The EDGE: Nature contents: 21 April 2011

Nature Alert
The science that matters. Every week.

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View Table of Contents http://links.ealert.nature.com/ctt?kn=46&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

=========================== ADVERTISEMENT ===========================
Nature Publishing Index 2010: Asia-Pacific http://links.ealert.nature.com/ctt?kn=113&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

Announcing the publication of the 2010 rankings of top institutions
and countries in the Asia-Pacific by number of papers published
during 2010.
NEW this year is a global ranking of the top 50 institutions in the
world, placing the Asia-Pacific in a global context.
You can download the yearly print publication or view the
Nature Publishing Index: Asia-Pacific, which is updated weekly.
NB: the supplement was written before the earthquake disaster in Japan

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=========================== ADVERTISEMENT ===========================
---THIS WEEK'S HIGHLIGHTS:

--Earth & Environmental Sciences
-The auroral footprint of Enceladus on Saturn
A Cassini fly-by within 55 km of the icy moon Enceladus reveals emissions
powerful enough to cause an auroral footprint on the ringed planet.
[ http://links.ealert.nature.com/ctt?kn=90&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0 ]

--Physical Sciences
-Optically healable supramolecular polymers
Smart materials that can repair themselves with a little help from
exposure to ultraviolet light could have many practical applications.
[ http://links.ealert.nature.com/ctt?kn=92&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0 ]

--Biological Sciences
-A transient placental source of serotonin for the fetal forebrain
During early pregnancy the placenta is a significant source of fetal
serotonin, providing the neurotransmitter to the fetus until an
endogenous source in the fetus itself is able to take over.
[ http://links.ealert.nature.com/ctt?kn=87&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0 ]

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http://links.ealert.nature.com/ctt?kn=112&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0
042011
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--Podcast & Video
-This week, a self-healing material, a mysterious source of and does
the PhD need a revamp? Plus, the rest of the best from Nature.
[ http://links.ealert.nature.com/ctt?kn=117&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0 ]
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======================== NEWS AND COMMENT ========================
Read daily news coverage http://links.ealert.nature.com/ctt?kn=119&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

EDITORIALS
** Accidents in waiting
Every researcher and institution should question their own attitudes
to safety in the lab after the death of an undergraduate student in a
Yale University workshop.
http://links.ealert.nature.com/ctt?kn=88&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Fix the PhD
No longer a guaranteed ticket to an academic career, the PhD system
needs a serious rethink.
http://links.ealert.nature.com/ctt?kn=96&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Home truths
A new report offers useful insight into the continuing stalemate
over global warming.
http://links.ealert.nature.com/ctt?kn=97&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

WORLD VIEW
** Reform the PhD system or close it down
There are too many doctoral programmes, producing too many PhDs for
the job market. Shut some and change the rest, says Mark C. Taylor.
http://links.ealert.nature.com/ctt?kn=44&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

SEVEN DAYS
** Seven days: 21 April 2011
The week in science
http://links.ealert.nature.com/ctt?kn=19&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

NEWS
** US budget a taste of battles to come
Deal leaves science agencies with less but avoids deep cuts.
http://links.ealert.nature.com/ctt?kn=45&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Canadian research shift makes waves
Agency's focus on industry-driven projects raises concerns that basic
science will suffer.
http://links.ealert.nature.com/ctt?kn=18&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** A death in the lab
Fatality adds further momentum to calls for a shake-up in academic
safety culture.
http://links.ealert.nature.com/ctt?kn=17&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Cancer theory faces doubts
A leading explanation for how disease migrates falls short on
clinical evidence.
http://links.ealert.nature.com/ctt?kn=25&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Nuclear safety chief calls for reform
Laurent Stricker says Japan's nuclear disaster should mark a turning
point for the industry.
http://links.ealert.nature.com/ctt?kn=24&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

FEATURES
** Education: The PhD factory
The world is producing more PhDs than ever before. Is it time to stop?
http://links.ealert.nature.com/ctt?kn=22&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Education: Rethinking PhDs
Fix it, overhaul it or skip it completely — institutions and individuals
are taking innovative approaches to postgraduate science training.
http://links.ealert.nature.com/ctt?kn=20&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

COMMENT
** Seven ages of the PhD
Scientists share memories of doing doctorates in different decades,
disciplines and locations, from the hunt for the structure of DNA
to deciphering the human genome.
http://links.ealert.nature.com/ctt?kn=93&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** The art of conservation
As the World Wide Fund for Nature (WWF) turns 50, Henry Nicholls
traces how the evolution of conservation practice has been echoed in
the various incarnations of WWF's iconic pandas, and other conservation
logos.
http://links.ealert.nature.com/ctt?kn=95&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

BOOKS AND ARTS
** Conservation: Bringing back wildlife
A scholarly history of the WWF highlights the gap between advocacy
and action, finds Nancy Lee Nash.
http://links.ealert.nature.com/ctt?kn=85&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=73&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Climate change: A dose of reality
Tony McMichael welcomes an overview of an under-recognized climate
issue: the threat to human health.
http://links.ealert.nature.com/ctt?kn=72&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Art: Grime and punishment
Daniel Cressey finds there is more to dirt than disease at a London
exhibition.
http://links.ealert.nature.com/ctt?kn=76&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Q&A: Animal distractions
Isabella Rossellini, star of films including Blue Velvet (1986) and
Big Night (1996), has made a series of short films on the mating
rituals of insects and sea creatures. As her latest humorous biopic
debuts in the United States, Rossellini explains why she is fascinated
by animals.
http://links.ealert.nature.com/ctt?kn=75&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

CORRESPONDENCE
** Doing the maths on the green economy
Peter Victor and Tim Jackson
http://links.ealert.nature.com/ctt?kn=78&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Academia resists clean-up in Romania
Liviu Giosan
http://links.ealert.nature.com/ctt?kn=77&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Science failed to self-regulate
Frederik Trettin and Tobias Bunde
http://links.ealert.nature.com/ctt?kn=80&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Fund biodiversity collections
Flavio A. Bockmann
http://links.ealert.nature.com/ctt?kn=79&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

OBITUARY
** Jurg Tschopp (1951-2011)
Immunologist whose discoveries transformed patients' lives.
http://links.ealert.nature.com/ctt?kn=110&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

CORRECTIONS
** Corrections
http://links.ealert.nature.com/ctt?kn=26&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Correction
http://links.ealert.nature.com/ctt?kn=111&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

=========================== ADVERTISEMENT ===========================
The New York Stem Cell Foundation
requests applications from early career investigators in the US,
Canada and the UK to cultivate research that will explore the
therapeutic potential of human stem cells. The award provides
$1.5M USD over 5 years. Closing date July 8, 2011.

http://links.ealert.nature.com/ctt?kn=67&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0
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======================== BIOLOGICAL SCIENCES ========================
RESEARCH
** Catecholamine receptor polymorphisms affect decision-making in
C. elegans
Andres Bendesky, Makoto Tsunozaki, Matthew V. Rockman, Leonid Kruglyak
and Cornelia I. Bargmann
Innate behaviours are flexible: they change rapidly in response to
transient en...
http://links.ealert.nature.com/ctt?kn=94&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Caspase signalling controls microglia activation and neurotoxicity
Miguel A. Burguillos, Tomas Deierborg, Edel Kavanagh, Annette Persson,
Nabil Hajji et al.
Activation of microglia and inflammation-mediated neurotoxicity are
suggested t...
http://links.ealert.nature.com/ctt?kn=103&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Crystal structure of inhibitor of [kappa]B kinase [beta]
Guozhou Xu, Yu-Chih Lo, Qiubai Li, Gennaro Napolitano, Xuefeng Wu et al.
Inhibitor of [kappa]B (I[kappa]B) kinase (IKK) phosphorylates
I[kappa]B protein...
http://links.ealert.nature.com/ctt?kn=100&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Metabolic trade-offs and the maintenance of the fittest and the
flattest
Robert E. Beardmore, Ivana Gudelj, David A. Lipson and Laurence D. Hurst
How is diversity maintained? Environmental heterogeneity is considered
to be im...
http://links.ealert.nature.com/ctt?kn=99&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** A transient placental source of serotonin for the fetal forebrain
Alexandre Bonnin, Nick Goeden, Kevin Chen, Melissa L. Wilson,
Jennifer King et al.
Serotonin (5-hydroxytryptamine or 5-HT) is thought to regulate
neurodevelopment...
http://links.ealert.nature.com/ctt?kn=87&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Neuronal activity is required for the development of specific
cortical interneuron subtypes
Natalia V. De Marco Garcia, Theofanis Karayannis and Gord Fishell
Electrical activity has been shown to regulate development in a variety
of spec...
http://links.ealert.nature.com/ctt?kn=98&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Ephrin Bs are essential components of the Reelin pathway to
regulate neuronal migration
Aycan Senturk, Sylvia Pfennig, Alexander Weiss, Katja Burk and
Amparo Acker-Palmer
Coordinated migration of neurons in the developing and adult brain
is essential...
http://links.ealert.nature.com/ctt?kn=108&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** TRIM5 is an innate immune sensor for the retrovirus capsid lattice
Thomas Pertel, Stephane Hausmann, Damien Morger, Sara Zuger,
Jessica Guerra et al.
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection
by human im...
http://links.ealert.nature.com/ctt?kn=106&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** A Raf-induced allosteric transition of KSR stimulates
phosphorylation of MEK
Damian F. Brennan, Arvin C. Dar, Nicholas T. Hertz, William C. H. Chao,
Alma L. Burlingame et al.
In metazoans, the Ras-Raf-MEK (mitogen-activated protein-kinase...
http://links.ealert.nature.com/ctt?kn=105&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Eutherian mammals use diverse strategies to initiate X-chromosome
inactivation during development
Ikuhiro Okamoto, Catherine Patrat, Dominique Thepot, Nathalie Peynot,
Patricia Fauque et al.
X-chromosome inactivation (XCI) in female mammals allows dosage
compensation fo...
http://links.ealert.nature.com/ctt?kn=104&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Genome-wide analysis reveals novel molecular features of mouse
recombination hotspots
Fatima Smagulova, Ivan V. Gregoretti, Kevin Brick, Pavel Khil,
R. Daniel Camerini-Otero et al.
Meiotic recombination predominantly occurs at discrete genomic loci
called reco...
http://links.ealert.nature.com/ctt?kn=51&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Enterotypes of the human gut microbiome
Manimozhiyan Arumugam, Jeroen Raes, Eric Pelletier, Denis Le Paslier,
Takuji Yamada et al.
Our knowledge of species and functional composition of the human gut
microbiome...
http://links.ealert.nature.com/ctt?kn=40&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** A synthetic homing endonuclease-based gene drive system in the
human malaria mosquito
Nikolai Windbichler, Miriam Menichelli, Philippos Aris Papathanos,
Summer B. Thyme, Hui Li et al.
Genetic methods of manipulating or eradicating disease vector
populations have ...
http://links.ealert.nature.com/ctt?kn=41&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Neuropsin cleaves EphB2 in the amygdala to control anxiety
Benjamin K. Attwood, Julie-Myrtille Bourgognon, Satyam Patel,
Mariusz Mucha, Emanuele Schiavon et al.
A minority of individuals experiencing traumatic events develop
anxiety disorde...
http://links.ealert.nature.com/ctt?kn=34&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Crystal structure of oxygen-evolving photosystem II at a resolution
of 1.9 A
Yasufumi Umena, Keisuke Kawakami, Jian-Ren Shen and Nobuo Kamiya
Photosystem II is the site of photosynthetic water oxidation and
contains 20 su...
http://links.ealert.nature.com/ctt?kn=36&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Differential microRNA regulation of HLA-C expression and its
association with HIV control
Smita Kulkarni, Ram Savan, Ying Qi, Xiaojiang Gao, Yuko Yuki et al.
The HLA-C locus is distinct relative to the other classical HLA class
I loci in...
http://links.ealert.nature.com/ctt?kn=37&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Acetylation-dependent regulation of endothelial Notch signalling by
the SIRT1 deacetylase
Virginia Guarani, Gianluca Deflorian, Claudio A. Franco, Marcus Kruger,
Li-Kun Phng et al.
Notch signalling is a key intercellular communication mechanism that
is essenti...
http://links.ealert.nature.com/ctt?kn=39&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Stem-cell-triggered immunity through CLV3p-FLS2 signalling
Horim Lee, Ok-Kyong Chah and Jen Sheen
Stem cells in the shoot apical meristem (SAM) of plants are the
self-renewable ...
http://links.ealert.nature.com/ctt?kn=30&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Suppression of TH17 differentiation and autoimmunity by a synthetic
ROR ligand
Laura A. Solt, Naresh Kumar, Philippe Nuhant, Yongjun Wang,
Janelle L. Lauer et al.
T-helper cells that produce interleukin-17 (TH17 cells) are a recently
identifi...
http://links.ealert.nature.com/ctt?kn=31&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Developmental biology: Remarkable role for the placenta
Ron McKay
The placenta does not only act as the essential link between the
developing embryo and its mother. Unexpectedly, it is also a source
of serotonin -- a neurotransmitter that is crucial for embryonic brain
development.
http://links.ealert.nature.com/ctt?kn=32&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Evolutionary biology: Light sense
Daniel Osorio
Evidence that a larval brachiopod has ciliary photoreceptors that are
directionally selective, and therefore may function as eyes, bears
on an enduring puzzle about photoreceptor evolution in animals.
http://links.ealert.nature.com/ctt?kn=33&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Cancer: Macrophages limit chemotherapy
Michele De Palma and Claire E. Lewis
A major hurdle to successful cancer treatment is tumour resistance to
chemotherapy. White blood cells called macrophages often infiltrate
tumours in large numbers, and now appear to promote tumour chemoresistance.
http://links.ealert.nature.com/ctt?kn=63&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Immunology: TRIM5 does double duty
Christopher Aiken and Sebastian Joyce
TRIM5 proteins limit retroviral infection by targeting the viral coat.
It now seems that these proteins can also serve as pattern-recognition
receptors, which initiate cellular innate immune responses.
http://links.ealert.nature.com/ctt?kn=61&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

NEWS & COMMENT
** Ecology: Jonah and the waterfowl
http://links.ealert.nature.com/ctt?kn=62&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Virology: Stubborn virus grows in sinus
http://links.ealert.nature.com/ctt?kn=59&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Stem cells: New ways to change fates
http://links.ealert.nature.com/ctt?kn=60&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Behaviour: Diversity beats ability
http://links.ealert.nature.com/ctt?kn=57&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Cancer Biology: Laying siege to cancer
http://links.ealert.nature.com/ctt?kn=58&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Climate Change: Sea ice penguin theory sinks
http://links.ealert.nature.com/ctt?kn=55&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Neuroscience: Sleep deprivation: a risky business
http://links.ealert.nature.com/ctt?kn=56&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Conservation: Bringing back wildlife
A scholarly history of the WWF highlights the gap between advocacy
and action, finds Nancy Lee Nash.
http://links.ealert.nature.com/ctt?kn=85&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=73&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Q&A: Animal distractions
Isabella Rossellini, star of films including Blue Velvet (1986) and
Big Night (1996), has made a series of short films on the mating rituals
of insects and sea creatures. As her latest humorous biopic debuts in
the United States, Rossellini explains why she is fascinated by animals.
http://links.ealert.nature.com/ctt?kn=75&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Jurg Tschopp (1951-2011)
Immunologist whose discoveries transformed patients' lives.
http://links.ealert.nature.com/ctt?kn=110&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** What is a PhD really worth?
To secure elusive funding, entrepreneurs must understand the financial
landscape and the motivations of investing firms.
http://links.ealert.nature.com/ctt?kn=52&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** More News & Comment on BIOLOGICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=68&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

=========================== ADVERTISEMENT ===========================
76th Cold Spring Harbor Symposium on Quantitative Biology

METABOLISM & DISEASE

June 1 - 6, 2011

Cold Spring Harbor Laboratory, New York

Aging / Bone / Cancer / Cellular Metabolism / Circadian Rhythms/
Diabetes / Diet / Energy Regulation / Hormones /
Metabolic Signaling / Mitochondria / Nuclear Receptors /
Obesity / Organ Systems / Hypoxia / Stress & Protein Homeostasis

http://links.ealert.nature.com/ctt?kn=118&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0
=====================================================================

======================== CHEMICAL SCIENCES ========================
RESEARCH
** Crystal structure of inhibitor of [kappa]B kinase [beta]
Guozhou Xu, Yu-Chih Lo, Qiubai Li, Gennaro Napolitano,
Xuefeng Wu et al.
Inhibitor of [kappa]B (I[kappa]B) kinase (IKK) phosphorylates
I[kappa]B protein...
http://links.ealert.nature.com/ctt?kn=100&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Optically healable supramolecular polymers
Mark Burnworth, Liming Tang, Justin R. Kumpfer, Andrew J. Duncan,
Frederick L. Beyer et al.
Polymers with the ability to repair themselves after sustaining damage
could ex...
http://links.ealert.nature.com/ctt?kn=92&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** A Raf-induced allosteric transition of KSR stimulates phosphorylation
of MEK
Damian F. Brennan, Arvin C. Dar, Nicholas T. Hertz, William C. H. Chao,
Alma L. Burlingame et al.
In metazoans, the Ras-Raf-MEK (mitogen-activated protein-kinase...
http://links.ealert.nature.com/ctt?kn=105&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** The Soret effect and isotopic fractionation in high-temperature
silicate melts
Gerardo Dominguez, Gautam Wilkins and Mark H. Thiemens
Diffusion in condensed phases is a ubiquitous but poorly understood
phenomenon....
http://links.ealert.nature.com/ctt?kn=10&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Materials chemistry: Spot-on healing
Nancy R. Sottos and Jeffrey S. Moore
Rubbery polymers have been made in which damage is healed by exposure
to light. The healing mechanism allows localized, on-demand repair,
and might help to extend the lifetimes of materials for many applications.
http://links.ealert.nature.com/ctt?kn=11&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

NEWS & COMMENT
** Accidents in waiting
Every researcher and institution should question their own attitudes
to safety in the lab after the death of an undergraduate student in
a Yale University workshop.
http://links.ealert.nature.com/ctt?kn=88&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** More News & Comment on CHEMICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=38&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

======================== PHYSICAL SCIENCES ========================
RESEARCH
** Quantum simulation of antiferromagnetic spin chains in an optical
lattice
Jonathan Simon, Waseem S. Bakr, Ruichao Ma, M. Eric Tai,
Philipp M. Preiss et al.
Understanding exotic forms of magnetism in quantum mechanical systems
is a cent...
http://links.ealert.nature.com/ctt?kn=12&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** The auroral footprint of Enceladus on Saturn
Wayne R. Pryor, Abigail M. Rymer, Donald G. Mitchell, Thomas W. Hill,
David T. Young et al.
Although there are substantial differences between the magnetospheres
of Jupite...
http://links.ealert.nature.com/ctt?kn=90&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Optically healable supramolecular polymers
Mark Burnworth, Liming Tang, Justin R. Kumpfer, Andrew J. Duncan,
Frederick L. Beyer et al.
Polymers with the ability to repair themselves after sustaining
damage could ex...
http://links.ealert.nature.com/ctt?kn=92&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Sharply increased mass loss from glaciers and ice caps in the
Canadian Arctic Archipelago
Alex S. Gardner, Geir Moholdt, Bert Wouters, Gabriel J. Wolken,
David O. Burgess et al.
Mountain glaciers and ice caps are contributing significantly to
present rates ...
http://links.ealert.nature.com/ctt?kn=13&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Materials chemistry: Spot-on healing
Nancy R. Sottos and Jeffrey S. Moore
Rubbery polymers have been made in which damage is healed by exposure
to light. The healing mechanism allows localized, on-demand repair,
and might help to extend the lifetimes of materials for many
applications.
http://links.ealert.nature.com/ctt?kn=11&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Atomic physics: A route to quantum magnetism
Ian B. Spielman
The trend towards using ultracold atoms as simulators of condensed-matter
and many-body phenomena is gaining momentum. These systems can now be
used to simulate quantum magnetism.
http://links.ealert.nature.com/ctt?kn=1&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Electronics: Power surfing on waves
Min Hyung Lee and Ali Javey
Wavy strips of piezoelectric materials on stretchable substrates can
both withstand larger applied mechanical strain without cracking and
harvest energy more efficiently than their flat counterparts.
http://links.ealert.nature.com/ctt?kn=2&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

NEWS & COMMENT
** Astronomy: Sharper cosmic pencils
http://links.ealert.nature.com/ctt?kn=4&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Optical Physics: A liquid of photons
http://links.ealert.nature.com/ctt?kn=5&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Mechanics: A stable, riderless bicycle
http://links.ealert.nature.com/ctt?kn=6&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Climate Change: Sea ice penguin theory sinks
http://links.ealert.nature.com/ctt?kn=55&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Home truths
A new report offers useful insight into the continuing stalemate over global warming.
http://links.ealert.nature.com/ctt?kn=97&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** More News & Comment on PHYSICAL SCIENCES
http://links.ealert.nature.com/ctt?kn=50&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

======================== EARTH AND ENVIRONMENTAL SCIENCES ========================
RESEARCH
** The auroral footprint of Enceladus on Saturn
Wayne R. Pryor, Abigail M. Rymer, Donald G. Mitchell, Thomas W. Hill,
David T. Young et al.
Although there are substantial differences between the magnetospheres
of Jupite...
http://links.ealert.nature.com/ctt?kn=90&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Thermal history of Mars inferred from orbital geochemistry of
volcanic provinces
David Baratoux, Michael J. Toplis, Marc Monnereau and Olivier Gasnault
Reconstruction of the geological history of Mars has been the focus of
consider...
http://links.ealert.nature.com/ctt?kn=7&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

NEWS & COMMENT
** Climate Change: Sea ice penguin theory sinks
http://links.ealert.nature.com/ctt?kn=55&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Books in brief
http://links.ealert.nature.com/ctt?kn=73&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Doing the maths on the green economy
Peter Victor and Tim Jackson
http://links.ealert.nature.com/ctt?kn=78&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Fund biodiversity collections
Flavio A. Bockmann
http://links.ealert.nature.com/ctt?kn=79&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** More News & Comment on EARTH AND ENVIRONMENTAL SCIENCES
http://links.ealert.nature.com/ctt?kn=49&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

=========================== ADVERTISEMENT ===========================
Nature Special: The Future of the PhD

Scientists attaining a PhD gain entry to an academic elite - but it's
not as elite as it once was. This week in Nature a series of articles
discuss what the problems with science PhD's are - and whether they
need reinvention?

Access this Special online and join in the debate.
http://links.ealert.nature.com/ctt?kn=47&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

=====================================================================

======================== CAREERS & JOBS ========================
** Start-ups: In search of venture capital
To secure elusive funding, entrepreneurs must understand the financial
landscape and the motivations of investing firms.
http://links.ealert.nature.com/ctt?kn=124&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** What is a PhD really worth?
To secure elusive funding, entrepreneurs must understand the financial
landscape and the motivations of investing firms.
http://links.ealert.nature.com/ctt?kn=101&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Accidents in waiting
Every researcher and institution should question their own attitudes
to safety in the lab after the death of an undergraduate student in
a Yale University workshop.
http://links.ealert.nature.com/ctt?kn=88&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Education: The PhD factory
The world is producing more PhDs than ever before. Is it time to stop?
http://links.ealert.nature.com/ctt?kn=22&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Seven ages of the PhD
Scientists share memories of doing doctorates in different decades,
disciplines and locations, from the hunt for the structure of DNA
to deciphering the human genome.
http://links.ealert.nature.com/ctt?kn=93&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Academia resists clean-up in Romania
Liviu Giosan
http://links.ealert.nature.com/ctt?kn=77&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Science failed to self-regulate
Frederik Trettin and Tobias Bunde
http://links.ealert.nature.com/ctt?kn=80&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

** Fund biodiversity collections
Flavio A. Bockmann
http://links.ealert.nature.com/ctt?kn=79&m=36530026&r=MjA1NzcwMjE4MQS2&b=2&j=OTk1ODY3MjgS1&mt=1&rt=0

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The EDGE

Wednesday, April 20, 2011

Nature contents: 21 April 2011

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