage blood progenitors
Eva Szabo, Shravanti Rampalli, Ruth M. Risueno, Angelique Schnerch,
Ryan Mitchell et al.
As is the case for embryo-derived stem cells, application of reprogrammed
human...
http://links.ealert.nature.com/ctt?kn=77&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Sugar transporters for intercellular exchange and nutrition of pathogens
Li-Qing Chen, Bi-Huei Hou, Sylvie Lalonde, Hitomi Takanaga,
Mara L. Hartung et al.
Sugar efflux transporters are essential for the maintenance of
animal blood glu...
http://links.ealert.nature.com/ctt?kn=61&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Structure and control of the actin regulatory WAVE complex
Zhucheng Chen, Dominika Borek, Shae B. Padrick, Timothy S. Gomez,
Zoltan Metlagel et al.
Members of the Wiskott-Aldrich syndrome protein (WASP) family control...
http://links.ealert.nature.com/ctt?kn=102&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Bottom-up effects of plant diversity on multitrophic interactions
in a biodiversity experiment
Christoph Scherber, Nico Eisenhauer, Wolfgang W. Weisser,
Bernhard Schmid, Winfried Voigt et al.
Biodiversity is rapidly declining, and this may negatively affect
ecosystem pro...
http://links.ealert.nature.com/ctt?kn=104&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Pericytes regulate the blood-brain barrier
Annika Armulik, Guillem Genove, Maarja Mae, Maya H. Nisancioglu,
Elisabet Wallgard et al.
The blood-brain barrier (BBB) consists of specific physical
barriers, e...
http://links.ealert.nature.com/ctt?kn=79&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Pericytes are required for blood-brain barrier integrity during
embryogenesis
Richard Daneman, Lu Zhou, Amanuel A. Kebede and Ben A. Barres
Vascular endothelial cells in the central nervous system (CNS) form
a barrier t...
http://links.ealert.nature.com/ctt?kn=91&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Selective activation of p53-mediated tumour suppression in
high-grade tumours
Melissa R. Junttila, Anthony N. Karnezis, Daniel Garcia,
Francesc Madriles, Roderik M. Kortlever et al.
Non-small cell lung carcinoma (NSCLC) is the leading cause of
cancer-related de...
http://links.ealert.nature.com/ctt?kn=88&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Stage-specific sensitivity to p53 restoration during lung cancer
progression
David M. Feldser, Kamena K. Kostova, Monte M. Winslow, Sarah E. Taylor,
Chris Cashman et al.
Tumorigenesis is a multistep process that results from the sequential
accumulat...
http://links.ealert.nature.com/ctt?kn=86&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Tension directly stabilizes reconstituted kinetochore-microtubule
attachments
Bungo Akiyoshi, Krishna K. Sarangapani, Andrew F. Powers,
Christian R. Nelson, Steve L. Reichow et al.
Kinetochores are macromolecular machines that couple chromosomes
to dynamic mic...
http://links.ealert.nature.com/ctt?kn=84&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Nanoscale architecture of integrin-based cell adhesions
Pakorn Kanchanawong, Gleb Shtengel, Ana M. Pasapera, Ericka B. Ramko,
Michael W. Davidson et al.
Cell adhesions to the extracellular matrix (ECM) are necessary for
morphogenesi...
http://links.ealert.nature.com/ctt?kn=100&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** The amino-terminal disease hotspot of ryanodine receptors forms a
cytoplasmic vestibule
Ching-Chieh Tung, Paolo A. Lobo, Lynn Kimlicka and Filip Van Petegem
Many physiological events require transient increases in cytosolic
Ca2+ concent...
http://links.ealert.nature.com/ctt?kn=97&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Single-molecule imaging reveals mechanisms of protein disruption
by a DNA translocase
Ilya J. Finkelstein, Mari-Liis Visnapuu and Eric C. Greene
In physiological settings, nucleic-acid translocases must act on
substrates occ...
http://links.ealert.nature.com/ctt?kn=95&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Calcium-dependent phospholipid scrambling by TMEM16F
Jun Suzuki, Masato Umeda, Peter J. Sims and Shigekazu Nagata
In all animal cells, phospholipids are asymmetrically distributed
between the o...
http://links.ealert.nature.com/ctt?kn=93&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Structures of APC/CCdh1 with substrates identify Cdh1 and Apc10 as
the D-box co-receptor
Paula C. A. da Fonseca, Eric H. Kong, Ziguo Zhang, Anne Schreiber,
Mark. A. Williams et al.
The ubiquitylation of cell-cycle regulatory proteins by the large
multimeric an...
http://links.ealert.nature.com/ctt?kn=35&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or
N-RAS upregulation
Ramin Nazarian, Hubing Shi, Qi Wang, Xiangju Kong, Richard C. Koya et al.
Activating B-RAF(V600E) (also known as BRAF) kinase mutations occur
in [sim]7...
http://links.ealert.nature.com/ctt?kn=31&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** COT drives resistance to RAF inhibition through MAP kinase pathway
reactivation
Cory M. Johannessen, Jesse S. Boehm, So Young Kim, Sapana R. Thomas,
Leslie Wardwell et al.
Oncogenic mutations in the serine/threonine kinase B-RAF
(also known as BRAF) a...
http://links.ealert.nature.com/ctt?kn=32&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Tumour vascularization via endothelial differentiation of glioblastoma
stem-like cells
Lucia Ricci-Vitiani, Roberto Pallini, Mauro Biffoni, Matilde Todaro,
Gloria Invernici et al.
Glioblastoma is a highly angiogenetic malignancy, the neoformed vessels
of whic...
http://links.ealert.nature.com/ctt?kn=26&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Glioblastoma stem-like cells give rise to tumour endothelium
Rong Wang, Kalyani Chadalavada, Jennifer Wilshire, Urszula Kowalik,
Koos E. Hovinga et al.
Glioblastoma (GBM) is among the most aggressive of human cancers.
A key feature...
http://links.ealert.nature.com/ctt?kn=28&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Bold claims for optogenetics
Nikos K. Logothetis
Arising from J. H. Lee et al. Nature 465, 788-792 (2010); Lee et al.
In a recent Letter to Nature, Lee and colleagues combined optogenetic
stimulati...
http://links.ealert.nature.com/ctt?kn=29&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Cell biology: Raiding the sweet shop
Nicholas J. Talbot
A type of sugar transporter has been discovered that exports glucose
from cells. In plants, these transporters are targeted by
disease-causing microbes that divert sugar production for their own use.
http://links.ealert.nature.com/ctt?kn=30&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Palaeoanthropology: Early Homo sapiens in China
Robin Dennell
The timing of the dispersal of our species from Africa is a continuing
and lively topic of debate. Evidence that modern humans existed in
China more than 100,000 years ago is both equivocal and thought-provoking.
http://links.ealert.nature.com/ctt?kn=22&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Cell biology: Import and nuclear size
Orna Cohen-Fix
The size of a cell's nucleus is usually proportional to the size of
the cell itself. How are the two linked? The answer lies, at least in
part, in the import of one or more cytoplasmic cargoes into the nucleus.
http://links.ealert.nature.com/ctt?kn=23&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Mechanoregulation: Cellular seat belts
Yuta Shimamoto and Tarun M. Kapoor
Accurate cell division depends on proper attachment of chromosomes
to the microtubule-based division apparatus. An impressive in vitro
study shows how applied force plays a pivotal part in regulating
such attachment.
http://links.ealert.nature.com/ctt?kn=24&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Cancer: The blind spot of p53
Anton Berns
It is hoped that reactivating the tumour-suppressor protein p53 will
help to combat cancer. However, fresh evidence suggests it is unlikely
that all cells in a tumour will respond to such treatment.
http://links.ealert.nature.com/ctt?kn=25&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

NEWS & COMMENT
** Genomics: Similar bodies, different genomes
http://links.ealert.nature.com/ctt?kn=47&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Cancer: Metabolic link to breast cancer
http://links.ealert.nature.com/ctt?kn=45&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Evolution: Neanderthals matured fast
http://links.ealert.nature.com/ctt?kn=46&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Structural biology: Dopamine receptor revealed
http://links.ealert.nature.com/ctt?kn=43&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Developmental biology: Blood-vessel cells turn to bone
http://links.ealert.nature.com/ctt?kn=44&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Gene therapy: Small RNAs aid cell transplants
http://links.ealert.nature.com/ctt?kn=41&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Zoology: Fish cocoons block biting bugs
http://links.ealert.nature.com/ctt?kn=42&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** The party's over
Caffeinated alcoholic drinks, popular with students, are now being
targeted by US regulators. But if government is serious about
addressing alcohol abuse, it must confront more powerful foes.
http://links.ealert.nature.com/ctt?kn=71&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Conservation: China's national treasure
The panda's plight shows how protection often vies with economic
necessity, finds Jane Qiu.
http://links.ealert.nature.com/ctt?kn=67&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=54&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Sculpture: Terrible wonder
Alfred Keller's fastidious models of insects highlight his skill
as an observer and a sculptor, finds Martin Kemp.
http://links.ealert.nature.com/ctt?kn=58&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Turning point: Mary Gehring
How to thrive as a plant biologist in a biomedical research environment.
http://links.ealert.nature.com/ctt?kn=123&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** More News & Comment on BIOLOGICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=92&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

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=====================================================================

======================== CHEMICAL SCIENCES ========================
RESEARCH
** Sugar transporters for intercellular exchange and nutrition of
pathogens
Li-Qing Chen, Bi-Huei Hou, Sylvie Lalonde, Hitomi Takanaga,
Mara L. Hartung et al.
Sugar efflux transporters are essential for the maintenance of
animal blood glu...
http://links.ealert.nature.com/ctt?kn=61&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Growth of graphene from solid carbon sources
Zhengzong Sun, Zheng Yan, Jun Yao, Elvira Beitler, Yu Zhu et al.
Monolayer graphene was first obtained as a transferable material in
2004 and ha...
http://links.ealert.nature.com/ctt?kn=70&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Nanotechnology: Peptides as biological semiconductors
Charlotte A. E. Hauser and Shuguang Zhang
A simple peptide that assembles into desirable nanoscale structures is
a striking example of how the whole can be greater than the sum of its
parts. What's more, the assembly process is controllably reversible.
http://links.ealert.nature.com/ctt?kn=40&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Mechanoregulation: Cellular seat belts
Yuta Shimamoto and Tarun M. Kapoor
Accurate cell division depends on proper attachment of chromosomes to
the microtubule-based division apparatus. An impressive in vitro study
shows how applied force plays a pivotal part in regulating such attachment.
http://links.ealert.nature.com/ctt?kn=24&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

NEWS & COMMENT
** Chemistry: Molecular matchmaking
http://links.ealert.nature.com/ctt?kn=36&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** More News & Comment on CHEMICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=92&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

======================== PHYSICAL SCIENCES ========================
RESEARCH
** A geometric measure of dark energy with pairs of galaxies
Christian Marinoni and Adeline Buzzi
Observations indicate that the expansion of the Universe is
accelerating, which...
http://links.ealert.nature.com/ctt?kn=74&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** The dynamical mass of a classical Cepheid variable star in an
eclipsing binary system
G. Pietrzynski, I. B. Thompson, W. Gieren, D. Graczyk, G. Bono et al.
Stellar pulsation theory provides a means of determining the masses
of pulsatin...
http://links.ealert.nature.com/ctt?kn=10&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Bose-Einstein condensation of photons in an optical microcavity
Jan Klaers, Julian Schmitt, Frank Vewinger and Martin Weitz
Bose-Einstein condensation (BEC)--the macroscopic ground-state a...
http://links.ealert.nature.com/ctt?kn=11&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Snapshots of cooperative atomic motions in the optical suppression
of charge density waves
Maximilian Eichberger, Hanjo Schafer, Marina Krumova, Markus Beyer,
Jure Demsar et al.
Macroscopic quantum phenomena such as high-temperature superconductivity,
colos...
http://links.ealert.nature.com/ctt?kn=12&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Cosmology: Geometry of the Universe
Alan Heavens
A neat way of measuring the geometry of the Universe offers a new test
of the standard cosmological model. It probes, among other things,
the elusive dark energy thought to be driving the Universe's expansion.
http://links.ealert.nature.com/ctt?kn=13&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Quantum optics: Particles of light
James Anglin
Bose-Einstein condensation, which demonstrates the wave nature of
material particles, now offers further illumination of wave-particle
duality: it has been observed in light itself.
http://links.ealert.nature.com/ctt?kn=1&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

NEWS & COMMENT
** Material science: Stopping ice before it forms
http://links.ealert.nature.com/ctt?kn=2&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=54&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** IPCC yet to assess geoengineering
Ottmar Edenhofer
http://links.ealert.nature.com/ctt?kn=60&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** An intellectual black hole
Larry Gilman
http://links.ealert.nature.com/ctt?kn=59&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Space telescope is worth the effort
Matt Mountain, John Grunsfeld and Heidi Hammel
http://links.ealert.nature.com/ctt?kn=62&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Small science yields big growth
Nanomaterials have evolved from innovation to application -- and
the career possibilities have blossomed.
http://links.ealert.nature.com/ctt?kn=89&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** More News & Comment on PHYSICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=92&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

======================== EARTH AND ENVIRONMENTAL SCIENCES ========================
RESEARCH
NEWS & COMMENT
** Geology: Hills emerge as glaciers retreat
http://links.ealert.nature.com/ctt?kn=5&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Tar sands need solid science
As Canada exploits its oil sands ever faster, David Schindler calls
for industry-independent environmental monitoring to back up better
water-quality regulation.
http://links.ealert.nature.com/ctt?kn=78&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=54&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** IPCC yet to assess geoengineering
Ottmar Edenhofer
http://links.ealert.nature.com/ctt?kn=60&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** An intellectual black hole
Larry Gilman
http://links.ealert.nature.com/ctt?kn=59&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Space telescope is worth the effort
Matt Mountain, John Grunsfeld and Heidi Hammel
http://links.ealert.nature.com/ctt?kn=62&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** More News & Comment on EARTH AND ENVIRONMENTAL SCIENCES
http://links.ealert.nature.com/ctt?kn=92&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

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=====================================================================

======================== CAREERS & JOBS ========================
** Small science yields big growth
Nanomaterials have evolved from innovation to application -- and
the career possibilities have blossomed.
http://links.ealert.nature.com/ctt?kn=87&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Turning point: Mary Gehring
How to thrive as a plant biologist in a biomedical research environment.
http://links.ealert.nature.com/ctt?kn=85&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Overseas enrolment up
A 30% rise in students from China is behind record highs at US
institutions.
http://links.ealert.nature.com/ctt?kn=83&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Changing order
Emerging nations challenging for top research spots.
http://links.ealert.nature.com/ctt?kn=98&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Faculty seek support
Junior staff want more grant-applications help from institutions.
http://links.ealert.nature.com/ctt?kn=96&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Copenhagen shows we need caution in Cancun
Next week's climate meeting in Mexico should avoid talk of more
ambitious targets, says Yvo de Boer. First, we need people to
believe in green growth.
http://links.ealert.nature.com/ctt?kn=122&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Korean deaths spark inquiry
Cases highlight the challenge of policing multinational trade
in stem-cell treatments.
http://links.ealert.nature.com/ctt?kn=115&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** Drug giants turn their backs on RNA interference
A once much-touted technique faces a difficult transition to
the clinic.
http://links.ealert.nature.com/ctt?kn=112&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

** IPCC yet to assess geoengineering
Ottmar Edenhofer
http://links.ealert.nature.com/ctt?kn=60&m=36023731&r=MjA1NzcwMjE4MQS2&b=2&j=ODc5ODM0NjAS1&mt=1&rt=0

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The EDGE

Wednesday, November 24, 2010

Nature contents: 25 November 2010

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